Effects of Formaldehyde on Respiratory Mucosa in Rats

Formaldehyde inhalation, are known to be nasal mucosa irritating feature. This study we are examined the effects histopathologic of formaldehyde inhalation on rats by using light microscopy. 16 adult wistar albino rats were used in this study. 8 rats were in control group and 8 rats were in experime...

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Autores principales: Yorgancilar,E, Deveci,E, Deveci,S
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2012
Materias:
Rat
Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200026
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spelling oai:scielo:S0717-950220120002000262012-10-03Effects of Formaldehyde on Respiratory Mucosa in RatsYorgancilar,EDeveci,EDeveci,S Formaldehyde Rat Respiratory mucosa Formaldehyde inhalation, are known to be nasal mucosa irritating feature. This study we are examined the effects histopathologic of formaldehyde inhalation on rats by using light microscopy. 16 adult wistar albino rats were used in this study. 8 rats were in control group and 8 rats were in experiment group. Experiment group was exposed to 10 ppm formaldhyde 8hours/day,5days/week for 8 week. Nasal mucosa was removed and placed in 10% formaline. Sections were stained with Hematoxylene-Eosine and observed under light microscopy. The lining epithelium of respiratory mucosa showed a loss of ciliated cells with metaplasia of goblet cells and hyperplasia of squamous cells.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.30 n.2 20122012-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200026en10.4067/S0717-95022012000200026
institution Scielo Chile
collection Scielo Chile
language English
topic Formaldehyde
Rat
Respiratory mucosa
spellingShingle Formaldehyde
Rat
Respiratory mucosa
Yorgancilar,E
Deveci,E
Deveci,S
Effects of Formaldehyde on Respiratory Mucosa in Rats
description Formaldehyde inhalation, are known to be nasal mucosa irritating feature. This study we are examined the effects histopathologic of formaldehyde inhalation on rats by using light microscopy. 16 adult wistar albino rats were used in this study. 8 rats were in control group and 8 rats were in experiment group. Experiment group was exposed to 10 ppm formaldhyde 8hours/day,5days/week for 8 week. Nasal mucosa was removed and placed in 10% formaline. Sections were stained with Hematoxylene-Eosine and observed under light microscopy. The lining epithelium of respiratory mucosa showed a loss of ciliated cells with metaplasia of goblet cells and hyperplasia of squamous cells.
author Yorgancilar,E
Deveci,E
Deveci,S
author_facet Yorgancilar,E
Deveci,E
Deveci,S
author_sort Yorgancilar,E
title Effects of Formaldehyde on Respiratory Mucosa in Rats
title_short Effects of Formaldehyde on Respiratory Mucosa in Rats
title_full Effects of Formaldehyde on Respiratory Mucosa in Rats
title_fullStr Effects of Formaldehyde on Respiratory Mucosa in Rats
title_full_unstemmed Effects of Formaldehyde on Respiratory Mucosa in Rats
title_sort effects of formaldehyde on respiratory mucosa in rats
publisher Sociedad Chilena de Anatomía
publishDate 2012
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200026
work_keys_str_mv AT yorgancilare effectsofformaldehydeonrespiratorymucosainrats
AT devecie effectsofformaldehydeonrespiratorymucosainrats
AT devecis effectsofformaldehydeonrespiratorymucosainrats
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