Anti-proliferative effect of terpenes on human prostate cancer cells: Natural sources and their potential role as chemopreventive agents
ABSTRACT Prostate cancer is one of the neoplastic diseases with the highest morbidity and mortality in the world. The diversity of available treatments and side effects related to therapeutic treatments are severe and affect a patient's quality of life. Thus, to creating new therapeutic alterna...
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Sociedad Chilena de Nutrición, Bromatología y Toxicología
2017
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oai:scielo:S0717-751820170004003712017-12-05Anti-proliferative effect of terpenes on human prostate cancer cells: Natural sources and their potential role as chemopreventive agentsMatus,María FranciscaJorquera-Román,ManuelZúñiga-Hernández,Jessica Prostate cancer Plant secondary metabolites Terpenoids antiproliferation Chemoprevention ABSTRACT Prostate cancer is one of the neoplastic diseases with the highest morbidity and mortality in the world. The diversity of available treatments and side effects related to therapeutic treatments are severe and affect a patient's quality of life. Thus, to creating new therapeutic alternatives to reduce morbidity and creating safe and effective therapies is a constant challenge. Recently, the use of traditional medicine and chemoprevention has gained importance. Several clinical and epidemiological studies suggest that a high-terpenoid compound-based diet is associated with a reduced risk of prostate cancer. This review is focused on the anti-proliferative effects of different terpenoids isolated from natural sources on human prostate cancer cells, with the aim of setting the basis to use these compounds as phytotherapeutic, nutraceutical and functional ingredients.info:eu-repo/semantics/openAccessSociedad Chilena de Nutrición, Bromatología y ToxicologíaRevista chilena de nutrición v.44 n.4 20172017-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182017000400371en10.4067/s0717-75182017000400371 |
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Scielo Chile |
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Scielo Chile |
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topic |
Prostate cancer Plant secondary metabolites Terpenoids antiproliferation Chemoprevention |
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Prostate cancer Plant secondary metabolites Terpenoids antiproliferation Chemoprevention Matus,María Francisca Jorquera-Román,Manuel Zúñiga-Hernández,Jessica Anti-proliferative effect of terpenes on human prostate cancer cells: Natural sources and their potential role as chemopreventive agents |
description |
ABSTRACT Prostate cancer is one of the neoplastic diseases with the highest morbidity and mortality in the world. The diversity of available treatments and side effects related to therapeutic treatments are severe and affect a patient's quality of life. Thus, to creating new therapeutic alternatives to reduce morbidity and creating safe and effective therapies is a constant challenge. Recently, the use of traditional medicine and chemoprevention has gained importance. Several clinical and epidemiological studies suggest that a high-terpenoid compound-based diet is associated with a reduced risk of prostate cancer. This review is focused on the anti-proliferative effects of different terpenoids isolated from natural sources on human prostate cancer cells, with the aim of setting the basis to use these compounds as phytotherapeutic, nutraceutical and functional ingredients. |
author |
Matus,María Francisca Jorquera-Román,Manuel Zúñiga-Hernández,Jessica |
author_facet |
Matus,María Francisca Jorquera-Román,Manuel Zúñiga-Hernández,Jessica |
author_sort |
Matus,María Francisca |
title |
Anti-proliferative effect of terpenes on human prostate cancer cells: Natural sources and their potential role as chemopreventive agents |
title_short |
Anti-proliferative effect of terpenes on human prostate cancer cells: Natural sources and their potential role as chemopreventive agents |
title_full |
Anti-proliferative effect of terpenes on human prostate cancer cells: Natural sources and their potential role as chemopreventive agents |
title_fullStr |
Anti-proliferative effect of terpenes on human prostate cancer cells: Natural sources and their potential role as chemopreventive agents |
title_full_unstemmed |
Anti-proliferative effect of terpenes on human prostate cancer cells: Natural sources and their potential role as chemopreventive agents |
title_sort |
anti-proliferative effect of terpenes on human prostate cancer cells: natural sources and their potential role as chemopreventive agents |
publisher |
Sociedad Chilena de Nutrición, Bromatología y Toxicología |
publishDate |
2017 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182017000400371 |
work_keys_str_mv |
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_version_ |
1718443689764716544 |