Histopathologic Changes of Rat Tracheal Mucosa Following Formaldehyde Exposure

Formaldehyde is a chemical, which is used traditionally for fixing the cadaver. It is vaporized during dissection and practical studying on cadaver. Studies show that this vapor can cause some clinical symptoms such as throat, eye, skin and nasal irritation. This study was designed to determine the...

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Autores principales:	Davarian,Ali, Fazeli,Seyyed Amirhossein, Azarhoush,Ramin, Jafar Golalipour,Mohammad
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2005
Materias:	Formaldehyde exposure Rat Tracheal mucosa
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022005000400013
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spelling	oai:scielo:S0717-950220050004000132006-01-19Histopathologic Changes of Rat Tracheal Mucosa Following Formaldehyde ExposureDavarian,AliFazeli,Seyyed AmirhosseinAzarhoush,RaminJafar Golalipour,Mohammad Formaldehyde exposure Rat Tracheal mucosa Formaldehyde is a chemical, which is used traditionally for fixing the cadaver. It is vaporized during dissection and practical studying on cadaver. Studies show that this vapor can cause some clinical symptoms such as throat, eye, skin and nasal irritation. This study was designed to determine the histopathologic changes of rat tracheal mucosa while all of the experiments were exposed to formaldehyde for 18 weeks. This study was performed on 28, 6-7 weeks postnatal albino Wistar rats. The rats were divided into 3 case groups (E1: 4h/d, 4d/w; E2: 2h/d, 4d/w; E3: 2h/d, 2d/w) and 1 control group. The tracheal specimens were sectioned and stained with H&E technique for histopathologic study. An epithelial disorganization, cilia disappearance, slight dysplastic changes and slight subepithelial lymphocytic infiltration were observed in the case of E1. Epithelial disorganization, irregular cilia and slight subepithelial infiltration were seen in E2 and E3 groups. The results of this study show that "the more exposure to formaldehyde vapor, the more intense epithelial changes"info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.23 n.4 20052005-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022005000400013en10.4067/S0717-95022005000400013
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Formaldehyde exposure Rat Tracheal mucosa
spellingShingle	Formaldehyde exposure Rat Tracheal mucosa Davarian,Ali Fazeli,Seyyed Amirhossein Azarhoush,Ramin Jafar Golalipour,Mohammad Histopathologic Changes of Rat Tracheal Mucosa Following Formaldehyde Exposure
description	Formaldehyde is a chemical, which is used traditionally for fixing the cadaver. It is vaporized during dissection and practical studying on cadaver. Studies show that this vapor can cause some clinical symptoms such as throat, eye, skin and nasal irritation. This study was designed to determine the histopathologic changes of rat tracheal mucosa while all of the experiments were exposed to formaldehyde for 18 weeks. This study was performed on 28, 6-7 weeks postnatal albino Wistar rats. The rats were divided into 3 case groups (E1: 4h/d, 4d/w; E2: 2h/d, 4d/w; E3: 2h/d, 2d/w) and 1 control group. The tracheal specimens were sectioned and stained with H&E technique for histopathologic study. An epithelial disorganization, cilia disappearance, slight dysplastic changes and slight subepithelial lymphocytic infiltration were observed in the case of E1. Epithelial disorganization, irregular cilia and slight subepithelial infiltration were seen in E2 and E3 groups. The results of this study show that "the more exposure to formaldehyde vapor, the more intense epithelial changes"
author	Davarian,Ali Fazeli,Seyyed Amirhossein Azarhoush,Ramin Jafar Golalipour,Mohammad
author_facet	Davarian,Ali Fazeli,Seyyed Amirhossein Azarhoush,Ramin Jafar Golalipour,Mohammad
author_sort	Davarian,Ali
title	Histopathologic Changes of Rat Tracheal Mucosa Following Formaldehyde Exposure
title_short	Histopathologic Changes of Rat Tracheal Mucosa Following Formaldehyde Exposure
title_full	Histopathologic Changes of Rat Tracheal Mucosa Following Formaldehyde Exposure
title_fullStr	Histopathologic Changes of Rat Tracheal Mucosa Following Formaldehyde Exposure
title_full_unstemmed	Histopathologic Changes of Rat Tracheal Mucosa Following Formaldehyde Exposure
title_sort	histopathologic changes of rat tracheal mucosa following formaldehyde exposure
publisher	Sociedad Chilena de Anatomía
publishDate	2005
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022005000400013
work_keys_str_mv	AT davarianali histopathologicchangesofrattrachealmucosafollowingformaldehydeexposure AT fazeliseyyedamirhossein histopathologicchangesofrattrachealmucosafollowingformaldehydeexposure AT azarhoushramin histopathologicchangesofrattrachealmucosafollowingformaldehydeexposure AT jafargolalipourmohammad histopathologicchangesofrattrachealmucosafollowingformaldehydeexposure
_version_	1718444571703115776

Histopathologic Changes of Rat Tracheal Mucosa Following Formaldehyde Exposure

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