EFFECTS OF ACETYLSALICYLIC ACID ON ETHANOL-INDUCED INTRAUTERINE GROWTH RESTRICTION IN RATS

SUMMARY: The effects of acetylsalicylic acid (ASA) on intrauterine growth restriction induced by maternal ethanol consumption were studied. A single intraperitoneal dose of ethanol (2.96 g/kg body weight), injected on the 10th day of pregnancy (PD10), significantly reduced maternal weight gain, feta...

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Autores principales: Aparecida Marinho,Sandra, Sala,Miguel Angel, Lopes,Ruberval Armando, de Moraes Grisi,Márcio Fernando, Belém Novaes Jr.,Arthur, Scombatti de Souza,Sérgio Luis, Taba Jr.,Mário
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2003
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Rat
ASA
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022003000200002
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spelling oai:scielo:S0717-950220030002000022005-09-13EFFECTS OF ACETYLSALICYLIC ACID ON ETHANOL-INDUCED INTRAUTERINE GROWTH RESTRICTION IN RATSAparecida Marinho,SandraSala,Miguel AngelLopes,Ruberval Armandode Moraes Grisi,Márcio FernandoBelém Novaes Jr.,ArthurScombatti de Souza,Sérgio LuisTaba Jr.,Mário Rat Fetus ASA Ethanol Intrauterine development SUMMARY: The effects of acetylsalicylic acid (ASA) on intrauterine growth restriction induced by maternal ethanol consumption were studied. A single intraperitoneal dose of ethanol (2.96 g/kg body weight), injected on the 10th day of pregnancy (PD10), significantly reduced maternal weight gain, fetal weight, amniotic fluid volume and umbilical cord length. Meanwhile, ethanol did not affect placental weight or litter size. A single intraperitoneal dose of ASA (200 mg/g body weight), injected on the PD10, did not modify maternal body weight gain, litter size, fetal and placental weights and amniotic fluid volume, but significantly diminished umbilical cord length. Intraperitoneal injections of either ASA (200 mg/g body weight) or ethanol (2.96 g/kg body weight) on the PD10, demonstrated that ASA antagonized, in part at least, the effects of ethanol on maternal weight gain, fetal weight, and amniotic fluid volume. Contrarily, ASA potentiated the effect of ethanol on umbilical cord lengthinfo:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.21 n.2 20032003-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022003000200002en10.4067/S0717-95022003000200002
institution Scielo Chile
collection Scielo Chile
language English
topic Rat
Fetus
ASA
Ethanol
Intrauterine development
spellingShingle Rat
Fetus
ASA
Ethanol
Intrauterine development
Aparecida Marinho,Sandra
Sala,Miguel Angel
Lopes,Ruberval Armando
de Moraes Grisi,Márcio Fernando
Belém Novaes Jr.,Arthur
Scombatti de Souza,Sérgio Luis
Taba Jr.,Mário
EFFECTS OF ACETYLSALICYLIC ACID ON ETHANOL-INDUCED INTRAUTERINE GROWTH RESTRICTION IN RATS
description SUMMARY: The effects of acetylsalicylic acid (ASA) on intrauterine growth restriction induced by maternal ethanol consumption were studied. A single intraperitoneal dose of ethanol (2.96 g/kg body weight), injected on the 10th day of pregnancy (PD10), significantly reduced maternal weight gain, fetal weight, amniotic fluid volume and umbilical cord length. Meanwhile, ethanol did not affect placental weight or litter size. A single intraperitoneal dose of ASA (200 mg/g body weight), injected on the PD10, did not modify maternal body weight gain, litter size, fetal and placental weights and amniotic fluid volume, but significantly diminished umbilical cord length. Intraperitoneal injections of either ASA (200 mg/g body weight) or ethanol (2.96 g/kg body weight) on the PD10, demonstrated that ASA antagonized, in part at least, the effects of ethanol on maternal weight gain, fetal weight, and amniotic fluid volume. Contrarily, ASA potentiated the effect of ethanol on umbilical cord length
author Aparecida Marinho,Sandra
Sala,Miguel Angel
Lopes,Ruberval Armando
de Moraes Grisi,Márcio Fernando
Belém Novaes Jr.,Arthur
Scombatti de Souza,Sérgio Luis
Taba Jr.,Mário
author_facet Aparecida Marinho,Sandra
Sala,Miguel Angel
Lopes,Ruberval Armando
de Moraes Grisi,Márcio Fernando
Belém Novaes Jr.,Arthur
Scombatti de Souza,Sérgio Luis
Taba Jr.,Mário
author_sort Aparecida Marinho,Sandra
title EFFECTS OF ACETYLSALICYLIC ACID ON ETHANOL-INDUCED INTRAUTERINE GROWTH RESTRICTION IN RATS
title_short EFFECTS OF ACETYLSALICYLIC ACID ON ETHANOL-INDUCED INTRAUTERINE GROWTH RESTRICTION IN RATS
title_full EFFECTS OF ACETYLSALICYLIC ACID ON ETHANOL-INDUCED INTRAUTERINE GROWTH RESTRICTION IN RATS
title_fullStr EFFECTS OF ACETYLSALICYLIC ACID ON ETHANOL-INDUCED INTRAUTERINE GROWTH RESTRICTION IN RATS
title_full_unstemmed EFFECTS OF ACETYLSALICYLIC ACID ON ETHANOL-INDUCED INTRAUTERINE GROWTH RESTRICTION IN RATS
title_sort effects of acetylsalicylic acid on ethanol-induced intrauterine growth restriction in rats
publisher Sociedad Chilena de Anatomía
publishDate 2003
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022003000200002
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