Glomerular filtration rate and its relationship with visceral and subcutaneous adiposity: a study with patients from Northeast Brazil

ABSTRACT Objective: evaluate the relationship between visceral/subcutaneous adipose tissue (VAT/SAT) and glomerular filtration rate (GFR). Methods: A case series study was conducted with 146 male and female adult outpatients at a hospital in Northeast Brazil. VAT and SAT were quantified using comp...

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Autores principales:	Campello Leal,Claudia, Galvão Rodrigues,Isa, Leite,Ana Paula Dornellas Leão, Arruda,Ilma Kruze Grande De, Diniz,Alcides da Silva, Pinho,Claudia Porto Sabino, Coelho Cabral,Poliana
Lenguaje:	English
Publicado:	Sociedad Chilena de Nutrición, Bromatología y Toxicología 2020
Materias:	Abdominal obesity Glomerular filtration rate Kidney disease Visceral fat
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182020000300449
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spelling	oai:scielo:S0717-751820200003004492020-06-22Glomerular filtration rate and its relationship with visceral and subcutaneous adiposity: a study with patients from Northeast BrazilCampello Leal,ClaudiaGalvão Rodrigues,IsaLeite,Ana Paula Dornellas LeãoArruda,Ilma Kruze Grande DeDiniz,Alcides da SilvaPinho,Claudia Porto SabinoCoelho Cabral,Poliana Abdominal obesity Glomerular filtration rate Kidney disease Visceral fat ABSTRACT Objective: evaluate the relationship between visceral/subcutaneous adipose tissue (VAT/SAT) and glomerular filtration rate (GFR). Methods: A case series study was conducted with 146 male and female adult outpatients at a hospital in Northeast Brazil. VAT and SAT were quantified using computed tomography and GFR was estimated using the formula proposed by the CKD Epidemiology Collaboration. The conceptual model also considered socio-demographic, clinical, anthropometric and lifestyle variables. Results: Females accounted for 71.9% of the sample and mean age was 52.5±13.2 years. Mean body mass index indicated obesity in both sexes (men:30.4±5.9 kg/m2; women: 31.6±6.1 kg/m2). For the same mean age and BMI, men had more VAT and a higher VAT/SAT ratio. Mean GFR was similar between sexes and within the normal range. Simple linear regression analysis revealed that 21.8% of the reduction in GFR in males could be explained by the VAT/SAT ratio (p=0.002). Among females, both VAT alone and the VAT/SAT ratio were predictors of GFR reduction (r2=4.8%, p=0.025 and r2=5.3%, p=0.019, respectively). Conclusion: Mean VAT and VAT/SAT ratio were compatible with abdominal obesity in both sexes and were related to a reduction in GFR.info:eu-repo/semantics/openAccessSociedad Chilena de Nutrición, Bromatología y ToxicologíaRevista chilena de nutrición v.47 n.3 20202020-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182020000300449en10.4067/S0717-75182020000300449
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Abdominal obesity Glomerular filtration rate Kidney disease Visceral fat
spellingShingle	Abdominal obesity Glomerular filtration rate Kidney disease Visceral fat Campello Leal,Claudia Galvão Rodrigues,Isa Leite,Ana Paula Dornellas Leão Arruda,Ilma Kruze Grande De Diniz,Alcides da Silva Pinho,Claudia Porto Sabino Coelho Cabral,Poliana Glomerular filtration rate and its relationship with visceral and subcutaneous adiposity: a study with patients from Northeast Brazil
description	ABSTRACT Objective: evaluate the relationship between visceral/subcutaneous adipose tissue (VAT/SAT) and glomerular filtration rate (GFR). Methods: A case series study was conducted with 146 male and female adult outpatients at a hospital in Northeast Brazil. VAT and SAT were quantified using computed tomography and GFR was estimated using the formula proposed by the CKD Epidemiology Collaboration. The conceptual model also considered socio-demographic, clinical, anthropometric and lifestyle variables. Results: Females accounted for 71.9% of the sample and mean age was 52.5±13.2 years. Mean body mass index indicated obesity in both sexes (men:30.4±5.9 kg/m2; women: 31.6±6.1 kg/m2). For the same mean age and BMI, men had more VAT and a higher VAT/SAT ratio. Mean GFR was similar between sexes and within the normal range. Simple linear regression analysis revealed that 21.8% of the reduction in GFR in males could be explained by the VAT/SAT ratio (p=0.002). Among females, both VAT alone and the VAT/SAT ratio were predictors of GFR reduction (r2=4.8%, p=0.025 and r2=5.3%, p=0.019, respectively). Conclusion: Mean VAT and VAT/SAT ratio were compatible with abdominal obesity in both sexes and were related to a reduction in GFR.
author	Campello Leal,Claudia Galvão Rodrigues,Isa Leite,Ana Paula Dornellas Leão Arruda,Ilma Kruze Grande De Diniz,Alcides da Silva Pinho,Claudia Porto Sabino Coelho Cabral,Poliana
author_facet	Campello Leal,Claudia Galvão Rodrigues,Isa Leite,Ana Paula Dornellas Leão Arruda,Ilma Kruze Grande De Diniz,Alcides da Silva Pinho,Claudia Porto Sabino Coelho Cabral,Poliana
author_sort	Campello Leal,Claudia
title	Glomerular filtration rate and its relationship with visceral and subcutaneous adiposity: a study with patients from Northeast Brazil
title_short	Glomerular filtration rate and its relationship with visceral and subcutaneous adiposity: a study with patients from Northeast Brazil
title_full	Glomerular filtration rate and its relationship with visceral and subcutaneous adiposity: a study with patients from Northeast Brazil
title_fullStr	Glomerular filtration rate and its relationship with visceral and subcutaneous adiposity: a study with patients from Northeast Brazil
title_full_unstemmed	Glomerular filtration rate and its relationship with visceral and subcutaneous adiposity: a study with patients from Northeast Brazil
title_sort	glomerular filtration rate and its relationship with visceral and subcutaneous adiposity: a study with patients from northeast brazil
publisher	Sociedad Chilena de Nutrición, Bromatología y Toxicología
publishDate	2020
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-75182020000300449
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Glomerular filtration rate and its relationship with visceral and subcutaneous adiposity: a study with patients from Northeast Brazil

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