Comparison of Cerebellar Volume Between Subjects with Bilateral Congenital Blindness and Healthy Individuals

Cerebellum regulates motor control and physical coordination. It is known that when eye and hand need to be worked in combination, cerebellum is active and it provides coordination between eye and hand. Cerebellar cortex atrophy appears with dismetry and saccadic eye movement. If there is no stimula...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Kosif,Rengin, Sahin,Bünyamin, Gürel,Safiye
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2013
Materias:	Bilateral congenital blindness Cerebellum Volume
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000100039
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0717-95022013000100039
record_format	dspace
spelling	oai:scielo:S0717-950220130001000392014-09-09Comparison of Cerebellar Volume Between Subjects with Bilateral Congenital Blindness and Healthy IndividualsKosif,RenginSahin,BünyaminGürel,Safiye Bilateral congenital blindness Cerebellum Volume Cerebellum regulates motor control and physical coordination. It is known that when eye and hand need to be worked in combination, cerebellum is active and it provides coordination between eye and hand. Cerebellar cortex atrophy appears with dismetry and saccadic eye movement. If there is no stimulant related to vision, how cerebellum is adopted under this circumstance? In order to explore this, 27 male and 16 female volunteers with bilateral congenital blindness were compared with 35 male and 33 female healthy volunteers in this study. MR images of cross-sectional sequential cerebellum of volunteers with 1.5 mm thickness were realized in coronal plane. The surface area of apparent cerebellum seen in cross-sections was calculated by using Onis (Ver. 2.1) programme. Surface area data obtained by systematic randomized sampling were converted to volume by Cavalieri method. Cerebellar volume of bilateral congenital blind male was 128.15 ± 11.11 cm3, and cerebellar volume of bilateral congenital blind female was 118.60 ±10.73 cm3. Cerebellar volume for healthy men and women were 132.89 ± 12.51 cm3 and 125.97 ± 10.78 cm3, respectively. It was revealed that cerebellar volume for bilateral congenital blind men was smaller than that of healthy men, but this difference was not significant. On the other hand cerebellar volume of bilateral congenital blind women was significantly smaller than that of healthy women (p<0.05). No asymmetry was detected between right and left side of cerebellum in both bilateral congenital blind and healthy subjects.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.31 n.1 20132013-03-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000100039en10.4067/S0717-95022013000100039
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Bilateral congenital blindness Cerebellum Volume
spellingShingle	Bilateral congenital blindness Cerebellum Volume Kosif,Rengin Sahin,Bünyamin Gürel,Safiye Comparison of Cerebellar Volume Between Subjects with Bilateral Congenital Blindness and Healthy Individuals
description	Cerebellum regulates motor control and physical coordination. It is known that when eye and hand need to be worked in combination, cerebellum is active and it provides coordination between eye and hand. Cerebellar cortex atrophy appears with dismetry and saccadic eye movement. If there is no stimulant related to vision, how cerebellum is adopted under this circumstance? In order to explore this, 27 male and 16 female volunteers with bilateral congenital blindness were compared with 35 male and 33 female healthy volunteers in this study. MR images of cross-sectional sequential cerebellum of volunteers with 1.5 mm thickness were realized in coronal plane. The surface area of apparent cerebellum seen in cross-sections was calculated by using Onis (Ver. 2.1) programme. Surface area data obtained by systematic randomized sampling were converted to volume by Cavalieri method. Cerebellar volume of bilateral congenital blind male was 128.15 ± 11.11 cm3, and cerebellar volume of bilateral congenital blind female was 118.60 ±10.73 cm3. Cerebellar volume for healthy men and women were 132.89 ± 12.51 cm3 and 125.97 ± 10.78 cm3, respectively. It was revealed that cerebellar volume for bilateral congenital blind men was smaller than that of healthy men, but this difference was not significant. On the other hand cerebellar volume of bilateral congenital blind women was significantly smaller than that of healthy women (p<0.05). No asymmetry was detected between right and left side of cerebellum in both bilateral congenital blind and healthy subjects.
author	Kosif,Rengin Sahin,Bünyamin Gürel,Safiye
author_facet	Kosif,Rengin Sahin,Bünyamin Gürel,Safiye
author_sort	Kosif,Rengin
title	Comparison of Cerebellar Volume Between Subjects with Bilateral Congenital Blindness and Healthy Individuals
title_short	Comparison of Cerebellar Volume Between Subjects with Bilateral Congenital Blindness and Healthy Individuals
title_full	Comparison of Cerebellar Volume Between Subjects with Bilateral Congenital Blindness and Healthy Individuals
title_fullStr	Comparison of Cerebellar Volume Between Subjects with Bilateral Congenital Blindness and Healthy Individuals
title_full_unstemmed	Comparison of Cerebellar Volume Between Subjects with Bilateral Congenital Blindness and Healthy Individuals
title_sort	comparison of cerebellar volume between subjects with bilateral congenital blindness and healthy individuals
publisher	Sociedad Chilena de Anatomía
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000100039
work_keys_str_mv	AT kosifrengin comparisonofcerebellarvolumebetweensubjectswithbilateralcongenitalblindnessandhealthyindividuals AT sahinbunyamin comparisonofcerebellarvolumebetweensubjectswithbilateralcongenitalblindnessandhealthyindividuals AT gurelsafiye comparisonofcerebellarvolumebetweensubjectswithbilateralcongenitalblindnessandhealthyindividuals
_version_	1718444815737159680

Comparison of Cerebellar Volume Between Subjects with Bilateral Congenital Blindness and Healthy Individuals

Ejemplares similares