Toxocara canis: migración larval y eosinofilia en el hospedador paraténico

The objective of this study was to analize the migratory behaviour of larvae of Toxocara canis related to eosinophilia in paratenic hosts. Mice were used as experimental models. In rodents and humans the migratory route and the pathogenesis of the parasite are similar. Balb/c mice were inoculated in...

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Autores principales:	DEL VALLE GUARDIS,MÓNICA, RADMAN,NILDA E, BURGOS,LOLA, FONROUGE,REINALDO D, ARCHELLI,SUSANA M.
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Chilena de Parasitología 2002
Materias:	Toxocara canis eosinophilia experimental model paratenic host
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-77122002000100011
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spelling	oai:scielo:S0717-771220020001000112005-09-29Toxocara canis: migración larval y eosinofilia en el hospedador paraténicoDEL VALLE GUARDIS,MÓNICARADMAN,NILDA EBURGOS,LOLAFONROUGE,REINALDO DARCHELLI,SUSANA M. Toxocara canis eosinophilia experimental model paratenic host The objective of this study was to analize the migratory behaviour of larvae of Toxocara canis related to eosinophilia in paratenic hosts. Mice were used as experimental models. In rodents and humans the migratory route and the pathogenesis of the parasite are similar. Balb/c mice were inoculated intragastrically with 250 (± 10) embryonated eggs. Larvae recovery: eyes and encephalon were chosen as reference organs. In the encephalon and the eye, larval recovery began in the forth and twelfth day post-inoculation respectively. The association measured by the correlation coefficient between time of observation and recovered larvae in each organ was: right eye (RE) r= 0.24; left eye (LE) r= 0.43; encephalon (E) r= 0.60. The recovery of inoculated larvae is significantly higher in the encephalon than in the eyeballs (Chi square: 185; p < 0.00001), in 80 % of mice eosinophils exceeded 6% of the formula. The correlation between eosinophilia and larval recovery in the organs observed was: 0.33 for the right eye (RE); 0.21 for the left eye (LE) and 0.44 for the encephalon; these correlation values are considered low, suggesting no association between eosinophilia and the quantity of T. canis larvae lodged in the eyes (ocular toxocarosis) or in the encephalon (cerebrospinal toxocarosis).info:eu-repo/semantics/openAccessSociedad Chilena de ParasitologíaParasitología latinoamericana v.57 n.1-2 20022002-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-77122002000100011es10.4067/S0717-77122002000100011
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Toxocara canis eosinophilia experimental model paratenic host
spellingShingle	Toxocara canis eosinophilia experimental model paratenic host DEL VALLE GUARDIS,MÓNICA RADMAN,NILDA E BURGOS,LOLA FONROUGE,REINALDO D ARCHELLI,SUSANA M. Toxocara canis: migración larval y eosinofilia en el hospedador paraténico
description	The objective of this study was to analize the migratory behaviour of larvae of Toxocara canis related to eosinophilia in paratenic hosts. Mice were used as experimental models. In rodents and humans the migratory route and the pathogenesis of the parasite are similar. Balb/c mice were inoculated intragastrically with 250 (± 10) embryonated eggs. Larvae recovery: eyes and encephalon were chosen as reference organs. In the encephalon and the eye, larval recovery began in the forth and twelfth day post-inoculation respectively. The association measured by the correlation coefficient between time of observation and recovered larvae in each organ was: right eye (RE) r= 0.24; left eye (LE) r= 0.43; encephalon (E) r= 0.60. The recovery of inoculated larvae is significantly higher in the encephalon than in the eyeballs (Chi square: 185; p < 0.00001), in 80 % of mice eosinophils exceeded 6% of the formula. The correlation between eosinophilia and larval recovery in the organs observed was: 0.33 for the right eye (RE); 0.21 for the left eye (LE) and 0.44 for the encephalon; these correlation values are considered low, suggesting no association between eosinophilia and the quantity of T. canis larvae lodged in the eyes (ocular toxocarosis) or in the encephalon (cerebrospinal toxocarosis).
author	DEL VALLE GUARDIS,MÓNICA RADMAN,NILDA E BURGOS,LOLA FONROUGE,REINALDO D ARCHELLI,SUSANA M.
author_facet	DEL VALLE GUARDIS,MÓNICA RADMAN,NILDA E BURGOS,LOLA FONROUGE,REINALDO D ARCHELLI,SUSANA M.
author_sort	DEL VALLE GUARDIS,MÓNICA
title	Toxocara canis: migración larval y eosinofilia en el hospedador paraténico
title_short	Toxocara canis: migración larval y eosinofilia en el hospedador paraténico
title_full	Toxocara canis: migración larval y eosinofilia en el hospedador paraténico
title_fullStr	Toxocara canis: migración larval y eosinofilia en el hospedador paraténico
title_full_unstemmed	Toxocara canis: migración larval y eosinofilia en el hospedador paraténico
title_sort	toxocara canis: migración larval y eosinofilia en el hospedador paraténico
publisher	Sociedad Chilena de Parasitología
publishDate	2002
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-77122002000100011
work_keys_str_mv	AT delvalleguardismonica toxocaracanismigracionlarvalyeosinofiliaenelhospedadorparatenico AT radmannildae toxocaracanismigracionlarvalyeosinofiliaenelhospedadorparatenico AT burgoslola toxocaracanismigracionlarvalyeosinofiliaenelhospedadorparatenico AT fonrougereinaldod toxocaracanismigracionlarvalyeosinofiliaenelhospedadorparatenico AT archellisusanam toxocaracanismigracionlarvalyeosinofiliaenelhospedadorparatenico
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Toxocara canis: migración larval y eosinofilia en el hospedador paraténico

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