Sexo del hospedero y dosis infectante de parásitos como factores en el desarrollo de la infección con Trypanosoma cruzi en un modelo murino

Male and female mice of ACA strain were infected with 200 and 2,000 bloodstream trypomastigotes from Dm 28c clone of Trypanosoma cruzi. All the animals were susceptible to the infection regardless of their sex and dose of initial inoculum used. Both male and female, infected with 2,000 parasites sho...

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Autores principales:	URZÚA,CONSTANZA, MORALES,MARÍA ANGÉLICA, VERGARA,ULISES, PALAU,MARÍA TERESA, ZÚÑIGA,CLAUDIO
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad Chilena de Parasitología 2004
Materias:	Experimental Chagas'disease Trypanosoma cruzi Murine trypanosomiosis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-77122004000300003
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id	oai:scielo:S0717-77122004000300003
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spelling	oai:scielo:S0717-771220040003000032005-01-26Sexo del hospedero y dosis infectante de parásitos como factores en el desarrollo de la infección con Trypanosoma cruzi en un modelo murinoURZÚA,CONSTANZAMORALES,MARÍA ANGÉLICAVERGARA,ULISESPALAU,MARÍA TERESAZÚÑIGA,CLAUDIO Experimental Chagas'disease Trypanosoma cruzi Murine trypanosomiosis Male and female mice of ACA strain were infected with 200 and 2,000 bloodstream trypomastigotes from Dm 28c clone of Trypanosoma cruzi. All the animals were susceptible to the infection regardless of their sex and dose of initial inoculum used. Both male and female, infected with 2,000 parasites showed significantly higher level of parasitemia than mice infected with the lower dose. At the same time, males developed higher parasitemia level than females, when they were infected with both 200 and 2,000 parasites. Despite of experimental animals behaved as susceptible, the survival period was significantly longer in males infected with 200 trypomastigotes when compared to males infected with 2,000 parasites. Females infected with 2,000 survive a longer time than males infected with the same dose of parasites. No significant differences were observed during the survival period when comparing females infected with 200 and 2,000 parasites, neither in the case of male and female infected with 200 parasites. Apparently, the parasitemia level is the main characteristic affected by the variables sex of the host and initial parasite dose.info:eu-repo/semantics/openAccessSociedad Chilena de ParasitologíaParasitología latinoamericana v.59 n.3-4 20042004-07-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-77122004000300003es10.4067/S0717-77122004000300003
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	Experimental Chagas'disease Trypanosoma cruzi Murine trypanosomiosis
spellingShingle	Experimental Chagas'disease Trypanosoma cruzi Murine trypanosomiosis URZÚA,CONSTANZA MORALES,MARÍA ANGÉLICA VERGARA,ULISES PALAU,MARÍA TERESA ZÚÑIGA,CLAUDIO Sexo del hospedero y dosis infectante de parásitos como factores en el desarrollo de la infección con Trypanosoma cruzi en un modelo murino
description	Male and female mice of ACA strain were infected with 200 and 2,000 bloodstream trypomastigotes from Dm 28c clone of Trypanosoma cruzi. All the animals were susceptible to the infection regardless of their sex and dose of initial inoculum used. Both male and female, infected with 2,000 parasites showed significantly higher level of parasitemia than mice infected with the lower dose. At the same time, males developed higher parasitemia level than females, when they were infected with both 200 and 2,000 parasites. Despite of experimental animals behaved as susceptible, the survival period was significantly longer in males infected with 200 trypomastigotes when compared to males infected with 2,000 parasites. Females infected with 2,000 survive a longer time than males infected with the same dose of parasites. No significant differences were observed during the survival period when comparing females infected with 200 and 2,000 parasites, neither in the case of male and female infected with 200 parasites. Apparently, the parasitemia level is the main characteristic affected by the variables sex of the host and initial parasite dose.
author	URZÚA,CONSTANZA MORALES,MARÍA ANGÉLICA VERGARA,ULISES PALAU,MARÍA TERESA ZÚÑIGA,CLAUDIO
author_facet	URZÚA,CONSTANZA MORALES,MARÍA ANGÉLICA VERGARA,ULISES PALAU,MARÍA TERESA ZÚÑIGA,CLAUDIO
author_sort	URZÚA,CONSTANZA
title	Sexo del hospedero y dosis infectante de parásitos como factores en el desarrollo de la infección con Trypanosoma cruzi en un modelo murino
title_short	Sexo del hospedero y dosis infectante de parásitos como factores en el desarrollo de la infección con Trypanosoma cruzi en un modelo murino
title_full	Sexo del hospedero y dosis infectante de parásitos como factores en el desarrollo de la infección con Trypanosoma cruzi en un modelo murino
title_fullStr	Sexo del hospedero y dosis infectante de parásitos como factores en el desarrollo de la infección con Trypanosoma cruzi en un modelo murino
title_full_unstemmed	Sexo del hospedero y dosis infectante de parásitos como factores en el desarrollo de la infección con Trypanosoma cruzi en un modelo murino
title_sort	sexo del hospedero y dosis infectante de parásitos como factores en el desarrollo de la infección con trypanosoma cruzi en un modelo murino
publisher	Sociedad Chilena de Parasitología
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-77122004000300003
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Sexo del hospedero y dosis infectante de parásitos como factores en el desarrollo de la infección con Trypanosoma cruzi en un modelo murino

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