Relation of Breast Cancer and Malathion Aerial Spraying in Arica, Chile

Breast cancer mortality has been increasing in Arica Chile where it has surpassed the national rates 11 times between 1990 and 2010. The city of Arica was sprayed with the organophosphrous pesticide malathion in order to control the Mediterranean fly 33 years ago. Moreover we have demonstrated that...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Cabello,Gertrudis, Valenzuela-Estrada,Mario, Siques,Patricia, Brito,Julio, Parra,Eduardo, Valdivia,Ursula, Lavin,Claudia, Manríquez,Alejandra, Ortega,Alejandro
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2013
Materias:	Pesticides Organophosphates Cholinesterase inhibitor Metastases Population health
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200048
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:scielo:S0717-95022013000200048
record_format	dspace
spelling	oai:scielo:S0717-950220130002000482014-09-09Relation of Breast Cancer and Malathion Aerial Spraying in Arica, ChileCabello,GertrudisValenzuela-Estrada,MarioSiques,PatriciaBrito,JulioParra,EduardoValdivia,UrsulaLavin,ClaudiaManríquez,AlejandraOrtega,Alejandro Pesticides Organophosphates Cholinesterase inhibitor Metastases Population health Breast cancer mortality has been increasing in Arica Chile where it has surpassed the national rates 11 times between 1990 and 2010. The city of Arica was sprayed with the organophosphrous pesticide malathion in order to control the Mediterranean fly 33 years ago. Moreover we have demonstrated that a malathion treatment induces the formation of breast carcinomas in Sprague Dowley female rats. The objective of this work was to find a relationship between malathion aerial spraying and the increased mortality rate due to breast cancer that has been observed in Arica in recent years. We extracted city data bases with all breast cancer cases diagnosed from 1995 to 2005 from the Dr. Juan Noe Crevani Hospital of Arica city and Ernesto Torres Hospital of Iquique. The number of patients was 100 in Arica and 58 in Iquique, nearby city that has never been sprayed with malathion which had a similar population than Arica in those years. The statistical analysis of the characteristics of the sample related to breast cancer risk showed that there is no significant difference between women from Arica and from Iquique. Nevertheless the patients with more times of exposure to malathion were 5.7-times more likely to be diagnosed with breast cancer (OR= 5.7; p<0.02). In addition, metastases were found in 30.5% of the malathion-exposed group and only in 16% in the group never exposed (p<0.05). This study suggests that the increase in the mortality rate due to breast cancer occurring in Arica has a significant correlation with the exposure to malathion sprayed over the city more than 30 years ago.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.31 n.2 20132013-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200048en10.4067/S0717-95022013000200048
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Pesticides Organophosphates Cholinesterase inhibitor Metastases Population health
spellingShingle	Pesticides Organophosphates Cholinesterase inhibitor Metastases Population health Cabello,Gertrudis Valenzuela-Estrada,Mario Siques,Patricia Brito,Julio Parra,Eduardo Valdivia,Ursula Lavin,Claudia Manríquez,Alejandra Ortega,Alejandro Relation of Breast Cancer and Malathion Aerial Spraying in Arica, Chile
description	Breast cancer mortality has been increasing in Arica Chile where it has surpassed the national rates 11 times between 1990 and 2010. The city of Arica was sprayed with the organophosphrous pesticide malathion in order to control the Mediterranean fly 33 years ago. Moreover we have demonstrated that a malathion treatment induces the formation of breast carcinomas in Sprague Dowley female rats. The objective of this work was to find a relationship between malathion aerial spraying and the increased mortality rate due to breast cancer that has been observed in Arica in recent years. We extracted city data bases with all breast cancer cases diagnosed from 1995 to 2005 from the Dr. Juan Noe Crevani Hospital of Arica city and Ernesto Torres Hospital of Iquique. The number of patients was 100 in Arica and 58 in Iquique, nearby city that has never been sprayed with malathion which had a similar population than Arica in those years. The statistical analysis of the characteristics of the sample related to breast cancer risk showed that there is no significant difference between women from Arica and from Iquique. Nevertheless the patients with more times of exposure to malathion were 5.7-times more likely to be diagnosed with breast cancer (OR= 5.7; p<0.02). In addition, metastases were found in 30.5% of the malathion-exposed group and only in 16% in the group never exposed (p<0.05). This study suggests that the increase in the mortality rate due to breast cancer occurring in Arica has a significant correlation with the exposure to malathion sprayed over the city more than 30 years ago.
author	Cabello,Gertrudis Valenzuela-Estrada,Mario Siques,Patricia Brito,Julio Parra,Eduardo Valdivia,Ursula Lavin,Claudia Manríquez,Alejandra Ortega,Alejandro
author_facet	Cabello,Gertrudis Valenzuela-Estrada,Mario Siques,Patricia Brito,Julio Parra,Eduardo Valdivia,Ursula Lavin,Claudia Manríquez,Alejandra Ortega,Alejandro
author_sort	Cabello,Gertrudis
title	Relation of Breast Cancer and Malathion Aerial Spraying in Arica, Chile
title_short	Relation of Breast Cancer and Malathion Aerial Spraying in Arica, Chile
title_full	Relation of Breast Cancer and Malathion Aerial Spraying in Arica, Chile
title_fullStr	Relation of Breast Cancer and Malathion Aerial Spraying in Arica, Chile
title_full_unstemmed	Relation of Breast Cancer and Malathion Aerial Spraying in Arica, Chile
title_sort	relation of breast cancer and malathion aerial spraying in arica, chile
publisher	Sociedad Chilena de Anatomía
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200048
work_keys_str_mv	AT cabellogertrudis relationofbreastcancerandmalathionaerialsprayinginaricachile AT valenzuelaestradamario relationofbreastcancerandmalathionaerialsprayinginaricachile AT siquespatricia relationofbreastcancerandmalathionaerialsprayinginaricachile AT britojulio relationofbreastcancerandmalathionaerialsprayinginaricachile AT parraeduardo relationofbreastcancerandmalathionaerialsprayinginaricachile AT valdiviaursula relationofbreastcancerandmalathionaerialsprayinginaricachile AT lavinclaudia relationofbreastcancerandmalathionaerialsprayinginaricachile AT manriquezalejandra relationofbreastcancerandmalathionaerialsprayinginaricachile AT ortegaalejandro relationofbreastcancerandmalathionaerialsprayinginaricachile
_version_	1718444827678343168

Relation of Breast Cancer and Malathion Aerial Spraying in Arica, Chile

Ejemplares similares