Histological Evaluation of Bone Regeneration Means Freeze Dried Bone Allograft (FDBA) in Post Exodontia Sockets

Within oral rehabilitation alveolar ridge preservation following extraction is important. This research study shows a histological, histochemical and histomorphometrical evaluation in two cases of post extraction ridge-socket preservation performed with FDBA. In two patients dental extraction proced...

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Autores principales: Fuentes,Ramón, Oporto Venegas,Gonzalo, Olate,Sergio, Rojas Rauco,Mariana, Borie,Eduardo
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2011
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000100047
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spelling oai:scielo:S0717-950220110001000472011-09-21Histological Evaluation of Bone Regeneration Means Freeze Dried Bone Allograft (FDBA) in Post Exodontia SocketsFuentes,RamónOporto Venegas,GonzaloOlate,SergioRojas Rauco,MarianaBorie,Eduardo Bone regeneration Biomaterials FDBA Socket Within oral rehabilitation alveolar ridge preservation following extraction is important. This research study shows a histological, histochemical and histomorphometrical evaluation in two cases of post extraction ridge-socket preservation performed with FDBA. In two patients dental extraction procedures were performed and sockets were immediately filled with FDBA. Six months later a biopsy of grafted area was obtained and rehabilitated through dental implant. Grafted bone samples were treated for histological and histochemical analysis. Bone tissue area was measured. Laboratory analysis of three samples showed inactive bone surfaces, neither osteoblasts nor osteoclasts were found, only osteocyte and osteogenous cells were observed. These findings do not mean that tissue is metabolically inactive, rather bone genesis develop from a tissue matrix with the potential to generate undifferentiated osteocytes, and a micro environment with proteins such as bone morphogenetic proteins (BPM). Inactive biomaterial particles were not observed. Samples showed 0% and 30% bone tissue respectively. Considering histological differences between this and other research studies, it is necessary to develop further investigation to increase knowledge of processes involved in bone regeneration as well as bone quality, considering the variability that could be seen in each patient.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.29 n.1 20112011-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000100047en10.4067/S0717-95022011000100047
institution Scielo Chile
collection Scielo Chile
language English
topic Bone regeneration
Biomaterials
FDBA
Socket
spellingShingle Bone regeneration
Biomaterials
FDBA
Socket
Fuentes,Ramón
Oporto Venegas,Gonzalo
Olate,Sergio
Rojas Rauco,Mariana
Borie,Eduardo
Histological Evaluation of Bone Regeneration Means Freeze Dried Bone Allograft (FDBA) in Post Exodontia Sockets
description Within oral rehabilitation alveolar ridge preservation following extraction is important. This research study shows a histological, histochemical and histomorphometrical evaluation in two cases of post extraction ridge-socket preservation performed with FDBA. In two patients dental extraction procedures were performed and sockets were immediately filled with FDBA. Six months later a biopsy of grafted area was obtained and rehabilitated through dental implant. Grafted bone samples were treated for histological and histochemical analysis. Bone tissue area was measured. Laboratory analysis of three samples showed inactive bone surfaces, neither osteoblasts nor osteoclasts were found, only osteocyte and osteogenous cells were observed. These findings do not mean that tissue is metabolically inactive, rather bone genesis develop from a tissue matrix with the potential to generate undifferentiated osteocytes, and a micro environment with proteins such as bone morphogenetic proteins (BPM). Inactive biomaterial particles were not observed. Samples showed 0% and 30% bone tissue respectively. Considering histological differences between this and other research studies, it is necessary to develop further investigation to increase knowledge of processes involved in bone regeneration as well as bone quality, considering the variability that could be seen in each patient.
author Fuentes,Ramón
Oporto Venegas,Gonzalo
Olate,Sergio
Rojas Rauco,Mariana
Borie,Eduardo
author_facet Fuentes,Ramón
Oporto Venegas,Gonzalo
Olate,Sergio
Rojas Rauco,Mariana
Borie,Eduardo
author_sort Fuentes,Ramón
title Histological Evaluation of Bone Regeneration Means Freeze Dried Bone Allograft (FDBA) in Post Exodontia Sockets
title_short Histological Evaluation of Bone Regeneration Means Freeze Dried Bone Allograft (FDBA) in Post Exodontia Sockets
title_full Histological Evaluation of Bone Regeneration Means Freeze Dried Bone Allograft (FDBA) in Post Exodontia Sockets
title_fullStr Histological Evaluation of Bone Regeneration Means Freeze Dried Bone Allograft (FDBA) in Post Exodontia Sockets
title_full_unstemmed Histological Evaluation of Bone Regeneration Means Freeze Dried Bone Allograft (FDBA) in Post Exodontia Sockets
title_sort histological evaluation of bone regeneration means freeze dried bone allograft (fdba) in post exodontia sockets
publisher Sociedad Chilena de Anatomía
publishDate 2011
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000100047
work_keys_str_mv AT fuentesramon histologicalevaluationofboneregenerationmeansfreezedriedboneallograftfdbainpostexodontiasockets
AT oportovenegasgonzalo histologicalevaluationofboneregenerationmeansfreezedriedboneallograftfdbainpostexodontiasockets
AT olatesergio histologicalevaluationofboneregenerationmeansfreezedriedboneallograftfdbainpostexodontiasockets
AT rojasraucomariana histologicalevaluationofboneregenerationmeansfreezedriedboneallograftfdbainpostexodontiasockets
AT borieeduardo histologicalevaluationofboneregenerationmeansfreezedriedboneallograftfdbainpostexodontiasockets
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