Histomorphometry of Preterm and Term Human Placentas

The intra-uterine existence of foetus is dependent on placenta, a major organ of nutrition and homeostasis.The present study was carried out to compare morphometric and histological changes in preterm and term human placentas. Eighty placentas collected from Department of Obstetrics and Gynecology,...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Zaidi,M. Tariq, Arshad,Mohd, Vasenwala,S. M, Faruqi,Nafis A, Khan,Aijaz A, Khan,Sumbul
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2013
Materias:	Placenta Syncytial knot Microvilli Hofbauer cells Syncytial bud
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200007
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0717-95022013000200007
record_format	dspace
spelling	oai:scielo:S0717-950220130002000072014-09-09Histomorphometry of Preterm and Term Human PlacentasZaidi,M. TariqArshad,MohdVasenwala,S. MFaruqi,Nafis AKhan,Aijaz AKhan,Sumbul Placenta Syncytial knot Microvilli Hofbauer cells Syncytial bud The intra-uterine existence of foetus is dependent on placenta, a major organ of nutrition and homeostasis.The present study was carried out to compare morphometric and histological changes in preterm and term human placentas. Eighty placentas collected from Department of Obstetrics and Gynecology, JNMCH, AMU, Aligarh, were divided into group first of preterm placentas up to 36 weeks (n =30) and second group of full term placentas i.e. 37 to 40 weeks ( n = 50) respectively. The samples were fixed in 10% formol-saline solution. The gross morphological variables of placentas were studied. There was a significant increase in the placental weight, decidual area and umbilical cord diameter of term placenta as compared to that of the preterm ones. From each placenta whole thickness tissue blocks were taken and processed for paraffin sectioning. Five µ-thick sections were stained with Haematoxylin-eosin and Van Gieson stains and processed for light microscopy. A total of 200 villi were studied in each sample under high power field and occurrence of different features was expressed as percentages for each parameter. The appearance of microvilli and syncytial bud on the syncytium were almost absent in the villi of term placentas. It was concluded that with increasing gestational age there was a gradual increase in the number of capillaries in villi from preterm to term placenta.There was a significant increase in syncytial knot count, fibrinoid necrosis, vasculosyncytial membrane and decrease in the percentage of villi showing cytotrophoblastic cells and number of Hofbauer cells in term group as compared to preterm group.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.31 n.2 20132013-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200007en10.4067/S0717-95022013000200007
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Placenta Syncytial knot Microvilli Hofbauer cells Syncytial bud
spellingShingle	Placenta Syncytial knot Microvilli Hofbauer cells Syncytial bud Zaidi,M. Tariq Arshad,Mohd Vasenwala,S. M Faruqi,Nafis A Khan,Aijaz A Khan,Sumbul Histomorphometry of Preterm and Term Human Placentas
description	The intra-uterine existence of foetus is dependent on placenta, a major organ of nutrition and homeostasis.The present study was carried out to compare morphometric and histological changes in preterm and term human placentas. Eighty placentas collected from Department of Obstetrics and Gynecology, JNMCH, AMU, Aligarh, were divided into group first of preterm placentas up to 36 weeks (n =30) and second group of full term placentas i.e. 37 to 40 weeks ( n = 50) respectively. The samples were fixed in 10% formol-saline solution. The gross morphological variables of placentas were studied. There was a significant increase in the placental weight, decidual area and umbilical cord diameter of term placenta as compared to that of the preterm ones. From each placenta whole thickness tissue blocks were taken and processed for paraffin sectioning. Five µ-thick sections were stained with Haematoxylin-eosin and Van Gieson stains and processed for light microscopy. A total of 200 villi were studied in each sample under high power field and occurrence of different features was expressed as percentages for each parameter. The appearance of microvilli and syncytial bud on the syncytium were almost absent in the villi of term placentas. It was concluded that with increasing gestational age there was a gradual increase in the number of capillaries in villi from preterm to term placenta.There was a significant increase in syncytial knot count, fibrinoid necrosis, vasculosyncytial membrane and decrease in the percentage of villi showing cytotrophoblastic cells and number of Hofbauer cells in term group as compared to preterm group.
author	Zaidi,M. Tariq Arshad,Mohd Vasenwala,S. M Faruqi,Nafis A Khan,Aijaz A Khan,Sumbul
author_facet	Zaidi,M. Tariq Arshad,Mohd Vasenwala,S. M Faruqi,Nafis A Khan,Aijaz A Khan,Sumbul
author_sort	Zaidi,M. Tariq
title	Histomorphometry of Preterm and Term Human Placentas
title_short	Histomorphometry of Preterm and Term Human Placentas
title_full	Histomorphometry of Preterm and Term Human Placentas
title_fullStr	Histomorphometry of Preterm and Term Human Placentas
title_full_unstemmed	Histomorphometry of Preterm and Term Human Placentas
title_sort	histomorphometry of preterm and term human placentas
publisher	Sociedad Chilena de Anatomía
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200007
work_keys_str_mv	AT zaidimtariq histomorphometryofpretermandtermhumanplacentas AT arshadmohd histomorphometryofpretermandtermhumanplacentas AT vasenwalasm histomorphometryofpretermandtermhumanplacentas AT faruqinafisa histomorphometryofpretermandtermhumanplacentas AT khanaijaza histomorphometryofpretermandtermhumanplacentas AT khansumbul histomorphometryofpretermandtermhumanplacentas
_version_	1718444819941949440

Histomorphometry of Preterm and Term Human Placentas

Ejemplares similares