Effect of Aspirin on the Developing Teeth of Neonates

The objective of the present study was to evaluate the effect of aspirin (Acetyl Salicylic Acid) on the developing teeth of the fetus while the mothers were treated through out the pregnancy. Aspirin is a widely used analgesic and antipyretic drug used for symptomatic treatment. However, recent anim...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Nazir,Shakila, Naqvi,Sayed Naeem-ul-Hasan, Ahmed,Masood, Arain,Abdul Hakeem, Nazir,Naema
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2011
Materias:	Aspirin Teratogenic effect Dentition Female rabbits
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000100046
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0717-95022011000100046
record_format	dspace
spelling	oai:scielo:S0717-950220110001000462011-09-21Effect of Aspirin on the Developing Teeth of NeonatesNazir,ShakilaNaqvi,Sayed Naeem-ul-HasanAhmed,MasoodArain,Abdul HakeemNazir,Naema Aspirin Teratogenic effect Dentition Female rabbits The objective of the present study was to evaluate the effect of aspirin (Acetyl Salicylic Acid) on the developing teeth of the fetus while the mothers were treated through out the pregnancy. Aspirin is a widely used analgesic and antipyretic drug used for symptomatic treatment. However, recent animal studies have indicated a potent teratogenicity of Acetyl Salicylic Acid. Its easy availability without prescription has been associated with high possibility of misuse, especially in the developing world. An experimental control study was carried out where female rabbits being treated with aspirin were taken as mammalian model, and their offspring were used to evaluate the developmental defects in teeth. Quantitative analysis of minerals in three types of the sample teeth, was done using scanning electron microscope and energy dispersive X-ray spectroscopy (SEM-EDX). Calcium was the most affected mineral and incisors and mandibular molars were found to be the most affected teeth. Voluminous variations were observed in the mineral contents of samples from the treated and control group, however, significant results could not be achieved. A larger sample size could possibly be needed to produce more conclusive results.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.29 n.1 20112011-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000100046en10.4067/S0717-95022011000100046
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Aspirin Teratogenic effect Dentition Female rabbits
spellingShingle	Aspirin Teratogenic effect Dentition Female rabbits Nazir,Shakila Naqvi,Sayed Naeem-ul-Hasan Ahmed,Masood Arain,Abdul Hakeem Nazir,Naema Effect of Aspirin on the Developing Teeth of Neonates
description	The objective of the present study was to evaluate the effect of aspirin (Acetyl Salicylic Acid) on the developing teeth of the fetus while the mothers were treated through out the pregnancy. Aspirin is a widely used analgesic and antipyretic drug used for symptomatic treatment. However, recent animal studies have indicated a potent teratogenicity of Acetyl Salicylic Acid. Its easy availability without prescription has been associated with high possibility of misuse, especially in the developing world. An experimental control study was carried out where female rabbits being treated with aspirin were taken as mammalian model, and their offspring were used to evaluate the developmental defects in teeth. Quantitative analysis of minerals in three types of the sample teeth, was done using scanning electron microscope and energy dispersive X-ray spectroscopy (SEM-EDX). Calcium was the most affected mineral and incisors and mandibular molars were found to be the most affected teeth. Voluminous variations were observed in the mineral contents of samples from the treated and control group, however, significant results could not be achieved. A larger sample size could possibly be needed to produce more conclusive results.
author	Nazir,Shakila Naqvi,Sayed Naeem-ul-Hasan Ahmed,Masood Arain,Abdul Hakeem Nazir,Naema
author_facet	Nazir,Shakila Naqvi,Sayed Naeem-ul-Hasan Ahmed,Masood Arain,Abdul Hakeem Nazir,Naema
author_sort	Nazir,Shakila
title	Effect of Aspirin on the Developing Teeth of Neonates
title_short	Effect of Aspirin on the Developing Teeth of Neonates
title_full	Effect of Aspirin on the Developing Teeth of Neonates
title_fullStr	Effect of Aspirin on the Developing Teeth of Neonates
title_full_unstemmed	Effect of Aspirin on the Developing Teeth of Neonates
title_sort	effect of aspirin on the developing teeth of neonates
publisher	Sociedad Chilena de Anatomía
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000100046
work_keys_str_mv	AT nazirshakila effectofaspirinonthedevelopingteethofneonates AT naqvisayednaeemulhasan effectofaspirinonthedevelopingteethofneonates AT ahmedmasood effectofaspirinonthedevelopingteethofneonates AT arainabdulhakeem effectofaspirinonthedevelopingteethofneonates AT nazirnaema effectofaspirinonthedevelopingteethofneonates
_version_	1718444725775630336

Effect of Aspirin on the Developing Teeth of Neonates

Ejemplares similares