Quick and Inexpensive Method to Elaborate Tissue Punches Useful in Paraffin Tissue Microarrays

The tissue microarrays (TMAs) were first called multitumor block. In 1998 was described the current technique, that uses an innovated sampling method for more than 1,000 cylindrical paraffin tissue core biopsies in a single paraffin block. TMAs are now considered as a useful powerful research tool i...

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Autores principales:	García-Garza,Rubén, Rodríguez-Vidales,Edgar Paolo, Soto-Domínguez,Adolfo
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2013
Materias:	Tissue microarrays Inexpensive Method
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000100007
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spelling	oai:scielo:S0717-950220130001000072014-09-09Quick and Inexpensive Method to Elaborate Tissue Punches Useful in Paraffin Tissue MicroarraysGarcía-Garza,RubénRodríguez-Vidales,Edgar PaoloSoto-Domínguez,Adolfo Tissue microarrays Inexpensive Method The tissue microarrays (TMAs) were first called multitumor block. In 1998 was described the current technique, that uses an innovated sampling method for more than 1,000 cylindrical paraffin tissue core biopsies in a single paraffin block. TMAs are now considered as a useful powerful research tool in Histology and Pathology laboratories, for the standardization of immunohistochemical techniques along with in situ hybridization. However, one disadvantage to its widespread use is the high cost of professional paraffin tissue punches, and the complexity in the development of homemade devices previously described in other studies. This study describes a step by step process to develop four different home-made devices made with materials that are common in hospitals and offices. These devices are useful in Histopathology laboratories to obtain paraffin blocks with until 360 samples of tissue, investing from two to fifteen dollars in the development of each device described.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.31 n.1 20132013-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000100007en10.4067/S0717-95022013000100007
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Tissue microarrays Inexpensive Method
spellingShingle	Tissue microarrays Inexpensive Method García-Garza,Rubén Rodríguez-Vidales,Edgar Paolo Soto-Domínguez,Adolfo Quick and Inexpensive Method to Elaborate Tissue Punches Useful in Paraffin Tissue Microarrays
description	The tissue microarrays (TMAs) were first called multitumor block. In 1998 was described the current technique, that uses an innovated sampling method for more than 1,000 cylindrical paraffin tissue core biopsies in a single paraffin block. TMAs are now considered as a useful powerful research tool in Histology and Pathology laboratories, for the standardization of immunohistochemical techniques along with in situ hybridization. However, one disadvantage to its widespread use is the high cost of professional paraffin tissue punches, and the complexity in the development of homemade devices previously described in other studies. This study describes a step by step process to develop four different home-made devices made with materials that are common in hospitals and offices. These devices are useful in Histopathology laboratories to obtain paraffin blocks with until 360 samples of tissue, investing from two to fifteen dollars in the development of each device described.
author	García-Garza,Rubén Rodríguez-Vidales,Edgar Paolo Soto-Domínguez,Adolfo
author_facet	García-Garza,Rubén Rodríguez-Vidales,Edgar Paolo Soto-Domínguez,Adolfo
author_sort	García-Garza,Rubén
title	Quick and Inexpensive Method to Elaborate Tissue Punches Useful in Paraffin Tissue Microarrays
title_short	Quick and Inexpensive Method to Elaborate Tissue Punches Useful in Paraffin Tissue Microarrays
title_full	Quick and Inexpensive Method to Elaborate Tissue Punches Useful in Paraffin Tissue Microarrays
title_fullStr	Quick and Inexpensive Method to Elaborate Tissue Punches Useful in Paraffin Tissue Microarrays
title_full_unstemmed	Quick and Inexpensive Method to Elaborate Tissue Punches Useful in Paraffin Tissue Microarrays
title_sort	quick and inexpensive method to elaborate tissue punches useful in paraffin tissue microarrays
publisher	Sociedad Chilena de Anatomía
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000100007
work_keys_str_mv	AT garciagarzaruben quickandinexpensivemethodtoelaboratetissuepunchesusefulinparaffintissuemicroarrays AT rodriguezvidalesedgarpaolo quickandinexpensivemethodtoelaboratetissuepunchesusefulinparaffintissuemicroarrays AT sotodominguezadolfo quickandinexpensivemethodtoelaboratetissuepunchesusefulinparaffintissuemicroarrays
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Quick and Inexpensive Method to Elaborate Tissue Punches Useful in Paraffin Tissue Microarrays

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