Cellular Changes in the Placenta in Pregnancies Complicated with Diabetes

Placenta is the most accurate record of the infant prenatal experience. After delivery if the placenta is examined minutely, it provides much insight into the prenatal health of the baby and the mother. In diabetic pregnancy, placental weight is higher in comparison to normal pregnancy. To study the...

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Autores principales:	Verma,Ranjana, Mishra,Sabita, Kaul,Jagat Mohini
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2010
Materias:	Placenta Gross Gestational diabetes Microscopy
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000100038
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spelling	oai:scielo:S0717-950220100001000382010-07-05Cellular Changes in the Placenta in Pregnancies Complicated with DiabetesVerma,RanjanaMishra,SabitaKaul,Jagat Mohini Placenta Gross Gestational diabetes Microscopy Placenta is the most accurate record of the infant prenatal experience. After delivery if the placenta is examined minutely, it provides much insight into the prenatal health of the baby and the mother. In diabetic pregnancy, placental weight is higher in comparison to normal pregnancy. To study the cellular differences that might contribute to larger size of placenta, light microscopic analysis was performed on 25 full term placentas, out of which 20 were of Gestational diabetes mellitus (12 controlled on diet, 8 controlled on insulin) and 5 control group. Tissue sections were processed and analyzed. Birth weight of neonate, placental weight, vascular pattern of chorionic blood vessels and site of attachment of umbilical cord were recorded. In the placenta of diabetic pregnants, gross abnormalities were uncommon but microscopic examination exhibited, to a varying degree, lesions like syncytial knots, fibrinoid necrosis, villous edema, villous fibrosis and capillary proliferation. These findings indicate that control of hyperglycemia only partially prevents the development of placental abnormalities which must be due to some other constituent factor of diabetic state.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.28 n.1 20102010-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000100038en10.4067/S0717-95022010000100038
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Placenta Gross Gestational diabetes Microscopy
spellingShingle	Placenta Gross Gestational diabetes Microscopy Verma,Ranjana Mishra,Sabita Kaul,Jagat Mohini Cellular Changes in the Placenta in Pregnancies Complicated with Diabetes
description	Placenta is the most accurate record of the infant prenatal experience. After delivery if the placenta is examined minutely, it provides much insight into the prenatal health of the baby and the mother. In diabetic pregnancy, placental weight is higher in comparison to normal pregnancy. To study the cellular differences that might contribute to larger size of placenta, light microscopic analysis was performed on 25 full term placentas, out of which 20 were of Gestational diabetes mellitus (12 controlled on diet, 8 controlled on insulin) and 5 control group. Tissue sections were processed and analyzed. Birth weight of neonate, placental weight, vascular pattern of chorionic blood vessels and site of attachment of umbilical cord were recorded. In the placenta of diabetic pregnants, gross abnormalities were uncommon but microscopic examination exhibited, to a varying degree, lesions like syncytial knots, fibrinoid necrosis, villous edema, villous fibrosis and capillary proliferation. These findings indicate that control of hyperglycemia only partially prevents the development of placental abnormalities which must be due to some other constituent factor of diabetic state.
author	Verma,Ranjana Mishra,Sabita Kaul,Jagat Mohini
author_facet	Verma,Ranjana Mishra,Sabita Kaul,Jagat Mohini
author_sort	Verma,Ranjana
title	Cellular Changes in the Placenta in Pregnancies Complicated with Diabetes
title_short	Cellular Changes in the Placenta in Pregnancies Complicated with Diabetes
title_full	Cellular Changes in the Placenta in Pregnancies Complicated with Diabetes
title_fullStr	Cellular Changes in the Placenta in Pregnancies Complicated with Diabetes
title_full_unstemmed	Cellular Changes in the Placenta in Pregnancies Complicated with Diabetes
title_sort	cellular changes in the placenta in pregnancies complicated with diabetes
publisher	Sociedad Chilena de Anatomía
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000100038
work_keys_str_mv	AT vermaranjana cellularchangesintheplacentainpregnanciescomplicatedwithdiabetes AT mishrasabita cellularchangesintheplacentainpregnanciescomplicatedwithdiabetes AT kauljagatmohini cellularchangesintheplacentainpregnanciescomplicatedwithdiabetes
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Cellular Changes in the Placenta in Pregnancies Complicated with Diabetes

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