Cytoarchitectural Variations in the Ovary, Oviduct and Uterus Following Intra-Gastric Gavages of Abrus precatorius Linn in Albino Rats

In developing countries, herbal medicines have continued to remain significant and readily patronized. Numerous plants have been used historically to reduce fertility and modern scientific research has confirmed antifertility effect in some of the herbs tested. To investigate the effects of Abrus pr...

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Autores principales:	Okoko,Ini-Ibehe Essien, Yama,Oshiozokhai Eboetse
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2011
Materias:	Abrus precatorius Sprague-Dawley rat Ovaries Uteri Oviducts
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400057
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spelling	oai:scielo:S0717-950220110004000572012-07-30Cytoarchitectural Variations in the Ovary, Oviduct and Uterus Following Intra-Gastric Gavages of Abrus precatorius Linn in Albino RatsOkoko,Ini-Ibehe EssienYama,Oshiozokhai Eboetse Abrus precatorius Sprague-Dawley rat Ovaries Uteri Oviducts In developing countries, herbal medicines have continued to remain significant and readily patronized. Numerous plants have been used historically to reduce fertility and modern scientific research has confirmed antifertility effect in some of the herbs tested. To investigate the effects of Abrus precatorius (AP) on the histology of the ovary, oviduct and uterus of female Sprague-Dawley (S-D) rat. A total of 40, 68 week old 4-day cycling female S-D rats were used. They were divided into the treatment, control and reversibility groups. The treatment and reversibility groups were fed oral AP seed extract (50 mg/kg b.w) for 32 days. A fraction of the rats in reversibility group was treated with distilled water for another 32 days. The control group were used to compare events in the other groups. At the end of the experimental durations animals were sacrificed under light chloroform anesthesia. Their ovaries, uteri and oviducts harvested for microscopic studies. Comparing the control histological sections to the treated groups: the ovaries showed decreased size, large follicular distension and extensive stromal necrosis with compromised cellularity. The uterine tubes revealed appreciable mucosal reduction. The uteri exhibited reduction in the layer of endometrial thickness. On the other hand sections in reversal experimental rats were comparable to control. The rats treated with AP seed extract at dose 50 mg/kg b.w induced reversible alterations in ovaries, uterine and uteri in S-D.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.29 n.4 20112011-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400057en10.4067/S0717-95022011000400057
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Abrus precatorius Sprague-Dawley rat Ovaries Uteri Oviducts
spellingShingle	Abrus precatorius Sprague-Dawley rat Ovaries Uteri Oviducts Okoko,Ini-Ibehe Essien Yama,Oshiozokhai Eboetse Cytoarchitectural Variations in the Ovary, Oviduct and Uterus Following Intra-Gastric Gavages of Abrus precatorius Linn in Albino Rats
description	In developing countries, herbal medicines have continued to remain significant and readily patronized. Numerous plants have been used historically to reduce fertility and modern scientific research has confirmed antifertility effect in some of the herbs tested. To investigate the effects of Abrus precatorius (AP) on the histology of the ovary, oviduct and uterus of female Sprague-Dawley (S-D) rat. A total of 40, 68 week old 4-day cycling female S-D rats were used. They were divided into the treatment, control and reversibility groups. The treatment and reversibility groups were fed oral AP seed extract (50 mg/kg b.w) for 32 days. A fraction of the rats in reversibility group was treated with distilled water for another 32 days. The control group were used to compare events in the other groups. At the end of the experimental durations animals were sacrificed under light chloroform anesthesia. Their ovaries, uteri and oviducts harvested for microscopic studies. Comparing the control histological sections to the treated groups: the ovaries showed decreased size, large follicular distension and extensive stromal necrosis with compromised cellularity. The uterine tubes revealed appreciable mucosal reduction. The uteri exhibited reduction in the layer of endometrial thickness. On the other hand sections in reversal experimental rats were comparable to control. The rats treated with AP seed extract at dose 50 mg/kg b.w induced reversible alterations in ovaries, uterine and uteri in S-D.
author	Okoko,Ini-Ibehe Essien Yama,Oshiozokhai Eboetse
author_facet	Okoko,Ini-Ibehe Essien Yama,Oshiozokhai Eboetse
author_sort	Okoko,Ini-Ibehe Essien
title	Cytoarchitectural Variations in the Ovary, Oviduct and Uterus Following Intra-Gastric Gavages of Abrus precatorius Linn in Albino Rats
title_short	Cytoarchitectural Variations in the Ovary, Oviduct and Uterus Following Intra-Gastric Gavages of Abrus precatorius Linn in Albino Rats
title_full	Cytoarchitectural Variations in the Ovary, Oviduct and Uterus Following Intra-Gastric Gavages of Abrus precatorius Linn in Albino Rats
title_fullStr	Cytoarchitectural Variations in the Ovary, Oviduct and Uterus Following Intra-Gastric Gavages of Abrus precatorius Linn in Albino Rats
title_full_unstemmed	Cytoarchitectural Variations in the Ovary, Oviduct and Uterus Following Intra-Gastric Gavages of Abrus precatorius Linn in Albino Rats
title_sort	cytoarchitectural variations in the ovary, oviduct and uterus following intra-gastric gavages of abrus precatorius linn in albino rats
publisher	Sociedad Chilena de Anatomía
publishDate	2011
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400057
work_keys_str_mv	AT okokoiniibeheessien cytoarchitecturalvariationsintheovaryoviductanduterusfollowingintragastricgavagesofabrusprecatoriuslinninalbinorats AT yamaoshiozokhaieboetse cytoarchitecturalvariationsintheovaryoviductanduterusfollowingintragastricgavagesofabrusprecatoriuslinninalbinorats
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Cytoarchitectural Variations in the Ovary, Oviduct and Uterus Following Intra-Gastric Gavages of Abrus precatorius Linn in Albino Rats

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