Absorption Levels and Morphological Features of Fetal Organs in Wistar Rats Treated with Lead Acetate

Lead is one of the heavy metals most used in industry. Poisoning due to long-term lead exposure is known as saturnism, and is an occupational illness that has been known for many years. Lead is highly toxic and can compromise the structural and functional patterns of organs and systems. The aim of t...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Bomfim,Kátia Michelle dos Anjos, Garcia,Carlos Alexandre Borges, Reis,Francisco Prado, Palmeira,José Arnaldo Vasconcelos, Scher,Ricardo, de Lucca Júnior,Waldecy, Aragão,José Adeval, Vasconcelos,Francis Lima, Albuquerque Júnior,Ricardo Luiz Cavalcanti, Feitosa,Vera Lúcia Corrêa
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2012
Materias:	Lead acetate Fetuses Lung Kidney
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100021
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0717-95022012000100021
record_format	dspace
spelling	oai:scielo:S0717-950220120001000212012-06-08Absorption Levels and Morphological Features of Fetal Organs in Wistar Rats Treated with Lead AcetateBomfim,Kátia Michelle dos AnjosGarcia,Carlos Alexandre BorgesReis,Francisco PradoPalmeira,José Arnaldo VasconcelosScher,Ricardode Lucca Júnior,WaldecyAragão,José AdevalVasconcelos,Francis LimaAlbuquerque Júnior,Ricardo Luiz CavalcantiFeitosa,Vera Lúcia Corrêa Lead acetate Fetuses Lung Kidney Lead is one of the heavy metals most used in industry. Poisoning due to long-term lead exposure is known as saturnism, and is an occupational illness that has been known for many years. Lead is highly toxic and can compromise the structural and functional patterns of organs and systems. The aim of this study was to examine the lungs and kidneys of fetuses from female Wistar rats exposed to lead acetate. In this study, the lungs and kidneys of 20 fetuses from female rats that had previously been treated with lead acetate were dissected, fixed, embedded in paraffin and stained with hematoxylin and eosin. Macroscopic changes to the shape, color and consistency of organs from fetuses treated with this heavy metal were observed, in comparison with organs from control fetuses. Microscopic lesions characterized by vascular sclerosis, cell atrophy or hyperplasia, progressive interstitial fibrosis, inclusion bodies containing lead acetate and glomerular sclerosis were found in the kidneys. The lesions found in the lungs consisted of destructuring of the parenchyma, impregnation with lead acetate, formation of fibrosis, extravasation of vascular fluids, reduction of the alveolar spaces and formation of alveolar edema. These changes were correlated with the level of lead acetate absorption, as determined using atomic spectrophotometry.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.30 n.1 20122012-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100021en10.4067/S0717-95022012000100021
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Lead acetate Fetuses Lung Kidney
spellingShingle	Lead acetate Fetuses Lung Kidney Bomfim,Kátia Michelle dos Anjos Garcia,Carlos Alexandre Borges Reis,Francisco Prado Palmeira,José Arnaldo Vasconcelos Scher,Ricardo de Lucca Júnior,Waldecy Aragão,José Adeval Vasconcelos,Francis Lima Albuquerque Júnior,Ricardo Luiz Cavalcanti Feitosa,Vera Lúcia Corrêa Absorption Levels and Morphological Features of Fetal Organs in Wistar Rats Treated with Lead Acetate
description	Lead is one of the heavy metals most used in industry. Poisoning due to long-term lead exposure is known as saturnism, and is an occupational illness that has been known for many years. Lead is highly toxic and can compromise the structural and functional patterns of organs and systems. The aim of this study was to examine the lungs and kidneys of fetuses from female Wistar rats exposed to lead acetate. In this study, the lungs and kidneys of 20 fetuses from female rats that had previously been treated with lead acetate were dissected, fixed, embedded in paraffin and stained with hematoxylin and eosin. Macroscopic changes to the shape, color and consistency of organs from fetuses treated with this heavy metal were observed, in comparison with organs from control fetuses. Microscopic lesions characterized by vascular sclerosis, cell atrophy or hyperplasia, progressive interstitial fibrosis, inclusion bodies containing lead acetate and glomerular sclerosis were found in the kidneys. The lesions found in the lungs consisted of destructuring of the parenchyma, impregnation with lead acetate, formation of fibrosis, extravasation of vascular fluids, reduction of the alveolar spaces and formation of alveolar edema. These changes were correlated with the level of lead acetate absorption, as determined using atomic spectrophotometry.
author	Bomfim,Kátia Michelle dos Anjos Garcia,Carlos Alexandre Borges Reis,Francisco Prado Palmeira,José Arnaldo Vasconcelos Scher,Ricardo de Lucca Júnior,Waldecy Aragão,José Adeval Vasconcelos,Francis Lima Albuquerque Júnior,Ricardo Luiz Cavalcanti Feitosa,Vera Lúcia Corrêa
author_facet	Bomfim,Kátia Michelle dos Anjos Garcia,Carlos Alexandre Borges Reis,Francisco Prado Palmeira,José Arnaldo Vasconcelos Scher,Ricardo de Lucca Júnior,Waldecy Aragão,José Adeval Vasconcelos,Francis Lima Albuquerque Júnior,Ricardo Luiz Cavalcanti Feitosa,Vera Lúcia Corrêa
author_sort	Bomfim,Kátia Michelle dos Anjos
title	Absorption Levels and Morphological Features of Fetal Organs in Wistar Rats Treated with Lead Acetate
title_short	Absorption Levels and Morphological Features of Fetal Organs in Wistar Rats Treated with Lead Acetate
title_full	Absorption Levels and Morphological Features of Fetal Organs in Wistar Rats Treated with Lead Acetate
title_fullStr	Absorption Levels and Morphological Features of Fetal Organs in Wistar Rats Treated with Lead Acetate
title_full_unstemmed	Absorption Levels and Morphological Features of Fetal Organs in Wistar Rats Treated with Lead Acetate
title_sort	absorption levels and morphological features of fetal organs in wistar rats treated with lead acetate
publisher	Sociedad Chilena de Anatomía
publishDate	2012
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000100021
work_keys_str_mv	AT bomfimkatiamichelledosanjos absorptionlevelsandmorphologicalfeaturesoffetalorgansinwistarratstreatedwithleadacetate AT garciacarlosalexandreborges absorptionlevelsandmorphologicalfeaturesoffetalorgansinwistarratstreatedwithleadacetate AT reisfranciscoprado absorptionlevelsandmorphologicalfeaturesoffetalorgansinwistarratstreatedwithleadacetate AT palmeirajosearnaldovasconcelos absorptionlevelsandmorphologicalfeaturesoffetalorgansinwistarratstreatedwithleadacetate AT scherricardo absorptionlevelsandmorphologicalfeaturesoffetalorgansinwistarratstreatedwithleadacetate AT deluccajuniorwaldecy absorptionlevelsandmorphologicalfeaturesoffetalorgansinwistarratstreatedwithleadacetate AT aragaojoseadeval absorptionlevelsandmorphologicalfeaturesoffetalorgansinwistarratstreatedwithleadacetate AT vasconcelosfrancislima absorptionlevelsandmorphologicalfeaturesoffetalorgansinwistarratstreatedwithleadacetate AT albuquerquejuniorricardoluizcavalcanti absorptionlevelsandmorphologicalfeaturesoffetalorgansinwistarratstreatedwithleadacetate AT feitosaveraluciacorrea absorptionlevelsandmorphologicalfeaturesoffetalorgansinwistarratstreatedwithleadacetate
_version_	1718444765717987328

Absorption Levels and Morphological Features of Fetal Organs in Wistar Rats Treated with Lead Acetate

Ejemplares similares