Sex Chromatin in Dental Pulp: Performance of Diagnosis Test and Gold Standard Generation

The sex chromatin or Barr body is a condensation of chromatin present at the nucleus of cells in female individuals. Their observation is possible in different cell types and is used for the rapid diagnosis of biological sex. The observation of this condensation in cells of the pulp tissue can be us...

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Autores principales:	Suazo Galdames,Iván, Roa Henríquez,Ignacio, Cantín L,Mario
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2010
Materias:	Sex chromatin Barr chromatin Sex determination Forensic dentistry
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000400017
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spelling	oai:scielo:S0717-950220100004000172011-03-31Sex Chromatin in Dental Pulp: Performance of Diagnosis Test and Gold Standard GenerationSuazo Galdames,IvánRoa Henríquez,IgnacioCantín L,Mario Sex chromatin Barr chromatin Sex determination Forensic dentistry The sex chromatin or Barr body is a condensation of chromatin present at the nucleus of cells in female individuals. Their observation is possible in different cell types and is used for the rapid diagnosis of biological sex. The observation of this condensation in cells of the pulp tissue can be useful in the forensic diagnosis of sex, primarily because of the protection it give dental hard tissues, but its diagnostic value has not been tested. The purpose of this study is to analyze the diagnostic value of the observation of sex chromatin in cells of the pulp tissue. We used 40 premolars and third molars20 from men with a mean age of 20.6 years (SD 8.8) and 20 from women with a mean age of 20.4 years (SD 7.4). The pulp was obtained from teeth extracted and localized 50 cells per plate. The presence of a cell with visible Barr body was considered positive for women. With these results, we evaluated the diagnostic performance of the test. The performance of the test was 100%; of the 50 cells observed per plate, mean Barr bodies positive cells was 20.4 (SD 0.44) in female samples. There was no positive cell in preparations of male subjects. The diagnostic test observation of sex chromatin in dental pulp is a reliable test for sex determination. This study provides a gold standard for performance assessment in which the teeth have suffered extreme physical conditions, such as incineration and dumping.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.28 n.4 20102010-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000400017en10.4067/S0717-95022010000400017
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Sex chromatin Barr chromatin Sex determination Forensic dentistry
spellingShingle	Sex chromatin Barr chromatin Sex determination Forensic dentistry Suazo Galdames,Iván Roa Henríquez,Ignacio Cantín L,Mario Sex Chromatin in Dental Pulp: Performance of Diagnosis Test and Gold Standard Generation
description	The sex chromatin or Barr body is a condensation of chromatin present at the nucleus of cells in female individuals. Their observation is possible in different cell types and is used for the rapid diagnosis of biological sex. The observation of this condensation in cells of the pulp tissue can be useful in the forensic diagnosis of sex, primarily because of the protection it give dental hard tissues, but its diagnostic value has not been tested. The purpose of this study is to analyze the diagnostic value of the observation of sex chromatin in cells of the pulp tissue. We used 40 premolars and third molars20 from men with a mean age of 20.6 years (SD 8.8) and 20 from women with a mean age of 20.4 years (SD 7.4). The pulp was obtained from teeth extracted and localized 50 cells per plate. The presence of a cell with visible Barr body was considered positive for women. With these results, we evaluated the diagnostic performance of the test. The performance of the test was 100%; of the 50 cells observed per plate, mean Barr bodies positive cells was 20.4 (SD 0.44) in female samples. There was no positive cell in preparations of male subjects. The diagnostic test observation of sex chromatin in dental pulp is a reliable test for sex determination. This study provides a gold standard for performance assessment in which the teeth have suffered extreme physical conditions, such as incineration and dumping.
author	Suazo Galdames,Iván Roa Henríquez,Ignacio Cantín L,Mario
author_facet	Suazo Galdames,Iván Roa Henríquez,Ignacio Cantín L,Mario
author_sort	Suazo Galdames,Iván
title	Sex Chromatin in Dental Pulp: Performance of Diagnosis Test and Gold Standard Generation
title_short	Sex Chromatin in Dental Pulp: Performance of Diagnosis Test and Gold Standard Generation
title_full	Sex Chromatin in Dental Pulp: Performance of Diagnosis Test and Gold Standard Generation
title_fullStr	Sex Chromatin in Dental Pulp: Performance of Diagnosis Test and Gold Standard Generation
title_full_unstemmed	Sex Chromatin in Dental Pulp: Performance of Diagnosis Test and Gold Standard Generation
title_sort	sex chromatin in dental pulp: performance of diagnosis test and gold standard generation
publisher	Sociedad Chilena de Anatomía
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000400017
work_keys_str_mv	AT suazogaldamesivan sexchromatinindentalpulpperformanceofdiagnosistestandgoldstandardgeneration AT roahenriquezignacio sexchromatinindentalpulpperformanceofdiagnosistestandgoldstandardgeneration AT cantinlmario sexchromatinindentalpulpperformanceofdiagnosistestandgoldstandardgeneration
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Sex Chromatin in Dental Pulp: Performance of Diagnosis Test and Gold Standard Generation

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