Morphometric and Anatomical Evaluation of the Heart of Wistar Rats

The use of animals in scientific research is not recent. The rat has been used in experiments since before Christ and, in the XIX century, with the intensification of the research reports, the use of this species increased considerably. Although this fact happens, the literature regarding the heart...

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Autores principales: de Carvalho,C. A. M, Thomazini,J. A
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2013
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200061
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spelling oai:scielo:S0717-950220130002000612014-09-09Morphometric and Anatomical Evaluation of the Heart of Wistar Ratsde Carvalho,C. A. MThomazini,J. A Heart Ventricle Atrium Rats The use of animals in scientific research is not recent. The rat has been used in experiments since before Christ and, in the XIX century, with the intensification of the research reports, the use of this species increased considerably. Although this fact happens, the literature regarding the heart of these animals is not very detailed and descriptive. The objective of this research is to study the macroscopic morphometric of several parameters that have not been described yet regarding the hearth of Wistar rats in different phases of their lives. Thirty-six adult male and female rats (Rattus norvegicus) weighing 150-770 g were randomly divided into 6 experimental groups: 6 animals of the group I male-weighting 150-249g (I-M); 6 animals of the group I female-weighting 150-249g (I-F); 6 animals of the group II male-weighting 250-350g (II-M); 6 animals of the group II-female­weighting (II-F); 6 animals of the group III-male weighting more than 35 g (III-M); 6 animals of the group III-female weighting more than 351g (III-F). The heart was then carefully dissected and removed from the chest. After this process, the heart had their weight measured on a precision scale HELMAC HM100, and for each front section of the heart were taken related measures through a semi-automatic image analysis of Kontron Build Analyse (Minimop). The percentage ratio between the relative heart weight to body weight was between 0.5 and 0.7% in the animals with body weight up to 650g, moreover, the wall thickness of the non-septal left ventricle was always lower for the females in all groups, while the interatrial septum have similar action in males and females and the thickness of the interventricular septum demonstrated to be similar to the wall thickness of the non-septal left ventricle.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.31 n.2 20132013-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200061en10.4067/S0717-95022013000200061
institution Scielo Chile
collection Scielo Chile
language English
topic Heart
Ventricle
Atrium
Rats
spellingShingle Heart
Ventricle
Atrium
Rats
de Carvalho,C. A. M
Thomazini,J. A
Morphometric and Anatomical Evaluation of the Heart of Wistar Rats
description The use of animals in scientific research is not recent. The rat has been used in experiments since before Christ and, in the XIX century, with the intensification of the research reports, the use of this species increased considerably. Although this fact happens, the literature regarding the heart of these animals is not very detailed and descriptive. The objective of this research is to study the macroscopic morphometric of several parameters that have not been described yet regarding the hearth of Wistar rats in different phases of their lives. Thirty-six adult male and female rats (Rattus norvegicus) weighing 150-770 g were randomly divided into 6 experimental groups: 6 animals of the group I male-weighting 150-249g (I-M); 6 animals of the group I female-weighting 150-249g (I-F); 6 animals of the group II male-weighting 250-350g (II-M); 6 animals of the group II-female­weighting (II-F); 6 animals of the group III-male weighting more than 35 g (III-M); 6 animals of the group III-female weighting more than 351g (III-F). The heart was then carefully dissected and removed from the chest. After this process, the heart had their weight measured on a precision scale HELMAC HM100, and for each front section of the heart were taken related measures through a semi-automatic image analysis of Kontron Build Analyse (Minimop). The percentage ratio between the relative heart weight to body weight was between 0.5 and 0.7% in the animals with body weight up to 650g, moreover, the wall thickness of the non-septal left ventricle was always lower for the females in all groups, while the interatrial septum have similar action in males and females and the thickness of the interventricular septum demonstrated to be similar to the wall thickness of the non-septal left ventricle.
author de Carvalho,C. A. M
Thomazini,J. A
author_facet de Carvalho,C. A. M
Thomazini,J. A
author_sort de Carvalho,C. A. M
title Morphometric and Anatomical Evaluation of the Heart of Wistar Rats
title_short Morphometric and Anatomical Evaluation of the Heart of Wistar Rats
title_full Morphometric and Anatomical Evaluation of the Heart of Wistar Rats
title_fullStr Morphometric and Anatomical Evaluation of the Heart of Wistar Rats
title_full_unstemmed Morphometric and Anatomical Evaluation of the Heart of Wistar Rats
title_sort morphometric and anatomical evaluation of the heart of wistar rats
publisher Sociedad Chilena de Anatomía
publishDate 2013
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200061
work_keys_str_mv AT decarvalhocam morphometricandanatomicalevaluationoftheheartofwistarrats
AT thomazinija morphometricandanatomicalevaluationoftheheartofwistarrats
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