Histopathological Effects of Aloe barbadensis and Soybean Oil on Rat Liver

Aloe Barbadensis, which is a species of Aloe vera, is a popular plant used by the common people and in alternative medicine. This study aimed to analyze the effects of Aloe Barbadensis and soybean oil on liver. For this study Wistar Albino female rats were taken and divided into 3 equal groups; the...

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Autores principales:	Kosif,Rengin, Yilmaz,Fahri, Evrendilek,Gülsün Akdemir, Diramali,Murat
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2010
Materias:	Aloe barbadensis Soybean Rat Liver Effect
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000400019
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spelling	oai:scielo:S0717-950220100004000192011-03-31Histopathological Effects of Aloe barbadensis and Soybean Oil on Rat LiverKosif,RenginYilmaz,FahriEvrendilek,Gülsün AkdemirDiramali,Murat Aloe barbadensis Soybean Rat Liver Effect Aloe Barbadensis, which is a species of Aloe vera, is a popular plant used by the common people and in alternative medicine. This study aimed to analyze the effects of Aloe Barbadensis and soybean oil on liver. For this study Wistar Albino female rats were taken and divided into 3 equal groups; the first group was the control group wherein no treatment was applied, second group in which the dissolved form of A. barbadensis in the soybean oil was applied (25 mg/day), and the third group which only soybean oil was applied (500 mg/day). Biopsy materials were taken from the lobus dexter of the livers of the rats and analyzed with light microscope after the necessary standard processing of histologic slides. Group I demonstrated normal structural characteristics of rat liver. In Group II and Group III, we observed nuclear enlargement, mild increase in chromatin and hydropic degeneration and binucleation in some hepatocytes. Liver histology demonstrated congestion in portal veins, sinusoids and the central veins. Merely in Group III, portal venous congestion and in Group II sinusoidal congestion was evident parenchyma of the liver. Additionally in Group III liver histology demonstrated plasmocyte infiltration in portal areas. Our study showed that using soybean with Aloe Barbadensis is synergystic and increasing each others effects. However we didn't observe mononeuclear infiltrations in Group II, these show antinflammatory effects of Aloe Barbadensis. It is determined that, depending on the used dose of Aloe Barbadensis, the toxic effect can change. If Aloe Barbadensis used very high doses it can have toxic effect on hepatocytes.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.28 n.4 20102010-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000400019en10.4067/S0717-95022010000400019
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Aloe barbadensis Soybean Rat Liver Effect
spellingShingle	Aloe barbadensis Soybean Rat Liver Effect Kosif,Rengin Yilmaz,Fahri Evrendilek,Gülsün Akdemir Diramali,Murat Histopathological Effects of Aloe barbadensis and Soybean Oil on Rat Liver
description	Aloe Barbadensis, which is a species of Aloe vera, is a popular plant used by the common people and in alternative medicine. This study aimed to analyze the effects of Aloe Barbadensis and soybean oil on liver. For this study Wistar Albino female rats were taken and divided into 3 equal groups; the first group was the control group wherein no treatment was applied, second group in which the dissolved form of A. barbadensis in the soybean oil was applied (25 mg/day), and the third group which only soybean oil was applied (500 mg/day). Biopsy materials were taken from the lobus dexter of the livers of the rats and analyzed with light microscope after the necessary standard processing of histologic slides. Group I demonstrated normal structural characteristics of rat liver. In Group II and Group III, we observed nuclear enlargement, mild increase in chromatin and hydropic degeneration and binucleation in some hepatocytes. Liver histology demonstrated congestion in portal veins, sinusoids and the central veins. Merely in Group III, portal venous congestion and in Group II sinusoidal congestion was evident parenchyma of the liver. Additionally in Group III liver histology demonstrated plasmocyte infiltration in portal areas. Our study showed that using soybean with Aloe Barbadensis is synergystic and increasing each others effects. However we didn't observe mononeuclear infiltrations in Group II, these show antinflammatory effects of Aloe Barbadensis. It is determined that, depending on the used dose of Aloe Barbadensis, the toxic effect can change. If Aloe Barbadensis used very high doses it can have toxic effect on hepatocytes.
author	Kosif,Rengin Yilmaz,Fahri Evrendilek,Gülsün Akdemir Diramali,Murat
author_facet	Kosif,Rengin Yilmaz,Fahri Evrendilek,Gülsün Akdemir Diramali,Murat
author_sort	Kosif,Rengin
title	Histopathological Effects of Aloe barbadensis and Soybean Oil on Rat Liver
title_short	Histopathological Effects of Aloe barbadensis and Soybean Oil on Rat Liver
title_full	Histopathological Effects of Aloe barbadensis and Soybean Oil on Rat Liver
title_fullStr	Histopathological Effects of Aloe barbadensis and Soybean Oil on Rat Liver
title_full_unstemmed	Histopathological Effects of Aloe barbadensis and Soybean Oil on Rat Liver
title_sort	histopathological effects of aloe barbadensis and soybean oil on rat liver
publisher	Sociedad Chilena de Anatomía
publishDate	2010
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022010000400019
work_keys_str_mv	AT kosifrengin histopathologicaleffectsofaloebarbadensisandsoybeanoilonratliver AT yilmazfahri histopathologicaleffectsofaloebarbadensisandsoybeanoilonratliver AT evrendilekgulsunakdemir histopathologicaleffectsofaloebarbadensisandsoybeanoilonratliver AT diramalimurat histopathologicaleffectsofaloebarbadensisandsoybeanoilonratliver
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Histopathological Effects of Aloe barbadensis and Soybean Oil on Rat Liver

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