Histopathological and Histometrical Assessment of Boron Exposure Effects on Mouse Spermatogenesis

Boron is a chemical element widely used in many industrial activities. Exposure to it affects many organs in mammals, mainly reproductive male organs. This work evaluates boron effect in testis. For this purpose, 12mg Boron/L of drinking water, equivalent to Arica tap water, was given for 42 days to...

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Autores principales:	Bustos-Obregon,E, Carvallo,M, Hartley-Belmar,R, Sarabia,L, Ponce,C
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2007
Materias:	Boron Testicular histopathology Morphometry Mouse spermatogenesis
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000400039
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spelling	oai:scielo:S0717-950220070004000392008-04-15Histopathological and Histometrical Assessment of Boron Exposure Effects on Mouse SpermatogenesisBustos-Obregon,ECarvallo,MHartley-Belmar,RSarabia,LPonce,C Boron Testicular histopathology Morphometry Mouse spermatogenesis Boron is a chemical element widely used in many industrial activities. Exposure to it affects many organs in mammals, mainly reproductive male organs. This work evaluates boron effect in testis. For this purpose, 12mg Boron/L of drinking water, equivalent to Arica tap water, was given for 42 days to 85 days old CFl male mice (experimental group). Another group (control group) drunk tap water of Santiago (0.6mg Boron/L) was used. Testicular histopathology and morphometric analysis was done. These studies showed that Borum induces alterations such as epithelial vacuolization, blockage of the tubular lumen and atrophy. Morphometrical data showed that Borom induces also enlargement of tubular diameter, epithelial height and tubular lumen. Therefore, it is concluded that Boron acts as testicular toxicant and that further studies are needed to establish its mechanism of action upon spermatogenesisinfo:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.25 n.4 20072007-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000400039en10.4067/S0717-95022007000400039
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Boron Testicular histopathology Morphometry Mouse spermatogenesis
spellingShingle	Boron Testicular histopathology Morphometry Mouse spermatogenesis Bustos-Obregon,E Carvallo,M Hartley-Belmar,R Sarabia,L Ponce,C Histopathological and Histometrical Assessment of Boron Exposure Effects on Mouse Spermatogenesis
description	Boron is a chemical element widely used in many industrial activities. Exposure to it affects many organs in mammals, mainly reproductive male organs. This work evaluates boron effect in testis. For this purpose, 12mg Boron/L of drinking water, equivalent to Arica tap water, was given for 42 days to 85 days old CFl male mice (experimental group). Another group (control group) drunk tap water of Santiago (0.6mg Boron/L) was used. Testicular histopathology and morphometric analysis was done. These studies showed that Borum induces alterations such as epithelial vacuolization, blockage of the tubular lumen and atrophy. Morphometrical data showed that Borom induces also enlargement of tubular diameter, epithelial height and tubular lumen. Therefore, it is concluded that Boron acts as testicular toxicant and that further studies are needed to establish its mechanism of action upon spermatogenesis
author	Bustos-Obregon,E Carvallo,M Hartley-Belmar,R Sarabia,L Ponce,C
author_facet	Bustos-Obregon,E Carvallo,M Hartley-Belmar,R Sarabia,L Ponce,C
author_sort	Bustos-Obregon,E
title	Histopathological and Histometrical Assessment of Boron Exposure Effects on Mouse Spermatogenesis
title_short	Histopathological and Histometrical Assessment of Boron Exposure Effects on Mouse Spermatogenesis
title_full	Histopathological and Histometrical Assessment of Boron Exposure Effects on Mouse Spermatogenesis
title_fullStr	Histopathological and Histometrical Assessment of Boron Exposure Effects on Mouse Spermatogenesis
title_full_unstemmed	Histopathological and Histometrical Assessment of Boron Exposure Effects on Mouse Spermatogenesis
title_sort	histopathological and histometrical assessment of boron exposure effects on mouse spermatogenesis
publisher	Sociedad Chilena de Anatomía
publishDate	2007
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022007000400039
work_keys_str_mv	AT bustosobregone histopathologicalandhistometricalassessmentofboronexposureeffectsonmousespermatogenesis AT carvallom histopathologicalandhistometricalassessmentofboronexposureeffectsonmousespermatogenesis AT hartleybelmarr histopathologicalandhistometricalassessmentofboronexposureeffectsonmousespermatogenesis AT sarabial histopathologicalandhistometricalassessmentofboronexposureeffectsonmousespermatogenesis AT poncec histopathologicalandhistometricalassessmentofboronexposureeffectsonmousespermatogenesis
_version_	1718444617220751360

Histopathological and Histometrical Assessment of Boron Exposure Effects on Mouse Spermatogenesis

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