HISTOLOGIC ALTERATIONS OF THE BASEMENT MEMBRANE OF THE DERMAL AND EPIDERMAL LAYERS OF THE HOOF IN HORSES WITH ACUTE LAMINITIS

The morphological characteristics of the hooves of two groups of horses were studied. The first group was comprised of six adult animals without any treatment and served as the control. The other group, comprised of seven horses, received carbohydrates overload orally. Of these, 71% developed lamini...

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Autores principales:	de Lima Sampaio,Rita de Cássia, Canola,Julio Carlos, de Lacerda Neto,José Corrêa, de Moraes,Julieta Rodini Engrácia
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2004
Materias:	Basement membrane Equine Laminitis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022004000400012
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spelling	oai:scielo:S0717-950220040004000122005-02-24HISTOLOGIC ALTERATIONS OF THE BASEMENT MEMBRANE OF THE DERMAL AND EPIDERMAL LAYERS OF THE HOOF IN HORSES WITH ACUTE LAMINITISde Lima Sampaio,Rita de CássiaCanola,Julio Carlosde Lacerda Neto,José Corrêade Moraes,Julieta Rodini Engrácia Basement membrane Equine Laminitis The morphological characteristics of the hooves of two groups of horses were studied. The first group was comprised of six adult animals without any treatment and served as the control. The other group, comprised of seven horses, received carbohydrates overload orally. Of these, 71% developed laminitis between 36 and 48 hours after carbohydrate administration. After 48 hours of induction, the animals were sacrificed and their fore limbs and hindlimbs were removed for histologic study. Tissue sections 5 to 7 µm thick were obtained, stained with hematoxylin-eosin (H&E) or periodic acid Schiff's (PAS), and then examined by light microscopy. It was possible to identify in horses from the laminitis group, morphological and structural changes in the architecture of the primary and secondary epidermal lamellae, which were found to be sharpened and elongated with basal cells having round-shaped nuclei and also localized at the basal pole. PAS staining showed that in horses from the control group there were the presence of a basement membrane, separating and outlining the dermal and epidermal lamellae. In the laminitis group horses, there were deformation and fragmentation of the basement membrane. The utilization of PAS permitted the determination of the degenerative alterations in the basement membrane, which occurred early and coincident with the development of clinical signs of lamenessinfo:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.22 n.4 20042004-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022004000400012en10.4067/S0717-95022004000400012
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Basement membrane Equine Laminitis
spellingShingle	Basement membrane Equine Laminitis de Lima Sampaio,Rita de Cássia Canola,Julio Carlos de Lacerda Neto,José Corrêa de Moraes,Julieta Rodini Engrácia HISTOLOGIC ALTERATIONS OF THE BASEMENT MEMBRANE OF THE DERMAL AND EPIDERMAL LAYERS OF THE HOOF IN HORSES WITH ACUTE LAMINITIS
description	The morphological characteristics of the hooves of two groups of horses were studied. The first group was comprised of six adult animals without any treatment and served as the control. The other group, comprised of seven horses, received carbohydrates overload orally. Of these, 71% developed laminitis between 36 and 48 hours after carbohydrate administration. After 48 hours of induction, the animals were sacrificed and their fore limbs and hindlimbs were removed for histologic study. Tissue sections 5 to 7 µm thick were obtained, stained with hematoxylin-eosin (H&E) or periodic acid Schiff's (PAS), and then examined by light microscopy. It was possible to identify in horses from the laminitis group, morphological and structural changes in the architecture of the primary and secondary epidermal lamellae, which were found to be sharpened and elongated with basal cells having round-shaped nuclei and also localized at the basal pole. PAS staining showed that in horses from the control group there were the presence of a basement membrane, separating and outlining the dermal and epidermal lamellae. In the laminitis group horses, there were deformation and fragmentation of the basement membrane. The utilization of PAS permitted the determination of the degenerative alterations in the basement membrane, which occurred early and coincident with the development of clinical signs of lameness
author	de Lima Sampaio,Rita de Cássia Canola,Julio Carlos de Lacerda Neto,José Corrêa de Moraes,Julieta Rodini Engrácia
author_facet	de Lima Sampaio,Rita de Cássia Canola,Julio Carlos de Lacerda Neto,José Corrêa de Moraes,Julieta Rodini Engrácia
author_sort	de Lima Sampaio,Rita de Cássia
title	HISTOLOGIC ALTERATIONS OF THE BASEMENT MEMBRANE OF THE DERMAL AND EPIDERMAL LAYERS OF THE HOOF IN HORSES WITH ACUTE LAMINITIS
title_short	HISTOLOGIC ALTERATIONS OF THE BASEMENT MEMBRANE OF THE DERMAL AND EPIDERMAL LAYERS OF THE HOOF IN HORSES WITH ACUTE LAMINITIS
title_full	HISTOLOGIC ALTERATIONS OF THE BASEMENT MEMBRANE OF THE DERMAL AND EPIDERMAL LAYERS OF THE HOOF IN HORSES WITH ACUTE LAMINITIS
title_fullStr	HISTOLOGIC ALTERATIONS OF THE BASEMENT MEMBRANE OF THE DERMAL AND EPIDERMAL LAYERS OF THE HOOF IN HORSES WITH ACUTE LAMINITIS
title_full_unstemmed	HISTOLOGIC ALTERATIONS OF THE BASEMENT MEMBRANE OF THE DERMAL AND EPIDERMAL LAYERS OF THE HOOF IN HORSES WITH ACUTE LAMINITIS
title_sort	histologic alterations of the basement membrane of the dermal and epidermal layers of the hoof in horses with acute laminitis
publisher	Sociedad Chilena de Anatomía
publishDate	2004
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022004000400012
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HISTOLOGIC ALTERATIONS OF THE BASEMENT MEMBRANE OF THE DERMAL AND EPIDERMAL LAYERS OF THE HOOF IN HORSES WITH ACUTE LAMINITIS

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