Benign Inclusions in Lymph Nodes

Benign inclusions are foci of non-neoplastic ectopic tissue in lymph nodes. They are classified into three types: epithelial, nevomelanocytic and decidual. It is important to identify them for the differential diagnosis with lymph node metastases, particularly among patients who present proliferativ...

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Autores principales:	Spinardi,Julia Regazzini, Goncalves,Isis Rocha Dias, La Falce,Thiago Souza, Fregnani,José Humberto Tavares Guerreiro, Barros,Mirna Duarte, Macea,José Rafael
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2007
Materias:	Ectopic tissues Lymph node Melanocyte Paramesonephricus ducts Thyroid gland Breast
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000300026
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spelling	oai:scielo:S0717-950220070003000262007-10-30Benign Inclusions in Lymph NodesSpinardi,Julia RegazziniGoncalves,Isis Rocha DiasLa Falce,Thiago SouzaFregnani,José Humberto Tavares GuerreiroBarros,Mirna DuarteMacea,José Rafael Ectopic tissues Lymph node Melanocyte Paramesonephricus ducts Thyroid gland Breast Benign inclusions are foci of non-neoplastic ectopic tissue in lymph nodes. They are classified into three types: epithelial, nevomelanocytic and decidual. It is important to identify them for the differential diagnosis with lymph node metastases, particularly among patients who present proliferative benign lesions. In general, epithelial inclusions are presented inside lymph nodes as epithelial cysts or as numerous structures resembling ducts. The cells of these structures may originate from the cells of paramesonephricus ducts, salivary glands, breast tissue, thyroid follicles, squamous epithelium or mesothelium. Paramesonephricus -type inclusions are almost exclusively found in pelvic lymph nodes and, in appearance, they resemble the epithelium of the uterine tube. Inclusions of breast tissue are composed predominantly of ectopic mammary glands and ducts that present diverse morphological characteristics that still have obscure etiology. Thyroid-type inclusions are frequently found in cervical and axillary lymph nodes, and it is believed that, embryologically, they arise from the mixing of tissues from which lymph nodes and the thyroid gland originate. Mesothelial inclusions occur preferentially in the mediastinal lymph nodes of patients who are affected by pleural or pericardial effusions. Aggregates of melanocytic cells are generally found in the lymph node capsule. The explanation for this occurrence is uncertain, but it is believed to be a consequence of incorrect migration of neural crest cells, or because of "benign metastases" of nevi present in the skin. Studies on benign inclusions in lymph nodes take on importance through assisting in correctly diagnosing the presence of metastasesinfo:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.25 n.3 20072007-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000300026en10.4067/S0717-95022007000300026
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Ectopic tissues Lymph node Melanocyte Paramesonephricus ducts Thyroid gland Breast
spellingShingle	Ectopic tissues Lymph node Melanocyte Paramesonephricus ducts Thyroid gland Breast Spinardi,Julia Regazzini Goncalves,Isis Rocha Dias La Falce,Thiago Souza Fregnani,José Humberto Tavares Guerreiro Barros,Mirna Duarte Macea,José Rafael Benign Inclusions in Lymph Nodes
description	Benign inclusions are foci of non-neoplastic ectopic tissue in lymph nodes. They are classified into three types: epithelial, nevomelanocytic and decidual. It is important to identify them for the differential diagnosis with lymph node metastases, particularly among patients who present proliferative benign lesions. In general, epithelial inclusions are presented inside lymph nodes as epithelial cysts or as numerous structures resembling ducts. The cells of these structures may originate from the cells of paramesonephricus ducts, salivary glands, breast tissue, thyroid follicles, squamous epithelium or mesothelium. Paramesonephricus -type inclusions are almost exclusively found in pelvic lymph nodes and, in appearance, they resemble the epithelium of the uterine tube. Inclusions of breast tissue are composed predominantly of ectopic mammary glands and ducts that present diverse morphological characteristics that still have obscure etiology. Thyroid-type inclusions are frequently found in cervical and axillary lymph nodes, and it is believed that, embryologically, they arise from the mixing of tissues from which lymph nodes and the thyroid gland originate. Mesothelial inclusions occur preferentially in the mediastinal lymph nodes of patients who are affected by pleural or pericardial effusions. Aggregates of melanocytic cells are generally found in the lymph node capsule. The explanation for this occurrence is uncertain, but it is believed to be a consequence of incorrect migration of neural crest cells, or because of "benign metastases" of nevi present in the skin. Studies on benign inclusions in lymph nodes take on importance through assisting in correctly diagnosing the presence of metastases
author	Spinardi,Julia Regazzini Goncalves,Isis Rocha Dias La Falce,Thiago Souza Fregnani,José Humberto Tavares Guerreiro Barros,Mirna Duarte Macea,José Rafael
author_facet	Spinardi,Julia Regazzini Goncalves,Isis Rocha Dias La Falce,Thiago Souza Fregnani,José Humberto Tavares Guerreiro Barros,Mirna Duarte Macea,José Rafael
author_sort	Spinardi,Julia Regazzini
title	Benign Inclusions in Lymph Nodes
title_short	Benign Inclusions in Lymph Nodes
title_full	Benign Inclusions in Lymph Nodes
title_fullStr	Benign Inclusions in Lymph Nodes
title_full_unstemmed	Benign Inclusions in Lymph Nodes
title_sort	benign inclusions in lymph nodes
publisher	Sociedad Chilena de Anatomía
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000300026
work_keys_str_mv	AT spinardijuliaregazzini benigninclusionsinlymphnodes AT goncalvesisisrochadias benigninclusionsinlymphnodes AT lafalcethiagosouza benigninclusionsinlymphnodes AT fregnanijosehumbertotavaresguerreiro benigninclusionsinlymphnodes AT barrosmirnaduarte benigninclusionsinlymphnodes AT maceajoserafael benigninclusionsinlymphnodes
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Benign Inclusions in Lymph Nodes

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