Sexual Differences in the Diameter of Coronary Arteries in an Adult Sri Lankan Population

Coronary artery disease is a major cause of human mortality. It is stated that females have worse outcomes than men following myocardial infarction and coronary revascularization. Sexual differences in the coronary artery diameters have also been speculated as one of the reasons for the above outcom...

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Autores principales: Ilayperuma,I, Nanayakkara,B. G, Palahepitiya,K. N
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2011
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400063
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spelling oai:scielo:S0717-950220110004000632012-07-30Sexual Differences in the Diameter of Coronary Arteries in an Adult Sri Lankan PopulationIlayperuma,INanayakkara,B. GPalahepitiya,K. N Coronary artery Sri Lankan Sexual differences Coronary artery disease is a major cause of human mortality. It is stated that females have worse outcomes than men following myocardial infarction and coronary revascularization. Sexual differences in the coronary artery diameters have also been speculated as one of the reasons for the above outcome. However, because of possible confounding effects, such as the body size and heart weight, it is unclear if there is a true sex-specific effect on coronary arterial size. The present study was undertaken to investigate the sexual differences in the diameter of coronary arteries in a group of adult Sri Lankan population. The diameters of the coronary arteries and their branches were measured at predetermined sites in a total of one hundred and two apparently healthy hearts obtained from cadavers during routine gross anatomy dissections. All measurements were taken using a digital sliding caliper capable of measuring to the nearest 0.01mm. The mean coronary arterial diameters were significantly smaller in females than in males. These differences persisted even after the diameters of coronary arteries were corrected for heart weight and body surface areas. Precise knowledge of the expected normal coronary arterial diameter at a given anatomic location is the first step towards developing a quantitative estimate of the severity of the coronary artery disease. This study provides a reference data set for adult Sri Lankans against which to compare the diameters of coronary arteries in various pathological conditions.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.29 n.4 20112011-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400063en10.4067/S0717-95022011000400063
institution Scielo Chile
collection Scielo Chile
language English
topic Coronary artery
Sri Lankan
Sexual differences
spellingShingle Coronary artery
Sri Lankan
Sexual differences
Ilayperuma,I
Nanayakkara,B. G
Palahepitiya,K. N
Sexual Differences in the Diameter of Coronary Arteries in an Adult Sri Lankan Population
description Coronary artery disease is a major cause of human mortality. It is stated that females have worse outcomes than men following myocardial infarction and coronary revascularization. Sexual differences in the coronary artery diameters have also been speculated as one of the reasons for the above outcome. However, because of possible confounding effects, such as the body size and heart weight, it is unclear if there is a true sex-specific effect on coronary arterial size. The present study was undertaken to investigate the sexual differences in the diameter of coronary arteries in a group of adult Sri Lankan population. The diameters of the coronary arteries and their branches were measured at predetermined sites in a total of one hundred and two apparently healthy hearts obtained from cadavers during routine gross anatomy dissections. All measurements were taken using a digital sliding caliper capable of measuring to the nearest 0.01mm. The mean coronary arterial diameters were significantly smaller in females than in males. These differences persisted even after the diameters of coronary arteries were corrected for heart weight and body surface areas. Precise knowledge of the expected normal coronary arterial diameter at a given anatomic location is the first step towards developing a quantitative estimate of the severity of the coronary artery disease. This study provides a reference data set for adult Sri Lankans against which to compare the diameters of coronary arteries in various pathological conditions.
author Ilayperuma,I
Nanayakkara,B. G
Palahepitiya,K. N
author_facet Ilayperuma,I
Nanayakkara,B. G
Palahepitiya,K. N
author_sort Ilayperuma,I
title Sexual Differences in the Diameter of Coronary Arteries in an Adult Sri Lankan Population
title_short Sexual Differences in the Diameter of Coronary Arteries in an Adult Sri Lankan Population
title_full Sexual Differences in the Diameter of Coronary Arteries in an Adult Sri Lankan Population
title_fullStr Sexual Differences in the Diameter of Coronary Arteries in an Adult Sri Lankan Population
title_full_unstemmed Sexual Differences in the Diameter of Coronary Arteries in an Adult Sri Lankan Population
title_sort sexual differences in the diameter of coronary arteries in an adult sri lankan population
publisher Sociedad Chilena de Anatomía
publishDate 2011
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022011000400063
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