Histological Evaluation of the Induced Endometriosis in Rats, after Treatment with Dexamethasone

The present research had the purpose to analyze morphologically the sites of endometrial implants on the external area of the musculature of the anterior abdominal wall of female rats, treated with dexamethasone. For so, these 15 albino female rats were used (Rattus norvegicus albinus), of the linea...

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Autores principales: Batista,Ana Paula Castor, Conceição,Ana Paula Maria da, Moraes,Eleonora de Figueiredo, Teixeira,Álvaro Aguiar Coelho, Wanderley Teixeira,Valéria
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2006
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000500008
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spelling oai:scielo:S0717-950220060005000082007-05-09Histological Evaluation of the Induced Endometriosis in Rats, after Treatment with DexamethasoneBatista,Ana Paula CastorConceição,Ana Paula Maria daMoraes,Eleonora de FigueiredoTeixeira,Álvaro Aguiar CoelhoWanderley Teixeira,Valéria Endometriosis Dexamethasone Steriods Hormones Metaplasia The present research had the purpose to analyze morphologically the sites of endometrial implants on the external area of the musculature of the anterior abdominal wall of female rats, treated with dexamethasone. For so, these 15 albino female rats were used (Rattus norvegicus albinus), of the lineage Wistar with 90 days of age, that were submitted to the induction of the endometriosis, and divided in the following groups: Group I ­ induced female rats to endometriosis and evaluated after 21 days (control); Group II ­ induced female rats to endometriosis and after 21 days, treated with dexamethasone for 10 days; Group III - induced female rats to endometriosis, and after 21 days, treated with dexamethasone for 15 days. The dexamethasone was administered in the dosage of 0,8 mg/day/animal. Our results showed that the chronic inflammatory process in the endometriosis doesn't decrease after treatment with dexamethasone for 10 days, while the treatment with dexamethasone for 15 days reverted the chronic inflammatory process in the endometriosis, besides stimulating the proliferation of glands in endometrial implantsinfo:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.24 n.4 20062006-01-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000500008en10.4067/S0717-95022006000500008
institution Scielo Chile
collection Scielo Chile
language English
topic Endometriosis
Dexamethasone
Steriods
Hormones
Metaplasia
spellingShingle Endometriosis
Dexamethasone
Steriods
Hormones
Metaplasia
Batista,Ana Paula Castor
Conceição,Ana Paula Maria da
Moraes,Eleonora de Figueiredo
Teixeira,Álvaro Aguiar Coelho
Wanderley Teixeira,Valéria
Histological Evaluation of the Induced Endometriosis in Rats, after Treatment with Dexamethasone
description The present research had the purpose to analyze morphologically the sites of endometrial implants on the external area of the musculature of the anterior abdominal wall of female rats, treated with dexamethasone. For so, these 15 albino female rats were used (Rattus norvegicus albinus), of the lineage Wistar with 90 days of age, that were submitted to the induction of the endometriosis, and divided in the following groups: Group I ­ induced female rats to endometriosis and evaluated after 21 days (control); Group II ­ induced female rats to endometriosis and after 21 days, treated with dexamethasone for 10 days; Group III - induced female rats to endometriosis, and after 21 days, treated with dexamethasone for 15 days. The dexamethasone was administered in the dosage of 0,8 mg/day/animal. Our results showed that the chronic inflammatory process in the endometriosis doesn't decrease after treatment with dexamethasone for 10 days, while the treatment with dexamethasone for 15 days reverted the chronic inflammatory process in the endometriosis, besides stimulating the proliferation of glands in endometrial implants
author Batista,Ana Paula Castor
Conceição,Ana Paula Maria da
Moraes,Eleonora de Figueiredo
Teixeira,Álvaro Aguiar Coelho
Wanderley Teixeira,Valéria
author_facet Batista,Ana Paula Castor
Conceição,Ana Paula Maria da
Moraes,Eleonora de Figueiredo
Teixeira,Álvaro Aguiar Coelho
Wanderley Teixeira,Valéria
author_sort Batista,Ana Paula Castor
title Histological Evaluation of the Induced Endometriosis in Rats, after Treatment with Dexamethasone
title_short Histological Evaluation of the Induced Endometriosis in Rats, after Treatment with Dexamethasone
title_full Histological Evaluation of the Induced Endometriosis in Rats, after Treatment with Dexamethasone
title_fullStr Histological Evaluation of the Induced Endometriosis in Rats, after Treatment with Dexamethasone
title_full_unstemmed Histological Evaluation of the Induced Endometriosis in Rats, after Treatment with Dexamethasone
title_sort histological evaluation of the induced endometriosis in rats, after treatment with dexamethasone
publisher Sociedad Chilena de Anatomía
publishDate 2006
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022006000500008
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AT conceicaoanapaulamariada histologicalevaluationoftheinducedendometriosisinratsaftertreatmentwithdexamethasone
AT moraeseleonoradefigueiredo histologicalevaluationoftheinducedendometriosisinratsaftertreatmentwithdexamethasone
AT teixeiraalvaroaguiarcoelho histologicalevaluationoftheinducedendometriosisinratsaftertreatmentwithdexamethasone
AT wanderleyteixeiravaleria histologicalevaluationoftheinducedendometriosisinratsaftertreatmentwithdexamethasone
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