Gliomas de bajo grado: Viejas controversias, nuevas evidencias

Many aspects of the management of low-grade gliomas have been controversial. Warren Mason reviews the new evidence addressing some of them in the article "Advances in the management of low-grade gliomas, published in Can J. Neurol. Sci. 2005". This information should be specially useful fo...

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Autor principal:	Valenzuela M.,Raúl
Lenguaje:	Spanish / Castilian
Publicado:	Sociedad de Neurología, Psiquiatría y Neurocirugía 2005
Materias:	gliomas de baja malignidad oligodendrogliomas astrocitomas tumores cerebrales
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-92272005000300007
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spelling	oai:scielo:S0717-922720050003000072005-09-21Gliomas de bajo grado: Viejas controversias, nuevas evidenciasValenzuela M.,Raúl gliomas de baja malignidad oligodendrogliomas astrocitomas tumores cerebrales Many aspects of the management of low-grade gliomas have been controversial. Warren Mason reviews the new evidence addressing some of them in the article "Advances in the management of low-grade gliomas, published in Can J. Neurol. Sci. 2005". This information should be specially useful for tailoring therapies to each particular situation. The presence of an oligodendroglial component and 1p and 19q deletions confers a better prognosis and better response rates to chemotherapy and radiotherapy. Delaying interventions in stable, asymptomatic patients does not seem to affect overall survival. More extensive resections are associated to longer and better quality survival. Early radiotherapy prolongs time to progression, but not overall survival as compared to delayed radiotherapy. The optimal dose is in the range between 45Gy and less than 59.4 Gy. Chemotherapy produces responses in most of these patientsinfo:eu-repo/semantics/openAccessSociedad de Neurología, Psiquiatría y NeurocirugíaRevista chilena de neuro-psiquiatría v.43 n.3 20052005-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-92272005000300007es10.4067/S0717-92272005000300007
institution	Scielo Chile
collection	Scielo Chile
language	Spanish / Castilian
topic	gliomas de baja malignidad oligodendrogliomas astrocitomas tumores cerebrales
spellingShingle	gliomas de baja malignidad oligodendrogliomas astrocitomas tumores cerebrales Valenzuela M.,Raúl Gliomas de bajo grado: Viejas controversias, nuevas evidencias
description	Many aspects of the management of low-grade gliomas have been controversial. Warren Mason reviews the new evidence addressing some of them in the article "Advances in the management of low-grade gliomas, published in Can J. Neurol. Sci. 2005". This information should be specially useful for tailoring therapies to each particular situation. The presence of an oligodendroglial component and 1p and 19q deletions confers a better prognosis and better response rates to chemotherapy and radiotherapy. Delaying interventions in stable, asymptomatic patients does not seem to affect overall survival. More extensive resections are associated to longer and better quality survival. Early radiotherapy prolongs time to progression, but not overall survival as compared to delayed radiotherapy. The optimal dose is in the range between 45Gy and less than 59.4 Gy. Chemotherapy produces responses in most of these patients
author	Valenzuela M.,Raúl
author_facet	Valenzuela M.,Raúl
author_sort	Valenzuela M.,Raúl
title	Gliomas de bajo grado: Viejas controversias, nuevas evidencias
title_short	Gliomas de bajo grado: Viejas controversias, nuevas evidencias
title_full	Gliomas de bajo grado: Viejas controversias, nuevas evidencias
title_fullStr	Gliomas de bajo grado: Viejas controversias, nuevas evidencias
title_full_unstemmed	Gliomas de bajo grado: Viejas controversias, nuevas evidencias
title_sort	gliomas de bajo grado: viejas controversias, nuevas evidencias
publisher	Sociedad de Neurología, Psiquiatría y Neurocirugía
publishDate	2005
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-92272005000300007
work_keys_str_mv	AT valenzuelamraul gliomasdebajogradoviejascontroversiasnuevasevidencias
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Gliomas de bajo grado: Viejas controversias, nuevas evidencias

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