Biochemical Analysis by Calcium Determination on the Newly Formed Bone in Critical Bone Defects Submitted to Different Treatments: A Pilot Study

The aim of this study was to evaluate the calcium dosage of the newly formed bone, in critical bone defects created on the calvarial tissue and filled by different substances, in male Wistar rats. A cylindrical critical bone defect (6x2mm) was created in the posterior portion, left side, on the calv...

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Autores principales: Issa,Joao Paulo Mardegan, Petenusci,Sergio Olavo, Siéssere,Selma, Regalo,Simone Cecilio Hallak, Lopes,Ruberval Armando, Di Matteo,Miguel Ángel Sala, Iyomasa,Mamie Mizusaki, Defino,Helton Luiz Aparecido
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2007
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000300006
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spelling oai:scielo:S0717-950220070003000062007-10-30Biochemical Analysis by Calcium Determination on the Newly Formed Bone in Critical Bone Defects Submitted to Different Treatments: A Pilot StudyIssa,Joao Paulo MardeganPetenusci,Sergio OlavoSiéssere,SelmaRegalo,Simone Cecilio HallakLopes,Ruberval ArmandoDi Matteo,Miguel Ángel SalaIyomasa,Mamie MizusakiDefino,Helton Luiz Aparecido Bone repair Biomaterials rhBMP-2 Carriers Calcium The aim of this study was to evaluate the calcium dosage of the newly formed bone, in critical bone defects created on the calvarial tissue and filled by different substances, in male Wistar rats. A cylindrical critical bone defect (6x2mm) was created in the posterior portion, left side, on the calvarial bone in nine animals and filled with: animals' coagulum, monoolein gel, poloxamer gel, monoolein gel + 1µg rhBMP-2, monoolein gel + 3µg rhBMP-2, monoolein gel + 7µg rhBMP-2, poloxamer gel + 1µg rhBMP-2, poloxamer gel + 3µg rhBMP-2, poloxamer gel + 7µg rhBMP-2. The results of this study showed a positive correlation between the calcium dosage analysis and the newly formed boneinfo:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.25 n.3 20072007-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000300006en10.4067/S0717-95022007000300006
institution Scielo Chile
collection Scielo Chile
language English
topic Bone repair
Biomaterials
rhBMP-2
Carriers
Calcium
spellingShingle Bone repair
Biomaterials
rhBMP-2
Carriers
Calcium
Issa,Joao Paulo Mardegan
Petenusci,Sergio Olavo
Siéssere,Selma
Regalo,Simone Cecilio Hallak
Lopes,Ruberval Armando
Di Matteo,Miguel Ángel Sala
Iyomasa,Mamie Mizusaki
Defino,Helton Luiz Aparecido
Biochemical Analysis by Calcium Determination on the Newly Formed Bone in Critical Bone Defects Submitted to Different Treatments: A Pilot Study
description The aim of this study was to evaluate the calcium dosage of the newly formed bone, in critical bone defects created on the calvarial tissue and filled by different substances, in male Wistar rats. A cylindrical critical bone defect (6x2mm) was created in the posterior portion, left side, on the calvarial bone in nine animals and filled with: animals' coagulum, monoolein gel, poloxamer gel, monoolein gel + 1µg rhBMP-2, monoolein gel + 3µg rhBMP-2, monoolein gel + 7µg rhBMP-2, poloxamer gel + 1µg rhBMP-2, poloxamer gel + 3µg rhBMP-2, poloxamer gel + 7µg rhBMP-2. The results of this study showed a positive correlation between the calcium dosage analysis and the newly formed bone
author Issa,Joao Paulo Mardegan
Petenusci,Sergio Olavo
Siéssere,Selma
Regalo,Simone Cecilio Hallak
Lopes,Ruberval Armando
Di Matteo,Miguel Ángel Sala
Iyomasa,Mamie Mizusaki
Defino,Helton Luiz Aparecido
author_facet Issa,Joao Paulo Mardegan
Petenusci,Sergio Olavo
Siéssere,Selma
Regalo,Simone Cecilio Hallak
Lopes,Ruberval Armando
Di Matteo,Miguel Ángel Sala
Iyomasa,Mamie Mizusaki
Defino,Helton Luiz Aparecido
author_sort Issa,Joao Paulo Mardegan
title Biochemical Analysis by Calcium Determination on the Newly Formed Bone in Critical Bone Defects Submitted to Different Treatments: A Pilot Study
title_short Biochemical Analysis by Calcium Determination on the Newly Formed Bone in Critical Bone Defects Submitted to Different Treatments: A Pilot Study
title_full Biochemical Analysis by Calcium Determination on the Newly Formed Bone in Critical Bone Defects Submitted to Different Treatments: A Pilot Study
title_fullStr Biochemical Analysis by Calcium Determination on the Newly Formed Bone in Critical Bone Defects Submitted to Different Treatments: A Pilot Study
title_full_unstemmed Biochemical Analysis by Calcium Determination on the Newly Formed Bone in Critical Bone Defects Submitted to Different Treatments: A Pilot Study
title_sort biochemical analysis by calcium determination on the newly formed bone in critical bone defects submitted to different treatments: a pilot study
publisher Sociedad Chilena de Anatomía
publishDate 2007
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000300006
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