Immunohistochemical Fiber Type Profile in the Human Vocal Muscle

The vocal muscle is a striated muscle with important functions in the emission of laryngeal sound and physiology of the voice. Therefore the knowledge of its constitution is the basis for the prevention and management of voice disorders. We used 10 samples from the middle third of vocal muscles obta...

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Autores principales:	López,María José, Zárate,Michael, Cantín,Mario, Zavando,Daniela, Suazo Galdames,Iván
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2011
Materias:	Voice Vocal cords Laryngeal muscles Myosin Type I Myosin Type II Immunohistochemistry
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400014
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spelling	oai:scielo:S0717-950220110004000142012-07-30Immunohistochemical Fiber Type Profile in the Human Vocal MuscleLópez,María JoséZárate,MichaelCantín,MarioZavando,DanielaSuazo Galdames,Iván Voice Vocal cords Laryngeal muscles Myosin Type I Myosin Type II Immunohistochemistry The vocal muscle is a striated muscle with important functions in the emission of laryngeal sound and physiology of the voice. Therefore the knowledge of its constitution is the basis for the prevention and management of voice disorders. We used 10 samples from the middle third of vocal muscles obtained from autopsies of 6 male and 4 female subjects aged between 36 and 71 years. The samples were analyzed with BA-F8 monoclonal antibody to slow type I fibers, and antimyosin HC monoclonal antibody and antimyosin fast clone MY-32 antibody for types IIA, IIB, IIX, and neonatal fibers. We determined the distribution of the muscle fiber types and morphometric characteristics, evaluating the differences by sex and age group. The human vocal muscle presented a heterogeneous formation with a predominance of type II fibers at 51.99%, while type I fibers reached 48.01%; this difference was significant (p <0.05). Comparing fiber subtypes IIA and IIX, there is a slight predominance of type IIX fibers, although this is not statistically significant (p>0.05). In conclusion, the human vocal muscle the fibers were predominantly type II fast.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.29 n.4 20112011-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400014en10.4067/S0717-95022011000400014
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Voice Vocal cords Laryngeal muscles Myosin Type I Myosin Type II Immunohistochemistry
spellingShingle	Voice Vocal cords Laryngeal muscles Myosin Type I Myosin Type II Immunohistochemistry López,María José Zárate,Michael Cantín,Mario Zavando,Daniela Suazo Galdames,Iván Immunohistochemical Fiber Type Profile in the Human Vocal Muscle
description	The vocal muscle is a striated muscle with important functions in the emission of laryngeal sound and physiology of the voice. Therefore the knowledge of its constitution is the basis for the prevention and management of voice disorders. We used 10 samples from the middle third of vocal muscles obtained from autopsies of 6 male and 4 female subjects aged between 36 and 71 years. The samples were analyzed with BA-F8 monoclonal antibody to slow type I fibers, and antimyosin HC monoclonal antibody and antimyosin fast clone MY-32 antibody for types IIA, IIB, IIX, and neonatal fibers. We determined the distribution of the muscle fiber types and morphometric characteristics, evaluating the differences by sex and age group. The human vocal muscle presented a heterogeneous formation with a predominance of type II fibers at 51.99%, while type I fibers reached 48.01%; this difference was significant (p <0.05). Comparing fiber subtypes IIA and IIX, there is a slight predominance of type IIX fibers, although this is not statistically significant (p>0.05). In conclusion, the human vocal muscle the fibers were predominantly type II fast.
author	López,María José Zárate,Michael Cantín,Mario Zavando,Daniela Suazo Galdames,Iván
author_facet	López,María José Zárate,Michael Cantín,Mario Zavando,Daniela Suazo Galdames,Iván
author_sort	López,María José
title	Immunohistochemical Fiber Type Profile in the Human Vocal Muscle
title_short	Immunohistochemical Fiber Type Profile in the Human Vocal Muscle
title_full	Immunohistochemical Fiber Type Profile in the Human Vocal Muscle
title_fullStr	Immunohistochemical Fiber Type Profile in the Human Vocal Muscle
title_full_unstemmed	Immunohistochemical Fiber Type Profile in the Human Vocal Muscle
title_sort	immunohistochemical fiber type profile in the human vocal muscle
publisher	Sociedad Chilena de Anatomía
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400014
work_keys_str_mv	AT lopezmariajose immunohistochemicalfibertypeprofileinthehumanvocalmuscle AT zaratemichael immunohistochemicalfibertypeprofileinthehumanvocalmuscle AT cantinmario immunohistochemicalfibertypeprofileinthehumanvocalmuscle AT zavandodaniela immunohistochemicalfibertypeprofileinthehumanvocalmuscle AT suazogaldamesivan immunohistochemicalfibertypeprofileinthehumanvocalmuscle
_version_	1718444752217571328

Immunohistochemical Fiber Type Profile in the Human Vocal Muscle

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