Inmunohistochemical Evaluation of Estrogen Receptors Alpha and Beta in Normal Inferior Turbinate Mucosa

It has been postulated that the nasal mucosa, like other human tissues, is affected by a complex interactive network of neuropeptides, cytokines, allergic and inflammatory mediators and hormones such as estrogen, in which associations between symptoms (e.g. nasal stuffiness and coryza) and hormonal...

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Autores principales:	Millas,Ieda, Liquidato,Bianca Maria, Dolci,José Eduardo Lutaif, Macéa,José Rafael, Fregnani,José Humberto Tavares Guerreiro, Meceles,Lenira Rocha
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2010
Materias:	Rhinitis Estrogen receptors Estrogens Nasal mucosa Hormones Immunohistochemistry
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000100020
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spelling	oai:scielo:S0717-950220100001000202010-07-05Inmunohistochemical Evaluation of Estrogen Receptors Alpha and Beta in Normal Inferior Turbinate MucosaMillas,IedaLiquidato,Bianca MariaDolci,José Eduardo LutaifMacéa,José RafaelFregnani,José Humberto Tavares GuerreiroMeceles,Lenira Rocha Rhinitis Estrogen receptors Estrogens Nasal mucosa Hormones Immunohistochemistry It has been postulated that the nasal mucosa, like other human tissues, is affected by a complex interactive network of neuropeptides, cytokines, allergic and inflammatory mediators and hormones such as estrogen, in which associations between symptoms (e.g. nasal stuffiness and coryza) and hormonal variations deriving from pregnancy, use of hormonal contraceptives and menstrual cycle phases are observed. The objective is evaluating the presence of specific estrogen receptors (types alpha and beta) in inferior turbinate mucosa in healthy subjects without nasal symptoms. Samples of nasal inferior turbinate were removed from patients undergoing aesthetic nasal surgery, and analyzed using hematoxylin-eosin staining, followed by immunohistochemical preparations on paraffin-embedded sections from the material sample, to detect estrogen receptors alpha and beta. Positive immunohistochemical reactions for both beta and alpha receptors were found in various regions of the inferior nasal turbinate. In conclusion both alpha and beta receptors were found, though the expression of beta was greater and more intense in the anterior portion of the inferior turbinate. No difference was found between male and female patients regarding the intensity of expression of receptors in the inferior turbinate.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.28 n.1 20102010-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000100020en10.4067/S0717-95022010000100020
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Rhinitis Estrogen receptors Estrogens Nasal mucosa Hormones Immunohistochemistry
spellingShingle	Rhinitis Estrogen receptors Estrogens Nasal mucosa Hormones Immunohistochemistry Millas,Ieda Liquidato,Bianca Maria Dolci,José Eduardo Lutaif Macéa,José Rafael Fregnani,José Humberto Tavares Guerreiro Meceles,Lenira Rocha Inmunohistochemical Evaluation of Estrogen Receptors Alpha and Beta in Normal Inferior Turbinate Mucosa
description	It has been postulated that the nasal mucosa, like other human tissues, is affected by a complex interactive network of neuropeptides, cytokines, allergic and inflammatory mediators and hormones such as estrogen, in which associations between symptoms (e.g. nasal stuffiness and coryza) and hormonal variations deriving from pregnancy, use of hormonal contraceptives and menstrual cycle phases are observed. The objective is evaluating the presence of specific estrogen receptors (types alpha and beta) in inferior turbinate mucosa in healthy subjects without nasal symptoms. Samples of nasal inferior turbinate were removed from patients undergoing aesthetic nasal surgery, and analyzed using hematoxylin-eosin staining, followed by immunohistochemical preparations on paraffin-embedded sections from the material sample, to detect estrogen receptors alpha and beta. Positive immunohistochemical reactions for both beta and alpha receptors were found in various regions of the inferior nasal turbinate. In conclusion both alpha and beta receptors were found, though the expression of beta was greater and more intense in the anterior portion of the inferior turbinate. No difference was found between male and female patients regarding the intensity of expression of receptors in the inferior turbinate.
author	Millas,Ieda Liquidato,Bianca Maria Dolci,José Eduardo Lutaif Macéa,José Rafael Fregnani,José Humberto Tavares Guerreiro Meceles,Lenira Rocha
author_facet	Millas,Ieda Liquidato,Bianca Maria Dolci,José Eduardo Lutaif Macéa,José Rafael Fregnani,José Humberto Tavares Guerreiro Meceles,Lenira Rocha
author_sort	Millas,Ieda
title	Inmunohistochemical Evaluation of Estrogen Receptors Alpha and Beta in Normal Inferior Turbinate Mucosa
title_short	Inmunohistochemical Evaluation of Estrogen Receptors Alpha and Beta in Normal Inferior Turbinate Mucosa
title_full	Inmunohistochemical Evaluation of Estrogen Receptors Alpha and Beta in Normal Inferior Turbinate Mucosa
title_fullStr	Inmunohistochemical Evaluation of Estrogen Receptors Alpha and Beta in Normal Inferior Turbinate Mucosa
title_full_unstemmed	Inmunohistochemical Evaluation of Estrogen Receptors Alpha and Beta in Normal Inferior Turbinate Mucosa
title_sort	inmunohistochemical evaluation of estrogen receptors alpha and beta in normal inferior turbinate mucosa
publisher	Sociedad Chilena de Anatomía
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000100020
work_keys_str_mv	AT millasieda inmunohistochemicalevaluationofestrogenreceptorsalphaandbetainnormalinferiorturbinatemucosa AT liquidatobiancamaria inmunohistochemicalevaluationofestrogenreceptorsalphaandbetainnormalinferiorturbinatemucosa AT dolcijoseeduardolutaif inmunohistochemicalevaluationofestrogenreceptorsalphaandbetainnormalinferiorturbinatemucosa AT maceajoserafael inmunohistochemicalevaluationofestrogenreceptorsalphaandbetainnormalinferiorturbinatemucosa AT fregnanijosehumbertotavaresguerreiro inmunohistochemicalevaluationofestrogenreceptorsalphaandbetainnormalinferiorturbinatemucosa AT meceleslenirarocha inmunohistochemicalevaluationofestrogenreceptorsalphaandbetainnormalinferiorturbinatemucosa
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Inmunohistochemical Evaluation of Estrogen Receptors Alpha and Beta in Normal Inferior Turbinate Mucosa

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