Moringa oleifera Impairs the Morphology and Functions of the Kidney in Adult Wistar Rats
We tested the hypothesis that Moringa oleifera impairs the morphology and functions of the kidney in rats. Twenty-four adult male Wistar rats were employed in the study. Rats of Control Group I received physiological saline while rats of Groups II IV received 250, 500 and 750 mg/kg bodyweight of m...
Guardado en:
| Autores principales: | , , , , , |
|---|---|
| Lenguaje: | English |
| Publicado: |
Sociedad Chilena de Anatomía
2014
|
| Materias: | |
| Acceso en línea: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000200016 |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:scielo:S0717-95022014000200016 |
|---|---|
| record_format |
dspace |
| spelling |
oai:scielo:S0717-950220140002000162015-11-16Moringa oleifera Impairs the Morphology and Functions of the Kidney in Adult Wistar RatsAkinlolu,Abdulazeez AdelajaGhazali,Olaide KamalAmeen,Oloduowo MubarakOyebanji,Seunayo ComfortOmotoso,Gabriel OlaiyaEnaibe,Bernard Ufuoma Moringa oleifera Toxicity profile Kidney We tested the hypothesis that Moringa oleifera impairs the morphology and functions of the kidney in rats. Twenty-four adult male Wistar rats were employed in the study. Rats of Control Group I received physiological saline while rats of Groups II IV received 250, 500 and 750 mg/kg bodyweight of methanolic extract of Moringa oleifera respectively for twenty one days. No behavioral anomalies were observed in rats of Groups I IV. Rats of Control Group I gained statistically significant increased bodyweight while rats of Groups II IV experienced non-significant decreased bodyweight during experimental procedure. (P0.05). No statistical significant differences (P0.05) were observed in the analyses of the relative weights of kidneys of rats of Groups I IV. Histological examinations showed normal cyto-architecture of the kidneys of rats of Group I while the Capsular spaces of the kidneys of rats of Groups II IV appeared wider than those of Group I. Statistical analyses showed significant higher levels (P0.05) of Alanine and Aspartate Transaminases, and serum urea in rats of Groups II IV in a non- dose-dependent manner when compared to rats of Group I. Our findings are consistent with the stated hypothesis.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.32 n.2 20142014-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000200016en10.4067/S0717-95022014000200016 |
| institution |
Scielo Chile |
| collection |
Scielo Chile |
| language |
English |
| topic |
Moringa oleifera Toxicity profile Kidney |
| spellingShingle |
Moringa oleifera Toxicity profile Kidney Akinlolu,Abdulazeez Adelaja Ghazali,Olaide Kamal Ameen,Oloduowo Mubarak Oyebanji,Seunayo Comfort Omotoso,Gabriel Olaiya Enaibe,Bernard Ufuoma Moringa oleifera Impairs the Morphology and Functions of the Kidney in Adult Wistar Rats |
| description |
We tested the hypothesis that Moringa oleifera impairs the morphology and functions of the kidney in rats. Twenty-four adult male Wistar rats were employed in the study. Rats of Control Group I received physiological saline while rats of Groups II IV received 250, 500 and 750 mg/kg bodyweight of methanolic extract of Moringa oleifera respectively for twenty one days. No behavioral anomalies were observed in rats of Groups I IV. Rats of Control Group I gained statistically significant increased bodyweight while rats of Groups II IV experienced non-significant decreased bodyweight during experimental procedure. (P0.05). No statistical significant differences (P0.05) were observed in the analyses of the relative weights of kidneys of rats of Groups I IV. Histological examinations showed normal cyto-architecture of the kidneys of rats of Group I while the Capsular spaces of the kidneys of rats of Groups II IV appeared wider than those of Group I. Statistical analyses showed significant higher levels (P0.05) of Alanine and Aspartate Transaminases, and serum urea in rats of Groups II IV in a non- dose-dependent manner when compared to rats of Group I. Our findings are consistent with the stated hypothesis. |
| author |
Akinlolu,Abdulazeez Adelaja Ghazali,Olaide Kamal Ameen,Oloduowo Mubarak Oyebanji,Seunayo Comfort Omotoso,Gabriel Olaiya Enaibe,Bernard Ufuoma |
| author_facet |
Akinlolu,Abdulazeez Adelaja Ghazali,Olaide Kamal Ameen,Oloduowo Mubarak Oyebanji,Seunayo Comfort Omotoso,Gabriel Olaiya Enaibe,Bernard Ufuoma |
| author_sort |
Akinlolu,Abdulazeez Adelaja |
| title |
Moringa oleifera Impairs the Morphology and Functions of the Kidney in Adult Wistar Rats |
| title_short |
Moringa oleifera Impairs the Morphology and Functions of the Kidney in Adult Wistar Rats |
| title_full |
Moringa oleifera Impairs the Morphology and Functions of the Kidney in Adult Wistar Rats |
| title_fullStr |
Moringa oleifera Impairs the Morphology and Functions of the Kidney in Adult Wistar Rats |
| title_full_unstemmed |
Moringa oleifera Impairs the Morphology and Functions of the Kidney in Adult Wistar Rats |
| title_sort |
moringa oleifera impairs the morphology and functions of the kidney in adult wistar rats |
| publisher |
Sociedad Chilena de Anatomía |
| publishDate |
2014 |
| url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000200016 |
| work_keys_str_mv |
AT akinloluabdulazeezadelaja moringaoleiferaimpairsthemorphologyandfunctionsofthekidneyinadultwistarrats AT ghazaliolaidekamal moringaoleiferaimpairsthemorphologyandfunctionsofthekidneyinadultwistarrats AT ameenoloduowomubarak moringaoleiferaimpairsthemorphologyandfunctionsofthekidneyinadultwistarrats AT oyebanjiseunayocomfort moringaoleiferaimpairsthemorphologyandfunctionsofthekidneyinadultwistarrats AT omotosogabrielolaiya moringaoleiferaimpairsthemorphologyandfunctionsofthekidneyinadultwistarrats AT enaibebernardufuoma moringaoleiferaimpairsthemorphologyandfunctionsofthekidneyinadultwistarrats |
| _version_ |
1718444868845436928 |