High Concentration of Reticular Fibers in Periurethral Region of the Prostatic Urethra from Patients with Benign Prostatic Hyperplasia as Revealed by Stereology

The goal of this investigation was to analyze and quantify changes of the reticular fibers in the prostatic urethra of patients with benign prostatic hyperplasia (BPH) and compare with a control group. Prostatic urethra tissue samples were obtained from ten patients (age range 65 to 79 years, mean 6...

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Autores principales: Manaia,Jorge H. M, Costa,Waldemar S, Sampaio,Francisco J. B, Figueiredo,Marcelo A, Cardoso,Gilberto P, Babinski,Marcio A
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2012
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000300065
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spelling oai:scielo:S0717-950220120003000652013-02-20High Concentration of Reticular Fibers in Periurethral Region of the Prostatic Urethra from Patients with Benign Prostatic Hyperplasia as Revealed by StereologyManaia,Jorge H. MCosta,Waldemar SSampaio,Francisco J. BFigueiredo,Marcelo ACardoso,Gilberto PBabinski,Marcio A Prostatic urethra Reticular fibers Stereology The goal of this investigation was to analyze and quantify changes of the reticular fibers in the prostatic urethra of patients with benign prostatic hyperplasia (BPH) and compare with a control group. Prostatic urethra tissue samples were obtained from ten patients (age range 65 to 79 years, mean 66) with clinical symptoms of bladder outlet obstruction who had undergone open prostatectomy. The ten control group samples (urethral tissue samples from the transitional zone) were collected from prostates obtained during autopsy of accidental death adults of less than 25 years. The Vv of the reticular fibers was determined with stereologic methods from 25 random fields per sample using the point-count method with a M-42 grid test system. The quantitative data were analyzed using the Kolmogorov-Smirnov and Mann-Whitney U tests. The Vv (mean±SD) in the control and BPH groups respectively were: 23.4± 1.8 and 30.3 ± 1.2 (0.001). BPH cause significant increase of reticular fibers in prostatic urethra.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.30 n.3 20122012-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000300065en10.4067/S0717-95022012000300065
institution Scielo Chile
collection Scielo Chile
language English
topic Prostatic urethra
Reticular fibers
Stereology
spellingShingle Prostatic urethra
Reticular fibers
Stereology
Manaia,Jorge H. M
Costa,Waldemar S
Sampaio,Francisco J. B
Figueiredo,Marcelo A
Cardoso,Gilberto P
Babinski,Marcio A
High Concentration of Reticular Fibers in Periurethral Region of the Prostatic Urethra from Patients with Benign Prostatic Hyperplasia as Revealed by Stereology
description The goal of this investigation was to analyze and quantify changes of the reticular fibers in the prostatic urethra of patients with benign prostatic hyperplasia (BPH) and compare with a control group. Prostatic urethra tissue samples were obtained from ten patients (age range 65 to 79 years, mean 66) with clinical symptoms of bladder outlet obstruction who had undergone open prostatectomy. The ten control group samples (urethral tissue samples from the transitional zone) were collected from prostates obtained during autopsy of accidental death adults of less than 25 years. The Vv of the reticular fibers was determined with stereologic methods from 25 random fields per sample using the point-count method with a M-42 grid test system. The quantitative data were analyzed using the Kolmogorov-Smirnov and Mann-Whitney U tests. The Vv (mean±SD) in the control and BPH groups respectively were: 23.4± 1.8 and 30.3 ± 1.2 (0.001). BPH cause significant increase of reticular fibers in prostatic urethra.
author Manaia,Jorge H. M
Costa,Waldemar S
Sampaio,Francisco J. B
Figueiredo,Marcelo A
Cardoso,Gilberto P
Babinski,Marcio A
author_facet Manaia,Jorge H. M
Costa,Waldemar S
Sampaio,Francisco J. B
Figueiredo,Marcelo A
Cardoso,Gilberto P
Babinski,Marcio A
author_sort Manaia,Jorge H. M
title High Concentration of Reticular Fibers in Periurethral Region of the Prostatic Urethra from Patients with Benign Prostatic Hyperplasia as Revealed by Stereology
title_short High Concentration of Reticular Fibers in Periurethral Region of the Prostatic Urethra from Patients with Benign Prostatic Hyperplasia as Revealed by Stereology
title_full High Concentration of Reticular Fibers in Periurethral Region of the Prostatic Urethra from Patients with Benign Prostatic Hyperplasia as Revealed by Stereology
title_fullStr High Concentration of Reticular Fibers in Periurethral Region of the Prostatic Urethra from Patients with Benign Prostatic Hyperplasia as Revealed by Stereology
title_full_unstemmed High Concentration of Reticular Fibers in Periurethral Region of the Prostatic Urethra from Patients with Benign Prostatic Hyperplasia as Revealed by Stereology
title_sort high concentration of reticular fibers in periurethral region of the prostatic urethra from patients with benign prostatic hyperplasia as revealed by stereology
publisher Sociedad Chilena de Anatomía
publishDate 2012
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022012000300065
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