Analysis of Myenteric Neurons of the Cecum of Diabetic Rats After Supplementation with Ascorbic Acid

The objective of this work was to investigate the neuroprotective action of the ascorbic acid over the myenteric neurons in the cecum of Wistar rats, four months after induction of the diabetes mellitus experimental with streptozotocin. Three groups with five rats each were used: C- controls, D- dia...

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Autores principales:	Zanoni,Jacqueline Nelisis, Pereira,Priscila Goncalves Cardoso, dos Santos Pereira,Marli Aparecida
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2009
Materias:	Ascorbic acid Diabetes mellitus Oxidative stress Cecum Streptozotocin
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000200013
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spelling	oai:scielo:S0717-950220090002000132009-09-10Analysis of Myenteric Neurons of the Cecum of Diabetic Rats After Supplementation with Ascorbic AcidZanoni,Jacqueline NelisisPereira,Priscila Goncalves Cardosodos Santos Pereira,Marli Aparecida Ascorbic acid Diabetes mellitus Oxidative stress Cecum Streptozotocin The objective of this work was to investigate the neuroprotective action of the ascorbic acid over the myenteric neurons in the cecum of Wistar rats, four months after induction of the diabetes mellitus experimental with streptozotocin. Three groups with five rats each were used: C- controls, D- diabetic, DA- diabetic treated with ascorbic acid. For evidentiation of the myenteric neurons was carried out to Giemsa's technique. Were evaluated the areas of cell bodies of 500 neurons in each group studied. The quantitative analysis was carried out in an area of 16.6 mm2 in each cecum studied. In the animals diabetic observed elevation of the glycemia and glycated hemoglobin. The supplementation with ascorbic acid was effective under the myenteric neurons of the cecum of diabetics rays, since was presented the effect neuroprotective and neurotrofic.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.27 n.2 20092009-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000200013en10.4067/S0717-95022009000200013
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Ascorbic acid Diabetes mellitus Oxidative stress Cecum Streptozotocin
spellingShingle	Ascorbic acid Diabetes mellitus Oxidative stress Cecum Streptozotocin Zanoni,Jacqueline Nelisis Pereira,Priscila Goncalves Cardoso dos Santos Pereira,Marli Aparecida Analysis of Myenteric Neurons of the Cecum of Diabetic Rats After Supplementation with Ascorbic Acid
description	The objective of this work was to investigate the neuroprotective action of the ascorbic acid over the myenteric neurons in the cecum of Wistar rats, four months after induction of the diabetes mellitus experimental with streptozotocin. Three groups with five rats each were used: C- controls, D- diabetic, DA- diabetic treated with ascorbic acid. For evidentiation of the myenteric neurons was carried out to Giemsa's technique. Were evaluated the areas of cell bodies of 500 neurons in each group studied. The quantitative analysis was carried out in an area of 16.6 mm2 in each cecum studied. In the animals diabetic observed elevation of the glycemia and glycated hemoglobin. The supplementation with ascorbic acid was effective under the myenteric neurons of the cecum of diabetics rays, since was presented the effect neuroprotective and neurotrofic.
author	Zanoni,Jacqueline Nelisis Pereira,Priscila Goncalves Cardoso dos Santos Pereira,Marli Aparecida
author_facet	Zanoni,Jacqueline Nelisis Pereira,Priscila Goncalves Cardoso dos Santos Pereira,Marli Aparecida
author_sort	Zanoni,Jacqueline Nelisis
title	Analysis of Myenteric Neurons of the Cecum of Diabetic Rats After Supplementation with Ascorbic Acid
title_short	Analysis of Myenteric Neurons of the Cecum of Diabetic Rats After Supplementation with Ascorbic Acid
title_full	Analysis of Myenteric Neurons of the Cecum of Diabetic Rats After Supplementation with Ascorbic Acid
title_fullStr	Analysis of Myenteric Neurons of the Cecum of Diabetic Rats After Supplementation with Ascorbic Acid
title_full_unstemmed	Analysis of Myenteric Neurons of the Cecum of Diabetic Rats After Supplementation with Ascorbic Acid
title_sort	analysis of myenteric neurons of the cecum of diabetic rats after supplementation with ascorbic acid
publisher	Sociedad Chilena de Anatomía
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000200013
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Analysis of Myenteric Neurons of the Cecum of Diabetic Rats After Supplementation with Ascorbic Acid

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