The Effects of Cadmium Chloride on the Oesophagus of Rats

Cadmium Chloride (CdC1) is a teratogen which is commonly used in industry. Although it is well known to cause toxicity in testes, kidney, heart and liver, few studies have been carried out in the digestive system. In the present study the effects of CdC1 on the esophagus of rats were investigated Wi...

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Autores principales: Deveci,E, Deveci,S
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2011
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Rat
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000300002
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spelling oai:scielo:S0717-950220110003000022012-06-11The Effects of Cadmium Chloride on the Oesophagus of RatsDeveci,EDeveci,S Cadmium cloride Oesephagus Rat Cadmium Chloride (CdC1) is a teratogen which is commonly used in industry. Although it is well known to cause toxicity in testes, kidney, heart and liver, few studies have been carried out in the digestive system. In the present study the effects of CdC1 on the esophagus of rats were investigated Wistar albino rats weighing 180 ­ 200 g were used. The animals were divided into two groups; one group was administered 2 mg/kg/day CdC1 intraperitoneally for one week. Esophagus was removed and placed in 10% formaline. Sections were stained with Hematoxylene-Eosine and observed under light microscopy. Hyperplasia in the epithelium, an increase in fibrotic cells under epithelium, hemorrhage in vessels, free floating erythrocytes were all observed following fetal exposure. In conclusion and most importantly, cadmium chloride was found to cause an increase in connective tissue in esophagus mucosa.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.29 n.3 20112011-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000300002en10.4067/S0717-95022011000300002
institution Scielo Chile
collection Scielo Chile
language English
topic Cadmium cloride
Oesephagus
Rat
spellingShingle Cadmium cloride
Oesephagus
Rat
Deveci,E
Deveci,S
The Effects of Cadmium Chloride on the Oesophagus of Rats
description Cadmium Chloride (CdC1) is a teratogen which is commonly used in industry. Although it is well known to cause toxicity in testes, kidney, heart and liver, few studies have been carried out in the digestive system. In the present study the effects of CdC1 on the esophagus of rats were investigated Wistar albino rats weighing 180 ­ 200 g were used. The animals were divided into two groups; one group was administered 2 mg/kg/day CdC1 intraperitoneally for one week. Esophagus was removed and placed in 10% formaline. Sections were stained with Hematoxylene-Eosine and observed under light microscopy. Hyperplasia in the epithelium, an increase in fibrotic cells under epithelium, hemorrhage in vessels, free floating erythrocytes were all observed following fetal exposure. In conclusion and most importantly, cadmium chloride was found to cause an increase in connective tissue in esophagus mucosa.
author Deveci,E
Deveci,S
author_facet Deveci,E
Deveci,S
author_sort Deveci,E
title The Effects of Cadmium Chloride on the Oesophagus of Rats
title_short The Effects of Cadmium Chloride on the Oesophagus of Rats
title_full The Effects of Cadmium Chloride on the Oesophagus of Rats
title_fullStr The Effects of Cadmium Chloride on the Oesophagus of Rats
title_full_unstemmed The Effects of Cadmium Chloride on the Oesophagus of Rats
title_sort effects of cadmium chloride on the oesophagus of rats
publisher Sociedad Chilena de Anatomía
publishDate 2011
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000300002
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