The relationship between chronic inflammation associated with obesity and vitamin D deficiency

SUMMARY Obesity is characterized by an abnormal production of adipocytokines, generating chronic inflammation associated in turn with endothelial dysfunction, atherosclerosis and insulin resistance. On the other hand, it is a risk factor for vitamin D deficiency, thus establishing an inverse relatio...

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Autores principales:	Guzmán,Carla, Fredes,Paula, Manterola,Carlos
Lenguaje:	English
Publicado:	Sociedad Chilena de Nutrición, Bromatología y Toxicología 2019
Materias:	Adipocytokines Adipose tissue Calcitriol Chronic inflammation Obesity Vitamin D
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182019000500622
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spelling	oai:scielo:S0717-751820190005006222019-09-16The relationship between chronic inflammation associated with obesity and vitamin D deficiencyGuzmán,CarlaFredes,PaulaManterola,Carlos Adipocytokines Adipose tissue Calcitriol Chronic inflammation Obesity Vitamin D SUMMARY Obesity is characterized by an abnormal production of adipocytokines, generating chronic inflammation associated in turn with endothelial dysfunction, atherosclerosis and insulin resistance. On the other hand, it is a risk factor for vitamin D deficiency, thus establishing an inverse relationship between the plasma levels of this nutrient and acute phase proteins with low vitamin D levels, being able to boost the inflammatory response in obesity. In this context, the correction of poor vitamin D status could be an effective addition to the treatment of obesity; however, evidence of future trials that can support the regulatory effects of supplementation is required. The objective of this review is to analyze the existing evidence and establish the relationship between plasma levels of vitamin D and chronic inflammation associated with obesity. The methodology consists of a sensitive search in the PubMed and Trip Database, limiting the search to articles in English and Spanish published through January 2019. Priority was given to clinical trials, original articles and systematic reviews, from which other relevant research was identified.info:eu-repo/semantics/openAccessSociedad Chilena de Nutrición, Bromatología y ToxicologíaRevista chilena de nutrición v.46 n.5 20192019-10-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182019000500622en10.4067/S0717-75182019000500622
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Adipocytokines Adipose tissue Calcitriol Chronic inflammation Obesity Vitamin D
spellingShingle	Adipocytokines Adipose tissue Calcitriol Chronic inflammation Obesity Vitamin D Guzmán,Carla Fredes,Paula Manterola,Carlos The relationship between chronic inflammation associated with obesity and vitamin D deficiency
description	SUMMARY Obesity is characterized by an abnormal production of adipocytokines, generating chronic inflammation associated in turn with endothelial dysfunction, atherosclerosis and insulin resistance. On the other hand, it is a risk factor for vitamin D deficiency, thus establishing an inverse relationship between the plasma levels of this nutrient and acute phase proteins with low vitamin D levels, being able to boost the inflammatory response in obesity. In this context, the correction of poor vitamin D status could be an effective addition to the treatment of obesity; however, evidence of future trials that can support the regulatory effects of supplementation is required. The objective of this review is to analyze the existing evidence and establish the relationship between plasma levels of vitamin D and chronic inflammation associated with obesity. The methodology consists of a sensitive search in the PubMed and Trip Database, limiting the search to articles in English and Spanish published through January 2019. Priority was given to clinical trials, original articles and systematic reviews, from which other relevant research was identified.
author	Guzmán,Carla Fredes,Paula Manterola,Carlos
author_facet	Guzmán,Carla Fredes,Paula Manterola,Carlos
author_sort	Guzmán,Carla
title	The relationship between chronic inflammation associated with obesity and vitamin D deficiency
title_short	The relationship between chronic inflammation associated with obesity and vitamin D deficiency
title_full	The relationship between chronic inflammation associated with obesity and vitamin D deficiency
title_fullStr	The relationship between chronic inflammation associated with obesity and vitamin D deficiency
title_full_unstemmed	The relationship between chronic inflammation associated with obesity and vitamin D deficiency
title_sort	relationship between chronic inflammation associated with obesity and vitamin d deficiency
publisher	Sociedad Chilena de Nutrición, Bromatología y Toxicología
publishDate	2019
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182019000500622
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The relationship between chronic inflammation associated with obesity and vitamin D deficiency

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