Immunohistochemical Study of Acute Effects of Ethanol on Midbrain of Wistar Rats Associated with the Date of Birth of Neurons in Encephalon

The verification of the acute effects of ethanol on the midbrain, which neurons are mainly formed in E14, will ratify if the acute effects of ethanol are associated, in terms of prevalence, to the date of birth of neurons in certain regions of the brain. The aim of this study was to determine the ef...

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Autores principales:	Lopes,Danielly Bandeira, Nascimento,Guilherme Nobre Lima do, Carvalho,Adryano Augustto Valladão de, Souza Neto,Advaldo Carlos de, Lima,Natácia Evangelista de, Aversi-Ferreira,Tales Alexandre
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2009
Materias:	Ethanol Brain Midbrain Neuronal migration Fetal Alcohol Syndrome
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300009
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spelling	oai:scielo:S0717-950220090003000092010-04-05Immunohistochemical Study of Acute Effects of Ethanol on Midbrain of Wistar Rats Associated with the Date of Birth of Neurons in EncephalonLopes,Danielly BandeiraNascimento,Guilherme Nobre Lima doCarvalho,Adryano Augustto Valladão deSouza Neto,Advaldo Carlos deLima,Natácia Evangelista deAversi-Ferreira,Tales Alexandre Ethanol Brain Midbrain Neuronal migration Fetal Alcohol Syndrome The verification of the acute effects of ethanol on the midbrain, which neurons are mainly formed in E14, will ratify if the acute effects of ethanol are associated, in terms of prevalence, to the date of birth of neurons in certain regions of the brain. The aim of this study was to determine the effects of acute exposure to ethanol on the neuronal density of the midbrain and to associate these results with acute effects of ethanol in other regions of the brain under the same conditions. The rats were treated with intraperitoneal ethanol during one day (E12) and 1h after the last ethanol injection was applied to BrdU. The animals were sacrificed; the brains were removed and sectioned. The sections were treated with DAB for the BrdU revelation, the slides were stained with safranin for one group and another group was stained with H & E. The effects of acute injection of ethanol in E12 on the midbrain were not detected in this study. Data from literature suggest that the deleterious action of acute ethanol consumption only occur if the drug is injected at times near the beginning of the migration of neurons in that particular region of the brain.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.27 n.3 20092009-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300009en10.4067/S0717-95022009000300009
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Ethanol Brain Midbrain Neuronal migration Fetal Alcohol Syndrome
spellingShingle	Ethanol Brain Midbrain Neuronal migration Fetal Alcohol Syndrome Lopes,Danielly Bandeira Nascimento,Guilherme Nobre Lima do Carvalho,Adryano Augustto Valladão de Souza Neto,Advaldo Carlos de Lima,Natácia Evangelista de Aversi-Ferreira,Tales Alexandre Immunohistochemical Study of Acute Effects of Ethanol on Midbrain of Wistar Rats Associated with the Date of Birth of Neurons in Encephalon
description	The verification of the acute effects of ethanol on the midbrain, which neurons are mainly formed in E14, will ratify if the acute effects of ethanol are associated, in terms of prevalence, to the date of birth of neurons in certain regions of the brain. The aim of this study was to determine the effects of acute exposure to ethanol on the neuronal density of the midbrain and to associate these results with acute effects of ethanol in other regions of the brain under the same conditions. The rats were treated with intraperitoneal ethanol during one day (E12) and 1h after the last ethanol injection was applied to BrdU. The animals were sacrificed; the brains were removed and sectioned. The sections were treated with DAB for the BrdU revelation, the slides were stained with safranin for one group and another group was stained with H & E. The effects of acute injection of ethanol in E12 on the midbrain were not detected in this study. Data from literature suggest that the deleterious action of acute ethanol consumption only occur if the drug is injected at times near the beginning of the migration of neurons in that particular region of the brain.
author	Lopes,Danielly Bandeira Nascimento,Guilherme Nobre Lima do Carvalho,Adryano Augustto Valladão de Souza Neto,Advaldo Carlos de Lima,Natácia Evangelista de Aversi-Ferreira,Tales Alexandre
author_facet	Lopes,Danielly Bandeira Nascimento,Guilherme Nobre Lima do Carvalho,Adryano Augustto Valladão de Souza Neto,Advaldo Carlos de Lima,Natácia Evangelista de Aversi-Ferreira,Tales Alexandre
author_sort	Lopes,Danielly Bandeira
title	Immunohistochemical Study of Acute Effects of Ethanol on Midbrain of Wistar Rats Associated with the Date of Birth of Neurons in Encephalon
title_short	Immunohistochemical Study of Acute Effects of Ethanol on Midbrain of Wistar Rats Associated with the Date of Birth of Neurons in Encephalon
title_full	Immunohistochemical Study of Acute Effects of Ethanol on Midbrain of Wistar Rats Associated with the Date of Birth of Neurons in Encephalon
title_fullStr	Immunohistochemical Study of Acute Effects of Ethanol on Midbrain of Wistar Rats Associated with the Date of Birth of Neurons in Encephalon
title_full_unstemmed	Immunohistochemical Study of Acute Effects of Ethanol on Midbrain of Wistar Rats Associated with the Date of Birth of Neurons in Encephalon
title_sort	immunohistochemical study of acute effects of ethanol on midbrain of wistar rats associated with the date of birth of neurons in encephalon
publisher	Sociedad Chilena de Anatomía
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300009
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Immunohistochemical Study of Acute Effects of Ethanol on Midbrain of Wistar Rats Associated with the Date of Birth of Neurons in Encephalon

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