Intraoral Mucoepidermoid Carcinoma of Salivary Glands: Lack of Association Among Clinicopathological Features and Immunoexpression of c-erbB-2 in 29 Cases

The association among clinicopathological features and c-erbB-2 oncoprotein expression was evaluated in twenty-nine cases of intra-oral mucoepidermoid carcinoma (MEC). MEC was prevalent in the female gender (79.3%), tumors were more frequent in ages between 21 and 40 years (48.3%), and the palate wa...

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Autores principales:	Bernardes,Vanessa Fátima, Ramos-Jorge,Maria Letícia, Vieira Carmo,Maria Auxiliadora, Cardoso,Sérgio Vitorino, Alves Mesquita,Ricardo, Ferreira Aguiar,Maria Cássia
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2008
Materias:	c-erbB-2 Her-2/neu Immunohistochemistry Mucoepidermoid carcinoma Salivary gland neoplasms
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000400036
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spelling	oai:scielo:S0717-950220080004000362009-05-25Intraoral Mucoepidermoid Carcinoma of Salivary Glands: Lack of Association Among Clinicopathological Features and Immunoexpression of c-erbB-2 in 29 CasesBernardes,Vanessa FátimaRamos-Jorge,Maria LetíciaVieira Carmo,Maria AuxiliadoraCardoso,Sérgio VitorinoAlves Mesquita,RicardoFerreira Aguiar,Maria Cássia c-erbB-2 Her-2/neu Immunohistochemistry Mucoepidermoid carcinoma Salivary gland neoplasms The association among clinicopathological features and c-erbB-2 oncoprotein expression was evaluated in twenty-nine cases of intra-oral mucoepidermoid carcinoma (MEC). MEC was prevalent in the female gender (79.3%), tumors were more frequent in ages between 21 and 40 years (48.3%), and the palate was the most commonly affected site (72.4%). Microscopically, 27 cases (93.1%) were classified as low grade of malignancy. The c-erbB-2 expression was considered positive in 9 (31%) cases and no significant association (p>0.05) was found among protein expression and gender ñor between patient age and site or histological grade of the lesión. c-erbB-2 expression in MEC may reflect intrisinc biologic properties of salivary gland neoplasms and may be linked to histogenesis and cellular differentiaton.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.26 n.4 20082008-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000400036en10.4067/S0717-95022008000400036
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	c-erbB-2 Her-2/neu Immunohistochemistry Mucoepidermoid carcinoma Salivary gland neoplasms
spellingShingle	c-erbB-2 Her-2/neu Immunohistochemistry Mucoepidermoid carcinoma Salivary gland neoplasms Bernardes,Vanessa Fátima Ramos-Jorge,Maria Letícia Vieira Carmo,Maria Auxiliadora Cardoso,Sérgio Vitorino Alves Mesquita,Ricardo Ferreira Aguiar,Maria Cássia Intraoral Mucoepidermoid Carcinoma of Salivary Glands: Lack of Association Among Clinicopathological Features and Immunoexpression of c-erbB-2 in 29 Cases
description	The association among clinicopathological features and c-erbB-2 oncoprotein expression was evaluated in twenty-nine cases of intra-oral mucoepidermoid carcinoma (MEC). MEC was prevalent in the female gender (79.3%), tumors were more frequent in ages between 21 and 40 years (48.3%), and the palate was the most commonly affected site (72.4%). Microscopically, 27 cases (93.1%) were classified as low grade of malignancy. The c-erbB-2 expression was considered positive in 9 (31%) cases and no significant association (p>0.05) was found among protein expression and gender ñor between patient age and site or histological grade of the lesión. c-erbB-2 expression in MEC may reflect intrisinc biologic properties of salivary gland neoplasms and may be linked to histogenesis and cellular differentiaton.
author	Bernardes,Vanessa Fátima Ramos-Jorge,Maria Letícia Vieira Carmo,Maria Auxiliadora Cardoso,Sérgio Vitorino Alves Mesquita,Ricardo Ferreira Aguiar,Maria Cássia
author_facet	Bernardes,Vanessa Fátima Ramos-Jorge,Maria Letícia Vieira Carmo,Maria Auxiliadora Cardoso,Sérgio Vitorino Alves Mesquita,Ricardo Ferreira Aguiar,Maria Cássia
author_sort	Bernardes,Vanessa Fátima
title	Intraoral Mucoepidermoid Carcinoma of Salivary Glands: Lack of Association Among Clinicopathological Features and Immunoexpression of c-erbB-2 in 29 Cases
title_short	Intraoral Mucoepidermoid Carcinoma of Salivary Glands: Lack of Association Among Clinicopathological Features and Immunoexpression of c-erbB-2 in 29 Cases
title_full	Intraoral Mucoepidermoid Carcinoma of Salivary Glands: Lack of Association Among Clinicopathological Features and Immunoexpression of c-erbB-2 in 29 Cases
title_fullStr	Intraoral Mucoepidermoid Carcinoma of Salivary Glands: Lack of Association Among Clinicopathological Features and Immunoexpression of c-erbB-2 in 29 Cases
title_full_unstemmed	Intraoral Mucoepidermoid Carcinoma of Salivary Glands: Lack of Association Among Clinicopathological Features and Immunoexpression of c-erbB-2 in 29 Cases
title_sort	intraoral mucoepidermoid carcinoma of salivary glands: lack of association among clinicopathological features and immunoexpression of c-erbb-2 in 29 cases
publisher	Sociedad Chilena de Anatomía
publishDate	2008
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022008000400036
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Intraoral Mucoepidermoid Carcinoma of Salivary Glands: Lack of Association Among Clinicopathological Features and Immunoexpression of c-erbB-2 in 29 Cases

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