PALEONEUROBIOLOGY

Paleopathology has, with few exceptions, not identified diseases of the nervous system. We use the term Paleoneurobiology to encompass a branch of knowledge concerned with the study of the neurobiology of ancient humans and animals. To begin with we embarked upon an examination of sural nerves, vent...

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Autores principales:	Appenzeller,Otto, Hoyle,Charles V., Santoro,Calogero M., Appenzeller,Martin
Lenguaje:	English
Publicado:	Universidad de Tarapacá. Facultad de Ciencias Sociales y Jurídicas. Departamento de Antropología 2000
Materias:	Sural nerves perivascular cutaneous nerves glycosylated neurochemicals
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-73562000000100016
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spelling	oai:scielo:S0717-735620000001000162006-01-04PALEONEUROBIOLOGYAppenzeller,OttoHoyle,Charles V.Santoro,Calogero M.Appenzeller,Martin Sural nerves perivascular cutaneous nerves glycosylated neurochemicals Paleopathology has, with few exceptions, not identified diseases of the nervous system. We use the term Paleoneurobiology to encompass a branch of knowledge concerned with the study of the neurobiology of ancient humans and animals. To begin with we embarked upon an examination of sural nerves, ventral spinal roots, cutaneous perivascular nerves and glycosylated hemoglobin. Samples of the aforementioned were taken from mummified remains in Egypt (2.000-3.500 years BP) and the Atacama Desert (1000-3000 years BP), and the specific results for each will be presented. The preservation of neurochemicals for millennia in sural nerves opens the possibility to asses the presence of peripheral nerve disease in ancient civilizations. Although the significance of neurochemicals in ventral spinal roots remains to be determined the possibility that these might be involved in some neurologic disorders needs to be explored. Perivascular cutaneous nerve preservation suggest that intraepidermal nerve fibers may also be demonstrable in ancient skin. These fibers have been shown to be importantly affected in peripheral neuropathies. The possibility to establish the presence of diabetes mellitus in ancient civilizations by measuring glyocsylated hemoglobin in mummified blood promises to shed light on the genetics of the high incidence of this disease in contemporaneous Native American populationsinfo:eu-repo/semantics/openAccessUniversidad de Tarapacá. Facultad de Ciencias Sociales y Jurídicas. Departamento de AntropologíaChungará (Arica) v.32 n.1 20002000-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-73562000000100016en10.4067/S0717-73562000000100016
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Sural nerves perivascular cutaneous nerves glycosylated neurochemicals
spellingShingle	Sural nerves perivascular cutaneous nerves glycosylated neurochemicals Appenzeller,Otto Hoyle,Charles V. Santoro,Calogero M. Appenzeller,Martin PALEONEUROBIOLOGY
description	Paleopathology has, with few exceptions, not identified diseases of the nervous system. We use the term Paleoneurobiology to encompass a branch of knowledge concerned with the study of the neurobiology of ancient humans and animals. To begin with we embarked upon an examination of sural nerves, ventral spinal roots, cutaneous perivascular nerves and glycosylated hemoglobin. Samples of the aforementioned were taken from mummified remains in Egypt (2.000-3.500 years BP) and the Atacama Desert (1000-3000 years BP), and the specific results for each will be presented. The preservation of neurochemicals for millennia in sural nerves opens the possibility to asses the presence of peripheral nerve disease in ancient civilizations. Although the significance of neurochemicals in ventral spinal roots remains to be determined the possibility that these might be involved in some neurologic disorders needs to be explored. Perivascular cutaneous nerve preservation suggest that intraepidermal nerve fibers may also be demonstrable in ancient skin. These fibers have been shown to be importantly affected in peripheral neuropathies. The possibility to establish the presence of diabetes mellitus in ancient civilizations by measuring glyocsylated hemoglobin in mummified blood promises to shed light on the genetics of the high incidence of this disease in contemporaneous Native American populations
author	Appenzeller,Otto Hoyle,Charles V. Santoro,Calogero M. Appenzeller,Martin
author_facet	Appenzeller,Otto Hoyle,Charles V. Santoro,Calogero M. Appenzeller,Martin
author_sort	Appenzeller,Otto
title	PALEONEUROBIOLOGY
title_short	PALEONEUROBIOLOGY
title_full	PALEONEUROBIOLOGY
title_fullStr	PALEONEUROBIOLOGY
title_full_unstemmed	PALEONEUROBIOLOGY
title_sort	paleoneurobiology
publisher	Universidad de Tarapacá. Facultad de Ciencias Sociales y Jurídicas. Departamento de Antropología
publishDate	2000
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-73562000000100016
work_keys_str_mv	AT appenzellerotto paleoneurobiology AT hoylecharlesv paleoneurobiology AT santorocalogerom paleoneurobiology AT appenzellermartin paleoneurobiology
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PALEONEUROBIOLOGY

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