The Effects of Ovariectomy and Naproxen Treatment on the Strength of Femoral Midshaft and Molar Alveolar Region in Rats

The goal of the present study was to investigate the effects of ovariectomy and naproxen treatment on both femoral and mandibular bone mass and biomechanical competence. Sprague-Dawley rats were used and divided into five groups: baseline, sham ovariectomized, ovariectomized, sham ovariectomized + n...

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Autores principales: Turkozan,N. Y, Ulusoy,A. T, Balcioglu,H. A, Bal,F, Ozel,S
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2009
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300007
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spelling oai:scielo:S0717-950220090003000072010-04-05The Effects of Ovariectomy and Naproxen Treatment on the Strength of Femoral Midshaft and Molar Alveolar Region in RatsTurkozan,N. YUlusoy,A. TBalcioglu,H. ABal,FOzel,S Ovariectomy Naproxen Bone mineral density Maximum load The goal of the present study was to investigate the effects of ovariectomy and naproxen treatment on both femoral and mandibular bone mass and biomechanical competence. Sprague-Dawley rats were used and divided into five groups: baseline, sham ovariectomized, ovariectomized, sham ovariectomized + naproxen treatment, ovariectomized + naproxen treatment. Mandibles and femurs of the rats were extracted and bone mineral density of the extracted specimens were determined. The volumes and ash weights of the femurs and mandibles were estimated. Maximum loads of the femurs and mandibles were determined by using a three point bending test. Ovariectomy decreased bone mineral density of the femoral midshaft, however naproxen prevented this decrease. Neither ovariectomy nor naproxen treatment affected the BMD in the molar alveolar region. Maximum load was found significantly decreased in the femoral midshaft, however, naproxen treatment prevented this decrease. Maximum load of the molar alveolar region did not significantly change. Naproxen prevents the strength characteristics of femoral midshaft afforded by ovariectomy. However, neither ovariectomy nor naproxen has an effect on the molar alveolar region of the mandible.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.27 n.3 20092009-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300007en10.4067/S0717-95022009000300007
institution Scielo Chile
collection Scielo Chile
language English
topic Ovariectomy
Naproxen
Bone mineral density
Maximum load
spellingShingle Ovariectomy
Naproxen
Bone mineral density
Maximum load
Turkozan,N. Y
Ulusoy,A. T
Balcioglu,H. A
Bal,F
Ozel,S
The Effects of Ovariectomy and Naproxen Treatment on the Strength of Femoral Midshaft and Molar Alveolar Region in Rats
description The goal of the present study was to investigate the effects of ovariectomy and naproxen treatment on both femoral and mandibular bone mass and biomechanical competence. Sprague-Dawley rats were used and divided into five groups: baseline, sham ovariectomized, ovariectomized, sham ovariectomized + naproxen treatment, ovariectomized + naproxen treatment. Mandibles and femurs of the rats were extracted and bone mineral density of the extracted specimens were determined. The volumes and ash weights of the femurs and mandibles were estimated. Maximum loads of the femurs and mandibles were determined by using a three point bending test. Ovariectomy decreased bone mineral density of the femoral midshaft, however naproxen prevented this decrease. Neither ovariectomy nor naproxen treatment affected the BMD in the molar alveolar region. Maximum load was found significantly decreased in the femoral midshaft, however, naproxen treatment prevented this decrease. Maximum load of the molar alveolar region did not significantly change. Naproxen prevents the strength characteristics of femoral midshaft afforded by ovariectomy. However, neither ovariectomy nor naproxen has an effect on the molar alveolar region of the mandible.
author Turkozan,N. Y
Ulusoy,A. T
Balcioglu,H. A
Bal,F
Ozel,S
author_facet Turkozan,N. Y
Ulusoy,A. T
Balcioglu,H. A
Bal,F
Ozel,S
author_sort Turkozan,N. Y
title The Effects of Ovariectomy and Naproxen Treatment on the Strength of Femoral Midshaft and Molar Alveolar Region in Rats
title_short The Effects of Ovariectomy and Naproxen Treatment on the Strength of Femoral Midshaft and Molar Alveolar Region in Rats
title_full The Effects of Ovariectomy and Naproxen Treatment on the Strength of Femoral Midshaft and Molar Alveolar Region in Rats
title_fullStr The Effects of Ovariectomy and Naproxen Treatment on the Strength of Femoral Midshaft and Molar Alveolar Region in Rats
title_full_unstemmed The Effects of Ovariectomy and Naproxen Treatment on the Strength of Femoral Midshaft and Molar Alveolar Region in Rats
title_sort effects of ovariectomy and naproxen treatment on the strength of femoral midshaft and molar alveolar region in rats
publisher Sociedad Chilena de Anatomía
publishDate 2009
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300007
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