Evaluation of the Estral Cycle in Rats after Treatmen twith Dexamethasone for Polycystic Ovaries, Induced by Constant Illumination

The study aimed at obtaining basic information about estrous cycle in rats treated with dexamethasone, for polycystic ovaries, induced by constant illumination. It was used 30 female rats (Rattus norvegicus albinus) from the lineage Wistar, with 90 days years old, divided according the following gro...

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Autores principales: Barros,Heitor Arôxa, Moraes,Eleonora Figueredo de, Maia,Carina Scanoni, Teixeira,Álvaro Aguiar Coelho, Teixeira,ValériaWanderley
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Publicado: Sociedad Chilena de Anatomía 2006
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000400035
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spelling oai:scielo:S0717-950220060004000352007-01-24Evaluation of the Estral Cycle in Rats after Treatmen twith Dexamethasone for Polycystic Ovaries, Induced by Constant IlluminationBarros,Heitor ArôxaMoraes,Eleonora Figueredo deMaia,Carina ScanoniTeixeira,Álvaro Aguiar CoelhoTeixeira,ValériaWanderley Estrous cycle Polycystic ovaries Dexamethasone Rats The study aimed at obtaining basic information about estrous cycle in rats treated with dexamethasone, for polycystic ovaries, induced by constant illumination. It was used 30 female rats (Rattus norvegicus albinus) from the lineage Wistar, with 90 days years old, divided according the following groups: Group I - rats maintained in a light/dark cycle for 12/12 hours, and after 100 days submitted to the cyclicity evaluation (control); Group II - rats maintained under constant illumination during 100 days and after submitted to the cyclicity evaluation; Group III - rats maintained under constant illumination during 100 days and after treated with dexamethasone for five days, and, then, submitted to the cyclicity evaluation. The results showed that after 100 days of experiment, the animals from group I presented a normal cyclicity, being observed the four phases of the cycle. In the animals of groups II and III, it was observed a higher incidence in the estrous phase, with 85% and 76,5% respectively, characterizing the state of permanent estrous. It was observed the phase of diestrous with 15% in group II, and 23,5% in group III, not being observed the phases of proestrous and metaestrous. After treatment with dexamethasone, it was verified a great reduction in the estrous phases in the animals from group III, what was also observed in the animals from group II, reaching numbers of 34,5% and 20,85%, respectively. Yet, there was an increase in the diestrous phase in group II (64,57%), and group III (75%). It has been noticed in these groups the presence of the proestrous phase with 0,92% in group II and 4,15% in group III, not being observed the metaestrous phase. The treatment with dexamethasone during five days produces, more rapidly, a possible retake of the estrous cycle in rats with ovarian polycystic ovariesinfo:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.24 n.3 20062006-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000400035en10.4067/S0717-95022006000400035
institution Scielo Chile
collection Scielo Chile
language English
topic Estrous cycle
Polycystic ovaries
Dexamethasone
Rats
spellingShingle Estrous cycle
Polycystic ovaries
Dexamethasone
Rats
Barros,Heitor Arôxa
Moraes,Eleonora Figueredo de
Maia,Carina Scanoni
Teixeira,Álvaro Aguiar Coelho
Teixeira,ValériaWanderley
Evaluation of the Estral Cycle in Rats after Treatmen twith Dexamethasone for Polycystic Ovaries, Induced by Constant Illumination
description The study aimed at obtaining basic information about estrous cycle in rats treated with dexamethasone, for polycystic ovaries, induced by constant illumination. It was used 30 female rats (Rattus norvegicus albinus) from the lineage Wistar, with 90 days years old, divided according the following groups: Group I - rats maintained in a light/dark cycle for 12/12 hours, and after 100 days submitted to the cyclicity evaluation (control); Group II - rats maintained under constant illumination during 100 days and after submitted to the cyclicity evaluation; Group III - rats maintained under constant illumination during 100 days and after treated with dexamethasone for five days, and, then, submitted to the cyclicity evaluation. The results showed that after 100 days of experiment, the animals from group I presented a normal cyclicity, being observed the four phases of the cycle. In the animals of groups II and III, it was observed a higher incidence in the estrous phase, with 85% and 76,5% respectively, characterizing the state of permanent estrous. It was observed the phase of diestrous with 15% in group II, and 23,5% in group III, not being observed the phases of proestrous and metaestrous. After treatment with dexamethasone, it was verified a great reduction in the estrous phases in the animals from group III, what was also observed in the animals from group II, reaching numbers of 34,5% and 20,85%, respectively. Yet, there was an increase in the diestrous phase in group II (64,57%), and group III (75%). It has been noticed in these groups the presence of the proestrous phase with 0,92% in group II and 4,15% in group III, not being observed the metaestrous phase. The treatment with dexamethasone during five days produces, more rapidly, a possible retake of the estrous cycle in rats with ovarian polycystic ovaries
author Barros,Heitor Arôxa
Moraes,Eleonora Figueredo de
Maia,Carina Scanoni
Teixeira,Álvaro Aguiar Coelho
Teixeira,ValériaWanderley
author_facet Barros,Heitor Arôxa
Moraes,Eleonora Figueredo de
Maia,Carina Scanoni
Teixeira,Álvaro Aguiar Coelho
Teixeira,ValériaWanderley
author_sort Barros,Heitor Arôxa
title Evaluation of the Estral Cycle in Rats after Treatmen twith Dexamethasone for Polycystic Ovaries, Induced by Constant Illumination
title_short Evaluation of the Estral Cycle in Rats after Treatmen twith Dexamethasone for Polycystic Ovaries, Induced by Constant Illumination
title_full Evaluation of the Estral Cycle in Rats after Treatmen twith Dexamethasone for Polycystic Ovaries, Induced by Constant Illumination
title_fullStr Evaluation of the Estral Cycle in Rats after Treatmen twith Dexamethasone for Polycystic Ovaries, Induced by Constant Illumination
title_full_unstemmed Evaluation of the Estral Cycle in Rats after Treatmen twith Dexamethasone for Polycystic Ovaries, Induced by Constant Illumination
title_sort evaluation of the estral cycle in rats after treatmen twith dexamethasone for polycystic ovaries, induced by constant illumination
publisher Sociedad Chilena de Anatomía
publishDate 2006
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000400035
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