Chronic Stress Effects on NPY Neuronal Population During Rat Development

The aim of this work was to determine the chronical stress effects on the encephalic NPY neurons population during the fetal Central nervous system development. Immunocytochemical techniques were used for this purpose: NPY neurons presented a similar morphology during the gestation days studied but...

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Autores principales:	Buljubacich,Karina Alejandra, Mugnaini,María Teresa, Soñez,Carlos Alberto, Rolando,Alicia Nélida, Romanini,María Cristina, Bozzo,Aída Andrea, Soñez,María Cristina, Gauna,Héctor Fernando
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2009
Materias:	NPY Prenatal chronical stress CNS Rats
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300039
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spelling	oai:scielo:S0717-950220090003000392010-04-05Chronic Stress Effects on NPY Neuronal Population During Rat DevelopmentBuljubacich,Karina AlejandraMugnaini,María TeresaSoñez,Carlos AlbertoRolando,Alicia NélidaRomanini,María CristinaBozzo,Aída AndreaSoñez,María CristinaGauna,Héctor Fernando NPY Prenatal chronical stress CNS Rats The aim of this work was to determine the chronical stress effects on the encephalic NPY neurons population during the fetal Central nervous system development. Immunocytochemical techniques were used for this purpose: NPY neurons presented a similar morphology during the gestation days studied but their distribution varied in the anterior, medium and posterior brain. Statistical Highly significant differences in number of NPY positive neurons (p<0.01) among anterior, medium and posterior brain of stressed fetus (SF) were determined depending on the gestation period and the brain area. The NPY neurons were increased in ARC (Arcuate Hypothalamic Nucleus), PH (Posterior Hypothalamic Area) and DM (Dorsomedial Hypothalamic Nucleus) in stressed fetuses (SF) of 17 days, and in ARC of 19 days SF (p< 0.01) were detected in the different brain nucleus. The NPY population increased in PnO (Pontine Reticular Nu, Oral Part) and RITg (Reticulotegmental Nu of the Pons) of 17 days SF, while they were detected in posterior brain at Pyx (Pyramidal Decussation), Rob (Raphe Obscurus Nucleus) and RPA (Raphe Pallidus Nucleus) in SF of 19 days. They also increased in number (p<0.05) in DPGI (Dorsal Paragigantocellular Nu), CGPn (Central Gray of Pons) and PrH (Prepositus Hypoglossal Nucleus) of 17 days SF. Finally, any statistical differences were found among CF and SF in the following nuclei: anterior brain, AH (Anterior Hypothalamic Nucleus), DM (Dorsomedia L Hypothalamic Nucleus) of 17 days; ME (Median Eminence)., VMH (Ventromedial Hypothalamic Nucleus) of 19 days; medium brain in CG (Central Periaqueductal Gray), DR (Dorsal Raphe Nucleus) of 17 days and posterior brain in PnC (Pontine Reticular Nu, Caudal Part), PrH (Prepositus Hypoglossal Nucleus), RMgG (Raphe Magnus Nucleus), IO (Inferior Olive) of 17 days. The increase number of NPY neurons found in the stressed rat fetuses in all periods studied would indicate the participation of the NPY System in the regulation of H.H.A axis.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.27 n.3 20092009-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300039en10.4067/S0717-95022009000300039
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	NPY Prenatal chronical stress CNS Rats
spellingShingle	NPY Prenatal chronical stress CNS Rats Buljubacich,Karina Alejandra Mugnaini,María Teresa Soñez,Carlos Alberto Rolando,Alicia Nélida Romanini,María Cristina Bozzo,Aída Andrea Soñez,María Cristina Gauna,Héctor Fernando Chronic Stress Effects on NPY Neuronal Population During Rat Development
description	The aim of this work was to determine the chronical stress effects on the encephalic NPY neurons population during the fetal Central nervous system development. Immunocytochemical techniques were used for this purpose: NPY neurons presented a similar morphology during the gestation days studied but their distribution varied in the anterior, medium and posterior brain. Statistical Highly significant differences in number of NPY positive neurons (p<0.01) among anterior, medium and posterior brain of stressed fetus (SF) were determined depending on the gestation period and the brain area. The NPY neurons were increased in ARC (Arcuate Hypothalamic Nucleus), PH (Posterior Hypothalamic Area) and DM (Dorsomedial Hypothalamic Nucleus) in stressed fetuses (SF) of 17 days, and in ARC of 19 days SF (p< 0.01) were detected in the different brain nucleus. The NPY population increased in PnO (Pontine Reticular Nu, Oral Part) and RITg (Reticulotegmental Nu of the Pons) of 17 days SF, while they were detected in posterior brain at Pyx (Pyramidal Decussation), Rob (Raphe Obscurus Nucleus) and RPA (Raphe Pallidus Nucleus) in SF of 19 days. They also increased in number (p<0.05) in DPGI (Dorsal Paragigantocellular Nu), CGPn (Central Gray of Pons) and PrH (Prepositus Hypoglossal Nucleus) of 17 days SF. Finally, any statistical differences were found among CF and SF in the following nuclei: anterior brain, AH (Anterior Hypothalamic Nucleus), DM (Dorsomedia L Hypothalamic Nucleus) of 17 days; ME (Median Eminence)., VMH (Ventromedial Hypothalamic Nucleus) of 19 days; medium brain in CG (Central Periaqueductal Gray), DR (Dorsal Raphe Nucleus) of 17 days and posterior brain in PnC (Pontine Reticular Nu, Caudal Part), PrH (Prepositus Hypoglossal Nucleus), RMgG (Raphe Magnus Nucleus), IO (Inferior Olive) of 17 days. The increase number of NPY neurons found in the stressed rat fetuses in all periods studied would indicate the participation of the NPY System in the regulation of H.H.A axis.
author	Buljubacich,Karina Alejandra Mugnaini,María Teresa Soñez,Carlos Alberto Rolando,Alicia Nélida Romanini,María Cristina Bozzo,Aída Andrea Soñez,María Cristina Gauna,Héctor Fernando
author_facet	Buljubacich,Karina Alejandra Mugnaini,María Teresa Soñez,Carlos Alberto Rolando,Alicia Nélida Romanini,María Cristina Bozzo,Aída Andrea Soñez,María Cristina Gauna,Héctor Fernando
author_sort	Buljubacich,Karina Alejandra
title	Chronic Stress Effects on NPY Neuronal Population During Rat Development
title_short	Chronic Stress Effects on NPY Neuronal Population During Rat Development
title_full	Chronic Stress Effects on NPY Neuronal Population During Rat Development
title_fullStr	Chronic Stress Effects on NPY Neuronal Population During Rat Development
title_full_unstemmed	Chronic Stress Effects on NPY Neuronal Population During Rat Development
title_sort	chronic stress effects on npy neuronal population during rat development
publisher	Sociedad Chilena de Anatomía
publishDate	2009
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000300039
work_keys_str_mv	AT buljubacichkarinaalejandra chronicstresseffectsonnpyneuronalpopulationduringratdevelopment AT mugnainimariateresa chronicstresseffectsonnpyneuronalpopulationduringratdevelopment AT sonezcarlosalberto chronicstresseffectsonnpyneuronalpopulationduringratdevelopment AT rolandoalicianelida chronicstresseffectsonnpyneuronalpopulationduringratdevelopment AT romaninimariacristina chronicstresseffectsonnpyneuronalpopulationduringratdevelopment AT bozzoaidaandrea chronicstresseffectsonnpyneuronalpopulationduringratdevelopment AT sonezmariacristina chronicstresseffectsonnpyneuronalpopulationduringratdevelopment AT gaunahectorfernando chronicstresseffectsonnpyneuronalpopulationduringratdevelopment
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Chronic Stress Effects on NPY Neuronal Population During Rat Development

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