Effect of the Treatment with Dexamethasone, for 10 and 15 Days, on the Fertility in Induced Rats to Polycystic Ovaries, by Constant Illumination

The present study had the objective of obtaining information about fertility in rats treated with dexamethasone for 10 and 15 days consecutively, to polycystic ovaries, induced by constant illumination. It was used 40 albino rats (Rattus norvegicus albinus), aged 90 days, form the lineage Wistar, wh...

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Autores principales:	Moraes,Eleonora de Figueiredo, Wanderley Teixeira,Valéria, Teixeira,Álvaro Aguiar Coelho, Silva,Welma Emídio da, Batista,Ana Paula Castor, Lemos,Ana Janaína Jeanine Martins de
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2008
Materias:	Fertility Polycystic ovaries Dexamethasone Rats
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000300024
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spelling	oai:scielo:S0717-950220080003000242009-03-13Effect of the Treatment with Dexamethasone, for 10 and 15 Days, on the Fertility in Induced Rats to Polycystic Ovaries, by Constant IlluminationMoraes,Eleonora de FigueiredoWanderley Teixeira,ValériaTeixeira,Álvaro Aguiar CoelhoSilva,Welma Emídio daBatista,Ana Paula CastorLemos,Ana Janaína Jeanine Martins de Fertility Polycystic ovaries Dexamethasone Rats The present study had the objective of obtaining information about fertility in rats treated with dexamethasone for 10 and 15 days consecutively, to polycystic ovaries, induced by constant illumination. It was used 40 albino rats (Rattus norvegicus albinus), aged 90 days, form the lineage Wistar, which were split, randomly, in four groups, each constituted of 10 animals, namely: Group I - rats kept in a clear/dark cycle for 12/12 hours, and after 100 days submitted to fertility evaluation (control); Group II - rats kept under constant illumination during 100 days and then submitted to fertility evaluation; Group III - rats kept under constant illumination during 100 days, then treated with dexamethasone for 10 days and submitted to fertility evaluation; Group IV - rats kept under constant illumination during 100 days, then treated with dexamethasone for 15 days and submitted to fertility evaluation. The results showed that the number of implanted sites was 38(G1), 37(G2), 32(G3) and 06(G4). The reduction in group IV was due to the high mortality during the experiment, probably because of the prolonged treatment with dexamethasone. These sites presented similar histological aspects. The macroscopic analysis of the neonates haven't shown any indication of malformation. Also, abortion haven't been observed. The treatment with dexamethasone for 10 days in rats does not affect the fertility and the development of the lungs, liver and kidneys of neonates, while the administration during 15 days leads to a high maternal mortality.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.26 n.3 20082008-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000300024en10.4067/S0717-95022008000300024
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Fertility Polycystic ovaries Dexamethasone Rats
spellingShingle	Fertility Polycystic ovaries Dexamethasone Rats Moraes,Eleonora de Figueiredo Wanderley Teixeira,Valéria Teixeira,Álvaro Aguiar Coelho Silva,Welma Emídio da Batista,Ana Paula Castor Lemos,Ana Janaína Jeanine Martins de Effect of the Treatment with Dexamethasone, for 10 and 15 Days, on the Fertility in Induced Rats to Polycystic Ovaries, by Constant Illumination
description	The present study had the objective of obtaining information about fertility in rats treated with dexamethasone for 10 and 15 days consecutively, to polycystic ovaries, induced by constant illumination. It was used 40 albino rats (Rattus norvegicus albinus), aged 90 days, form the lineage Wistar, which were split, randomly, in four groups, each constituted of 10 animals, namely: Group I - rats kept in a clear/dark cycle for 12/12 hours, and after 100 days submitted to fertility evaluation (control); Group II - rats kept under constant illumination during 100 days and then submitted to fertility evaluation; Group III - rats kept under constant illumination during 100 days, then treated with dexamethasone for 10 days and submitted to fertility evaluation; Group IV - rats kept under constant illumination during 100 days, then treated with dexamethasone for 15 days and submitted to fertility evaluation. The results showed that the number of implanted sites was 38(G1), 37(G2), 32(G3) and 06(G4). The reduction in group IV was due to the high mortality during the experiment, probably because of the prolonged treatment with dexamethasone. These sites presented similar histological aspects. The macroscopic analysis of the neonates haven't shown any indication of malformation. Also, abortion haven't been observed. The treatment with dexamethasone for 10 days in rats does not affect the fertility and the development of the lungs, liver and kidneys of neonates, while the administration during 15 days leads to a high maternal mortality.
author	Moraes,Eleonora de Figueiredo Wanderley Teixeira,Valéria Teixeira,Álvaro Aguiar Coelho Silva,Welma Emídio da Batista,Ana Paula Castor Lemos,Ana Janaína Jeanine Martins de
author_facet	Moraes,Eleonora de Figueiredo Wanderley Teixeira,Valéria Teixeira,Álvaro Aguiar Coelho Silva,Welma Emídio da Batista,Ana Paula Castor Lemos,Ana Janaína Jeanine Martins de
author_sort	Moraes,Eleonora de Figueiredo
title	Effect of the Treatment with Dexamethasone, for 10 and 15 Days, on the Fertility in Induced Rats to Polycystic Ovaries, by Constant Illumination
title_short	Effect of the Treatment with Dexamethasone, for 10 and 15 Days, on the Fertility in Induced Rats to Polycystic Ovaries, by Constant Illumination
title_full	Effect of the Treatment with Dexamethasone, for 10 and 15 Days, on the Fertility in Induced Rats to Polycystic Ovaries, by Constant Illumination
title_fullStr	Effect of the Treatment with Dexamethasone, for 10 and 15 Days, on the Fertility in Induced Rats to Polycystic Ovaries, by Constant Illumination
title_full_unstemmed	Effect of the Treatment with Dexamethasone, for 10 and 15 Days, on the Fertility in Induced Rats to Polycystic Ovaries, by Constant Illumination
title_sort	effect of the treatment with dexamethasone, for 10 and 15 days, on the fertility in induced rats to polycystic ovaries, by constant illumination
publisher	Sociedad Chilena de Anatomía
publishDate	2008
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000300024
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Effect of the Treatment with Dexamethasone, for 10 and 15 Days, on the Fertility in Induced Rats to Polycystic Ovaries, by Constant Illumination

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