Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles

The purpose of this study was to evaluate the efficacy of monoolein gel as a carrier for rhBMP-2 in the healing bone process of critical bone defects created in Wistar rats mandibles using digitalized radiographic method to analyze this process. In the group 1, the rhBMP-2 was dissolved in aqueous s...

Full description

Saved in:
Bibliographic Details
Main Authors: Issa,Joáo Paulo Mardegan, Nascimento,Cássio do, Sato,Sandra, Barbosa,Rodrigo Edson Santos, Benetti,Emerson Toffanello, Albuquerque Junior,Rubens Ferreira de
Language:English
Published: Sociedad Chilena de Anatomía 2007
Subjects:
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000200018
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The purpose of this study was to evaluate the efficacy of monoolein gel as a carrier for rhBMP-2 in the healing bone process of critical bone defects created in Wistar rats mandibles using digitalized radiographic method to analyze this process. In the group 1, the rhBMP-2 was dissolved in aqueous solution and in the group 2, the rhBMP-2 was combined with monoolein gel as a carrier. The results showed that in both of groups it was found efficient bone repair, with a great optical density in the group that the rhBMP-2 was combined with the monoolein gel, but without statistical difference between them