Clinical and laboratory characteristics of cirrhotic patients associated with moderate and severe malnutrition

Context and objective: Protein-energy malnutrition is described Context and objective: Protein-energy malnutrition is described in 25-100% of patients with cirrhosis. The aim of this study was to evaluate the nutritional status of cirrhotic patients, to identify clinical and laboratory variables ass...

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Autores principales:	Barcelos,Samantha Thifani Alrutz, Dantas-Corrêa,Esther Buzaglo, Alencar,Maria Luiza Aires, Schiavon,Leonardo de Lucca, Narciso-Schiavon,Janaina Luz
Lenguaje:	English
Publicado:	Sociedad Chilena de Nutrición, Bromatología y Toxicología 2014
Materias:	Liver cirrhosis lymphocyte count malnutrition nutrition assessment serum albumin
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182014000200003
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spelling	oai:scielo:S0717-751820140002000032014-11-10Clinical and laboratory characteristics of cirrhotic patients associated with moderate and severe malnutritionBarcelos,Samantha Thifani AlrutzDantas-Corrêa,Esther BuzagloAlencar,Maria Luiza AiresSchiavon,Leonardo de LuccaNarciso-Schiavon,Janaina Luz Liver cirrhosis lymphocyte count malnutrition nutrition assessment serum albumin Context and objective: Protein-energy malnutrition is described Context and objective: Protein-energy malnutrition is described in 25-100% of patients with cirrhosis. The aim of this study was to evaluate the nutritional status of cirrhotic patients, to identify clinical and laboratory variables associated with moderate to severe malnutrition and to correlate them with cirrhosis prognostic factors (Child-Pugh Classification). Design and setting: This cross-sectional study evaluated cirrhotic individuals admitted to University Hospital from December 2011 to August 2012. Methods: Nutritional status was evaluated by Subjective Global Assessment (SGA), total lymphocyte count and serum albumin. Bivariate analysis was used to identify variables associated with Child C and with moderate to severe malnutrition in different nutritional classifications. Results: Sixty-seven patients were included (mean age 54.4 ± 11.7 years; 74.6% men). The mean MELD score was 14.5 ± 6.5, and almost 30% of the individuals were classified as Child C. With respect to nutritional status, 20.9% showed severe malnutrition by SGA, 14.9% malnutrition by total lymphocyte count, and 40.3% by albumin levels. In all methods employed, moderate to severe malnutrition was correlated with Child classification grade C. The rate of moderate to severe malnutrition by SGA was lower than that evidenced by laboratory methods. Nevertheless, SGA indicated a greater proportion of Child C patients with moderate to severe malnutrition. Conclusion: Due to the high prevalence of malnutrition and its correlation to the severity of cirrhosis, the nutritional evaluation ofcirrhotic patients is an essential step that can be performed through simple methods in routine hospital care.info:eu-repo/semantics/openAccessSociedad Chilena de Nutrición, Bromatología y ToxicologíaRevista chilena de nutrición v.41 n.2 20142014-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182014000200003en10.4067/S0717-75182014000200003
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Liver cirrhosis lymphocyte count malnutrition nutrition assessment serum albumin
spellingShingle	Liver cirrhosis lymphocyte count malnutrition nutrition assessment serum albumin Barcelos,Samantha Thifani Alrutz Dantas-Corrêa,Esther Buzaglo Alencar,Maria Luiza Aires Schiavon,Leonardo de Lucca Narciso-Schiavon,Janaina Luz Clinical and laboratory characteristics of cirrhotic patients associated with moderate and severe malnutrition
description	Context and objective: Protein-energy malnutrition is described Context and objective: Protein-energy malnutrition is described in 25-100% of patients with cirrhosis. The aim of this study was to evaluate the nutritional status of cirrhotic patients, to identify clinical and laboratory variables associated with moderate to severe malnutrition and to correlate them with cirrhosis prognostic factors (Child-Pugh Classification). Design and setting: This cross-sectional study evaluated cirrhotic individuals admitted to University Hospital from December 2011 to August 2012. Methods: Nutritional status was evaluated by Subjective Global Assessment (SGA), total lymphocyte count and serum albumin. Bivariate analysis was used to identify variables associated with Child C and with moderate to severe malnutrition in different nutritional classifications. Results: Sixty-seven patients were included (mean age 54.4 ± 11.7 years; 74.6% men). The mean MELD score was 14.5 ± 6.5, and almost 30% of the individuals were classified as Child C. With respect to nutritional status, 20.9% showed severe malnutrition by SGA, 14.9% malnutrition by total lymphocyte count, and 40.3% by albumin levels. In all methods employed, moderate to severe malnutrition was correlated with Child classification grade C. The rate of moderate to severe malnutrition by SGA was lower than that evidenced by laboratory methods. Nevertheless, SGA indicated a greater proportion of Child C patients with moderate to severe malnutrition. Conclusion: Due to the high prevalence of malnutrition and its correlation to the severity of cirrhosis, the nutritional evaluation ofcirrhotic patients is an essential step that can be performed through simple methods in routine hospital care.
author	Barcelos,Samantha Thifani Alrutz Dantas-Corrêa,Esther Buzaglo Alencar,Maria Luiza Aires Schiavon,Leonardo de Lucca Narciso-Schiavon,Janaina Luz
author_facet	Barcelos,Samantha Thifani Alrutz Dantas-Corrêa,Esther Buzaglo Alencar,Maria Luiza Aires Schiavon,Leonardo de Lucca Narciso-Schiavon,Janaina Luz
author_sort	Barcelos,Samantha Thifani Alrutz
title	Clinical and laboratory characteristics of cirrhotic patients associated with moderate and severe malnutrition
title_short	Clinical and laboratory characteristics of cirrhotic patients associated with moderate and severe malnutrition
title_full	Clinical and laboratory characteristics of cirrhotic patients associated with moderate and severe malnutrition
title_fullStr	Clinical and laboratory characteristics of cirrhotic patients associated with moderate and severe malnutrition
title_full_unstemmed	Clinical and laboratory characteristics of cirrhotic patients associated with moderate and severe malnutrition
title_sort	clinical and laboratory characteristics of cirrhotic patients associated with moderate and severe malnutrition
publisher	Sociedad Chilena de Nutrición, Bromatología y Toxicología
publishDate	2014
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182014000200003
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Clinical and laboratory characteristics of cirrhotic patients associated with moderate and severe malnutrition

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