The Effects of Cadmium Chloride on the Oesophagus of Rats
Cadmium Chloride (CdC1) is a teratogen which is commonly used in industry. Although it is well known to cause toxicity in testes, kidney, heart and liver, few studies have been carried out in the digestive system. In the present study the effects of CdC1 on the esophagus of rats were investigated Wi...
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Sociedad Chilena de Anatomía
2011
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oai:scielo:S0717-950220110003000022012-06-11The Effects of Cadmium Chloride on the Oesophagus of RatsDeveci,EDeveci,S Cadmium cloride Oesephagus Rat Cadmium Chloride (CdC1) is a teratogen which is commonly used in industry. Although it is well known to cause toxicity in testes, kidney, heart and liver, few studies have been carried out in the digestive system. In the present study the effects of CdC1 on the esophagus of rats were investigated Wistar albino rats weighing 180 200 g were used. The animals were divided into two groups; one group was administered 2 mg/kg/day CdC1 intraperitoneally for one week. Esophagus was removed and placed in 10% formaline. Sections were stained with Hematoxylene-Eosine and observed under light microscopy. Hyperplasia in the epithelium, an increase in fibrotic cells under epithelium, hemorrhage in vessels, free floating erythrocytes were all observed following fetal exposure. In conclusion and most importantly, cadmium chloride was found to cause an increase in connective tissue in esophagus mucosa.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.29 n.3 20112011-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000300002en10.4067/S0717-95022011000300002 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
English |
topic |
Cadmium cloride Oesephagus Rat |
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Cadmium cloride Oesephagus Rat Deveci,E Deveci,S The Effects of Cadmium Chloride on the Oesophagus of Rats |
description |
Cadmium Chloride (CdC1) is a teratogen which is commonly used in industry. Although it is well known to cause toxicity in testes, kidney, heart and liver, few studies have been carried out in the digestive system. In the present study the effects of CdC1 on the esophagus of rats were investigated Wistar albino rats weighing 180 200 g were used. The animals were divided into two groups; one group was administered 2 mg/kg/day CdC1 intraperitoneally for one week. Esophagus was removed and placed in 10% formaline. Sections were stained with Hematoxylene-Eosine and observed under light microscopy. Hyperplasia in the epithelium, an increase in fibrotic cells under epithelium, hemorrhage in vessels, free floating erythrocytes were all observed following fetal exposure. In conclusion and most importantly, cadmium chloride was found to cause an increase in connective tissue in esophagus mucosa. |
author |
Deveci,E Deveci,S |
author_facet |
Deveci,E Deveci,S |
author_sort |
Deveci,E |
title |
The Effects of Cadmium Chloride on the Oesophagus of Rats |
title_short |
The Effects of Cadmium Chloride on the Oesophagus of Rats |
title_full |
The Effects of Cadmium Chloride on the Oesophagus of Rats |
title_fullStr |
The Effects of Cadmium Chloride on the Oesophagus of Rats |
title_full_unstemmed |
The Effects of Cadmium Chloride on the Oesophagus of Rats |
title_sort |
effects of cadmium chloride on the oesophagus of rats |
publisher |
Sociedad Chilena de Anatomía |
publishDate |
2011 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000300002 |
work_keys_str_mv |
AT devecie theeffectsofcadmiumchlorideontheoesophagusofrats AT devecis theeffectsofcadmiumchlorideontheoesophagusofrats AT devecie effectsofcadmiumchlorideontheoesophagusofrats AT devecis effectsofcadmiumchlorideontheoesophagusofrats |
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1718444737410629632 |