The Effects of Vasectomy on Epididymal Morphology and Sperm Parameters in Adult Male Balb/c mice

Vasectomy is a common contraceptive procedure in men. The present study is aimed to explore the impact of vasectomy on epididymal morphology and sperm parameters in adult male Balb/c mice. Twenty adult (age: 8 weeks) male Balb/c mice, weighting 20-30 g were used in the experiments. They were divided...

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Autores principales:	Amini Mahabadi,Javad, Nikzad,Hossein, Taherian,Aliakbar, Mohammadi,Forouzan
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2013
Materias:	Vasectomy Epididymis Mice Sperm Motility
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000400032
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spelling	oai:scielo:S0717-950220130004000322014-02-18The Effects of Vasectomy on Epididymal Morphology and Sperm Parameters in Adult Male Balb/c miceAmini Mahabadi,JavadNikzad,HosseinTaherian,AliakbarMohammadi,Forouzan Vasectomy Epididymis Mice Sperm Motility Vasectomy is a common contraceptive procedure in men. The present study is aimed to explore the impact of vasectomy on epididymal morphology and sperm parameters in adult male Balb/c mice. Twenty adult (age: 8 weeks) male Balb/c mice, weighting 20-30 g were used in the experiments. They were divided into 2 groups (vasectomy and sham). The operations were performed under sodium pentobarbital (40 mg/kg body weight, IP) anesthesia via a lower mid-abdominal incision. The left epididymis caput was fixed for histological studies and the right one was used for sperm count and motility. Progressive fast and slow sperm motility were significantly decreased in the vasectomized compared to the sham operation group (P<0.05) and the number of immotile sperm in the vasectomized group was increased in comparison to control group. Sperm granuloma was seen in 60% of epididymis after vasectomy. Also, Histological study showed an increase in tubular lumen diameter, interstitial space and infiltration of immune cells in interstitial tissue in vasectomized group. Vasectomy increases histopathological changes in epididymis and decreases the motility of sperm developing a reduction in fertility rates.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.31 n.4 20132013-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000400032en10.4067/S0717-95022013000400032
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Vasectomy Epididymis Mice Sperm Motility
spellingShingle	Vasectomy Epididymis Mice Sperm Motility Amini Mahabadi,Javad Nikzad,Hossein Taherian,Aliakbar Mohammadi,Forouzan The Effects of Vasectomy on Epididymal Morphology and Sperm Parameters in Adult Male Balb/c mice
description	Vasectomy is a common contraceptive procedure in men. The present study is aimed to explore the impact of vasectomy on epididymal morphology and sperm parameters in adult male Balb/c mice. Twenty adult (age: 8 weeks) male Balb/c mice, weighting 20-30 g were used in the experiments. They were divided into 2 groups (vasectomy and sham). The operations were performed under sodium pentobarbital (40 mg/kg body weight, IP) anesthesia via a lower mid-abdominal incision. The left epididymis caput was fixed for histological studies and the right one was used for sperm count and motility. Progressive fast and slow sperm motility were significantly decreased in the vasectomized compared to the sham operation group (P<0.05) and the number of immotile sperm in the vasectomized group was increased in comparison to control group. Sperm granuloma was seen in 60% of epididymis after vasectomy. Also, Histological study showed an increase in tubular lumen diameter, interstitial space and infiltration of immune cells in interstitial tissue in vasectomized group. Vasectomy increases histopathological changes in epididymis and decreases the motility of sperm developing a reduction in fertility rates.
author	Amini Mahabadi,Javad Nikzad,Hossein Taherian,Aliakbar Mohammadi,Forouzan
author_facet	Amini Mahabadi,Javad Nikzad,Hossein Taherian,Aliakbar Mohammadi,Forouzan
author_sort	Amini Mahabadi,Javad
title	The Effects of Vasectomy on Epididymal Morphology and Sperm Parameters in Adult Male Balb/c mice
title_short	The Effects of Vasectomy on Epididymal Morphology and Sperm Parameters in Adult Male Balb/c mice
title_full	The Effects of Vasectomy on Epididymal Morphology and Sperm Parameters in Adult Male Balb/c mice
title_fullStr	The Effects of Vasectomy on Epididymal Morphology and Sperm Parameters in Adult Male Balb/c mice
title_full_unstemmed	The Effects of Vasectomy on Epididymal Morphology and Sperm Parameters in Adult Male Balb/c mice
title_sort	effects of vasectomy on epididymal morphology and sperm parameters in adult male balb/c mice
publisher	Sociedad Chilena de Anatomía
publishDate	2013
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000400032
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The Effects of Vasectomy on Epididymal Morphology and Sperm Parameters in Adult Male Balb/c mice

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