Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles

The purpose of this study was to evaluate the efficacy of monoolein gel as a carrier for rhBMP-2 in the healing bone process of critical bone defects created in Wistar rats mandibles using digitalized radiographic method to analyze this process. In the group 1, the rhBMP-2 was dissolved in aqueous s...

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Autores principales: Issa,Joáo Paulo Mardegan, Nascimento,Cássio do, Sato,Sandra, Barbosa,Rodrigo Edson Santos, Benetti,Emerson Toffanello, Albuquerque Junior,Rubens Ferreira de
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2007
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000200018
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spelling oai:scielo:S0717-950220070002000182007-08-30Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat MandiblesIssa,Joáo Paulo MardeganNascimento,Cássio doSato,SandraBarbosa,Rodrigo Edson SantosBenetti,Emerson ToffanelloAlbuquerque Junior,Rubens Ferreira de Optical densitometry rhBMP-2 Monoolein Bone defects The purpose of this study was to evaluate the efficacy of monoolein gel as a carrier for rhBMP-2 in the healing bone process of critical bone defects created in Wistar rats mandibles using digitalized radiographic method to analyze this process. In the group 1, the rhBMP-2 was dissolved in aqueous solution and in the group 2, the rhBMP-2 was combined with monoolein gel as a carrier. The results showed that in both of groups it was found efficient bone repair, with a great optical density in the group that the rhBMP-2 was combined with the monoolein gel, but without statistical difference between theminfo:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.25 n.2 20072007-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000200018en10.4067/S0717-95022007000200018
institution Scielo Chile
collection Scielo Chile
language English
topic Optical densitometry
rhBMP-2
Monoolein
Bone defects
spellingShingle Optical densitometry
rhBMP-2
Monoolein
Bone defects
Issa,Joáo Paulo Mardegan
Nascimento,Cássio do
Sato,Sandra
Barbosa,Rodrigo Edson Santos
Benetti,Emerson Toffanello
Albuquerque Junior,Rubens Ferreira de
Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles
description The purpose of this study was to evaluate the efficacy of monoolein gel as a carrier for rhBMP-2 in the healing bone process of critical bone defects created in Wistar rats mandibles using digitalized radiographic method to analyze this process. In the group 1, the rhBMP-2 was dissolved in aqueous solution and in the group 2, the rhBMP-2 was combined with monoolein gel as a carrier. The results showed that in both of groups it was found efficient bone repair, with a great optical density in the group that the rhBMP-2 was combined with the monoolein gel, but without statistical difference between them
author Issa,Joáo Paulo Mardegan
Nascimento,Cássio do
Sato,Sandra
Barbosa,Rodrigo Edson Santos
Benetti,Emerson Toffanello
Albuquerque Junior,Rubens Ferreira de
author_facet Issa,Joáo Paulo Mardegan
Nascimento,Cássio do
Sato,Sandra
Barbosa,Rodrigo Edson Santos
Benetti,Emerson Toffanello
Albuquerque Junior,Rubens Ferreira de
author_sort Issa,Joáo Paulo Mardegan
title Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles
title_short Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles
title_full Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles
title_fullStr Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles
title_full_unstemmed Optical Densitometry Study of the Newly Formed Bone Using rhBMP-2 in Wistar Rat Mandibles
title_sort optical densitometry study of the newly formed bone using rhbmp-2 in wistar rat mandibles
publisher Sociedad Chilena de Anatomía
publishDate 2007
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000200018
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