Resistance of CA1 Pyramidal Cells to STZ-Induced Diabetes in Young Rats

The pyramidal cell density of CA1 hippocampal subfield following STZ-induced diabetes in young rats were studied. 12 male albino 6-week Wistar rats were allocated equally in groups of normal and diabetic. Hyperglycemia induced by Streptozotocin (80 mg/kg) in animals of diabetic group. After 5 weeks...

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Autores principales: Fazeli,Seyyed Amirhossein, Gharravi,Anneh Mohammad, Jahanshahi,Mehrdad, Ghafari,Soraya, Behnampour,Naser, Golalipour,Mohammad Jafar
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2009
Materias:
CA1
Rat
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000400006
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spelling oai:scielo:S0717-950220090004000062010-05-18Resistance of CA1 Pyramidal Cells to STZ-Induced Diabetes in Young RatsFazeli,Seyyed AmirhosseinGharravi,Anneh MohammadJahanshahi,MehrdadGhafari,SorayaBehnampour,NaserGolalipour,Mohammad Jafar Pyramidal cell density CA1 Hippocampus Diabetes Rat The pyramidal cell density of CA1 hippocampal subfield following STZ-induced diabetes in young rats were studied. 12 male albino 6-week Wistar rats were allocated equally in groups of normal and diabetic. Hyperglycemia induced by Streptozotocin (80 mg/kg) in animals of diabetic group. After 5 weeks of study, all the rats were sacrificed and coronal sections were taken from dorsal hippocampal formation of the right cerebral hemispheres and stained with crysel violet. The area densities of the CA1 pyramidal cells were measured and compared among two groups. No significant difference between the densities of two experimental groups was found. The results can arise from the short period of diabetes and also the possible regenerative processes in developing brain of the young diabetic rats which compensated significant diabetes-induced neuronal loss.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.27 n.4 20092009-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000400006en10.4067/S0717-95022009000400006
institution Scielo Chile
collection Scielo Chile
language English
topic Pyramidal cell density
CA1
Hippocampus
Diabetes
Rat
spellingShingle Pyramidal cell density
CA1
Hippocampus
Diabetes
Rat
Fazeli,Seyyed Amirhossein
Gharravi,Anneh Mohammad
Jahanshahi,Mehrdad
Ghafari,Soraya
Behnampour,Naser
Golalipour,Mohammad Jafar
Resistance of CA1 Pyramidal Cells to STZ-Induced Diabetes in Young Rats
description The pyramidal cell density of CA1 hippocampal subfield following STZ-induced diabetes in young rats were studied. 12 male albino 6-week Wistar rats were allocated equally in groups of normal and diabetic. Hyperglycemia induced by Streptozotocin (80 mg/kg) in animals of diabetic group. After 5 weeks of study, all the rats were sacrificed and coronal sections were taken from dorsal hippocampal formation of the right cerebral hemispheres and stained with crysel violet. The area densities of the CA1 pyramidal cells were measured and compared among two groups. No significant difference between the densities of two experimental groups was found. The results can arise from the short period of diabetes and also the possible regenerative processes in developing brain of the young diabetic rats which compensated significant diabetes-induced neuronal loss.
author Fazeli,Seyyed Amirhossein
Gharravi,Anneh Mohammad
Jahanshahi,Mehrdad
Ghafari,Soraya
Behnampour,Naser
Golalipour,Mohammad Jafar
author_facet Fazeli,Seyyed Amirhossein
Gharravi,Anneh Mohammad
Jahanshahi,Mehrdad
Ghafari,Soraya
Behnampour,Naser
Golalipour,Mohammad Jafar
author_sort Fazeli,Seyyed Amirhossein
title Resistance of CA1 Pyramidal Cells to STZ-Induced Diabetes in Young Rats
title_short Resistance of CA1 Pyramidal Cells to STZ-Induced Diabetes in Young Rats
title_full Resistance of CA1 Pyramidal Cells to STZ-Induced Diabetes in Young Rats
title_fullStr Resistance of CA1 Pyramidal Cells to STZ-Induced Diabetes in Young Rats
title_full_unstemmed Resistance of CA1 Pyramidal Cells to STZ-Induced Diabetes in Young Rats
title_sort resistance of ca1 pyramidal cells to stz-induced diabetes in young rats
publisher Sociedad Chilena de Anatomía
publishDate 2009
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022009000400006
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