Toxoplasmose em coelhos: comparação do perfil bioquímico hepático com os achados patológicos em infecção pelo Toxoplasma gondii

To determine the hepatic profiles due to Toxoplasma gondii infection in rabbits, 15 animals were divided in three groups of five animals each. The first and second groups were inoculated subcutaneously with 10(6) and 10³ tachyzoites of T. gondii respectively, while the third was left as control. Blo...

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Autores principales:	DIAS MUNHOZ,ALEXANDRE, REGO SOUZA PINTO,ALEXANDRE, RÊGO ALBUQUERQUE,GEORGE, RODRIGUES DE OLIVEIRA,FRANCISCO CARLOS, GIACOMO LOSS,ZELSON, GOMES LOPES,CARLOS WILSON
Lenguaje:	Portuguese
Publicado:	Sociedad Chilena de Parasitología 2002
Materias:	Toxoplasma gondii Toxoplasmosis Perfil Bioquímico hepatico Coelhos
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-77122002000300001
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spelling	oai:scielo:S0717-771220020003000012003-02-06Toxoplasmose em coelhos: comparação do perfil bioquímico hepático com os achados patológicos em infecção pelo Toxoplasma gondiiDIAS MUNHOZ,ALEXANDREREGO SOUZA PINTO,ALEXANDRERÊGO ALBUQUERQUE,GEORGERODRIGUES DE OLIVEIRA,FRANCISCO CARLOSGIACOMO LOSS,ZELSONGOMES LOPES,CARLOS WILSON Toxoplasma gondii Toxoplasmosis Perfil Bioquímico hepatico Coelhos To determine the hepatic profiles due to Toxoplasma gondii infection in rabbits, 15 animals were divided in three groups of five animals each. The first and second groups were inoculated subcutaneously with 10(6) and 10³ tachyzoites of T. gondii respectively, while the third was left as control. Blood samples were taken on days 0, 4, 8, e 11 after inoculation (DAI). Livers of each rabbit was analyzed in other to observed lesions. Hepathomegaly was observed in all of the infected groups, independently of the dose used, where was observed a significant increase of AST e ALT at 8th DAI. Tachyzoites were observed in all infected animals, and were reisolated in 90% of livers bioassed in mice. Histopathology was consisted by diffuse infiltration inflammatory, consisted mainly by lymphocytes at sinusoids e portal space. The increase of AST and ALT during acute toxoplasmosis in rabbits was justified by presence of tachyzoites in tissue smears associated with gross and histopathologic lesionsinfo:eu-repo/semantics/openAccessSociedad Chilena de ParasitologíaParasitología latinoamericana v.57 n.3-4 20022002-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-77122002000300001pt10.4067/S0717-77122002000300001
institution	Scielo Chile
collection	Scielo Chile
language	Portuguese
topic	Toxoplasma gondii Toxoplasmosis Perfil Bioquímico hepatico Coelhos
spellingShingle	Toxoplasma gondii Toxoplasmosis Perfil Bioquímico hepatico Coelhos DIAS MUNHOZ,ALEXANDRE REGO SOUZA PINTO,ALEXANDRE RÊGO ALBUQUERQUE,GEORGE RODRIGUES DE OLIVEIRA,FRANCISCO CARLOS GIACOMO LOSS,ZELSON GOMES LOPES,CARLOS WILSON Toxoplasmose em coelhos: comparação do perfil bioquímico hepático com os achados patológicos em infecção pelo Toxoplasma gondii
description	To determine the hepatic profiles due to Toxoplasma gondii infection in rabbits, 15 animals were divided in three groups of five animals each. The first and second groups were inoculated subcutaneously with 10(6) and 10³ tachyzoites of T. gondii respectively, while the third was left as control. Blood samples were taken on days 0, 4, 8, e 11 after inoculation (DAI). Livers of each rabbit was analyzed in other to observed lesions. Hepathomegaly was observed in all of the infected groups, independently of the dose used, where was observed a significant increase of AST e ALT at 8th DAI. Tachyzoites were observed in all infected animals, and were reisolated in 90% of livers bioassed in mice. Histopathology was consisted by diffuse infiltration inflammatory, consisted mainly by lymphocytes at sinusoids e portal space. The increase of AST and ALT during acute toxoplasmosis in rabbits was justified by presence of tachyzoites in tissue smears associated with gross and histopathologic lesions
author	DIAS MUNHOZ,ALEXANDRE REGO SOUZA PINTO,ALEXANDRE RÊGO ALBUQUERQUE,GEORGE RODRIGUES DE OLIVEIRA,FRANCISCO CARLOS GIACOMO LOSS,ZELSON GOMES LOPES,CARLOS WILSON
author_facet	DIAS MUNHOZ,ALEXANDRE REGO SOUZA PINTO,ALEXANDRE RÊGO ALBUQUERQUE,GEORGE RODRIGUES DE OLIVEIRA,FRANCISCO CARLOS GIACOMO LOSS,ZELSON GOMES LOPES,CARLOS WILSON
author_sort	DIAS MUNHOZ,ALEXANDRE
title	Toxoplasmose em coelhos: comparação do perfil bioquímico hepático com os achados patológicos em infecção pelo Toxoplasma gondii
title_short	Toxoplasmose em coelhos: comparação do perfil bioquímico hepático com os achados patológicos em infecção pelo Toxoplasma gondii
title_full	Toxoplasmose em coelhos: comparação do perfil bioquímico hepático com os achados patológicos em infecção pelo Toxoplasma gondii
title_fullStr	Toxoplasmose em coelhos: comparação do perfil bioquímico hepático com os achados patológicos em infecção pelo Toxoplasma gondii
title_full_unstemmed	Toxoplasmose em coelhos: comparação do perfil bioquímico hepático com os achados patológicos em infecção pelo Toxoplasma gondii
title_sort	toxoplasmose em coelhos: comparação do perfil bioquímico hepático com os achados patológicos em infecção pelo toxoplasma gondii
publisher	Sociedad Chilena de Parasitología
publishDate	2002
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-77122002000300001
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Toxoplasmose em coelhos: comparação do perfil bioquímico hepático com os achados patológicos em infecção pelo Toxoplasma gondii

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