Effects of Formaldehyde on Respiratory Mucosa in Rats

Formaldehyde inhalation, are known to be nasal mucosa irritating feature. This study we are examined the effects histopathologic of formaldehyde inhalation on rats by using light microscopy. 16 adult wistar albino rats were used in this study. 8 rats were in control group and 8 rats were in experime...

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Main Authors:	Yorgancilar,E, Deveci,E, Deveci,S
Language:	English
Published:	Sociedad Chilena de Anatomía 2012
Subjects:	Formaldehyde Rat Respiratory mucosa
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200026
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spelling	oai:scielo:S0717-950220120002000262012-10-03Effects of Formaldehyde on Respiratory Mucosa in RatsYorgancilar,EDeveci,EDeveci,S Formaldehyde Rat Respiratory mucosa Formaldehyde inhalation, are known to be nasal mucosa irritating feature. This study we are examined the effects histopathologic of formaldehyde inhalation on rats by using light microscopy. 16 adult wistar albino rats were used in this study. 8 rats were in control group and 8 rats were in experiment group. Experiment group was exposed to 10 ppm formaldhyde 8hours/day,5days/week for 8 week. Nasal mucosa was removed and placed in 10% formaline. Sections were stained with Hematoxylene-Eosine and observed under light microscopy. The lining epithelium of respiratory mucosa showed a loss of ciliated cells with metaplasia of goblet cells and hyperplasia of squamous cells.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.30 n.2 20122012-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200026en10.4067/S0717-95022012000200026
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Formaldehyde Rat Respiratory mucosa
spellingShingle	Formaldehyde Rat Respiratory mucosa Yorgancilar,E Deveci,E Deveci,S Effects of Formaldehyde on Respiratory Mucosa in Rats
description	Formaldehyde inhalation, are known to be nasal mucosa irritating feature. This study we are examined the effects histopathologic of formaldehyde inhalation on rats by using light microscopy. 16 adult wistar albino rats were used in this study. 8 rats were in control group and 8 rats were in experiment group. Experiment group was exposed to 10 ppm formaldhyde 8hours/day,5days/week for 8 week. Nasal mucosa was removed and placed in 10% formaline. Sections were stained with Hematoxylene-Eosine and observed under light microscopy. The lining epithelium of respiratory mucosa showed a loss of ciliated cells with metaplasia of goblet cells and hyperplasia of squamous cells.
author	Yorgancilar,E Deveci,E Deveci,S
author_facet	Yorgancilar,E Deveci,E Deveci,S
author_sort	Yorgancilar,E
title	Effects of Formaldehyde on Respiratory Mucosa in Rats
title_short	Effects of Formaldehyde on Respiratory Mucosa in Rats
title_full	Effects of Formaldehyde on Respiratory Mucosa in Rats
title_fullStr	Effects of Formaldehyde on Respiratory Mucosa in Rats
title_full_unstemmed	Effects of Formaldehyde on Respiratory Mucosa in Rats
title_sort	effects of formaldehyde on respiratory mucosa in rats
publisher	Sociedad Chilena de Anatomía
publishDate	2012
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000200026
work_keys_str_mv	AT yorgancilare effectsofformaldehydeonrespiratorymucosainrats AT devecie effectsofformaldehydeonrespiratorymucosainrats AT devecis effectsofformaldehydeonrespiratorymucosainrats
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Effects of Formaldehyde on Respiratory Mucosa in Rats

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