The Effect of Walnut on the Weight, Blood Glucose and Sex Hormones of Diabetic Male Rats

Diabetes leads to reproductive dysfunctions by producing free radicals. It seems that using walnut can be effective in the damage induced by diabetes. The aim of the present study was to evaluate the effects of walnut consumption on sex hormones in diabetic Wistar male rats induced by STZ (streptozo...

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Autores principales: Ghorbani,R, Mokhtari,T, Khazaei,M, Salahshoor,M. R, Jalili,C, Bakhtiari,M
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2014
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000300015
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spelling oai:scielo:S0717-950220140003000152015-11-16The Effect of Walnut on the Weight, Blood Glucose and Sex Hormones of Diabetic Male RatsGhorbani,RMokhtari,TKhazaei,MSalahshoor,M. RJalili,CBakhtiari,M Walnut Diabetes Weight Blood glucose Sex hormones Diabetes leads to reproductive dysfunctions by producing free radicals. It seems that using walnut can be effective in the damage induced by diabetes. The aim of the present study was to evaluate the effects of walnut consumption on sex hormones in diabetic Wistar male rats induced by STZ (streptozotocin). Diabetes animals were induced by STZ (60 mg/kg). Rats were randomly divided into 5 groups (n=6), including normal diet and healthy (Sham), Diabetic by normal diet (control) and diabetic by 6, 9 and 12% walnut in their diet (experimental groups), and were examined for 6 weeks. Body weight, blood glucose (3 times), and sex hormones (testosterone, FSH and LH) were measured. Overall, in terms of the mean index, there was a significant difference in the percentage of weight changes between the groups (p<0.001). Blood glucose (3 times) significantly increased in experimental and control groups in comparison with sham group (p<0.001). FSH concentration significantly decreased in control group (p<0.05) and testosterone hormone decreased in experimental and control groups compared to sham group (p<0.05). Oral administration of walnut seems to prevent severe weight loss in the experimental models of diabetic rats and exerts appropriate and useful changes in blood glucose level as well as positive effects on the secretion of sex hormones.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.32 n.3 20142014-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000300015en10.4067/S0717-95022014000300015
institution Scielo Chile
collection Scielo Chile
language English
topic Walnut
Diabetes
Weight
Blood glucose
Sex hormones
spellingShingle Walnut
Diabetes
Weight
Blood glucose
Sex hormones
Ghorbani,R
Mokhtari,T
Khazaei,M
Salahshoor,M. R
Jalili,C
Bakhtiari,M
The Effect of Walnut on the Weight, Blood Glucose and Sex Hormones of Diabetic Male Rats
description Diabetes leads to reproductive dysfunctions by producing free radicals. It seems that using walnut can be effective in the damage induced by diabetes. The aim of the present study was to evaluate the effects of walnut consumption on sex hormones in diabetic Wistar male rats induced by STZ (streptozotocin). Diabetes animals were induced by STZ (60 mg/kg). Rats were randomly divided into 5 groups (n=6), including normal diet and healthy (Sham), Diabetic by normal diet (control) and diabetic by 6, 9 and 12% walnut in their diet (experimental groups), and were examined for 6 weeks. Body weight, blood glucose (3 times), and sex hormones (testosterone, FSH and LH) were measured. Overall, in terms of the mean index, there was a significant difference in the percentage of weight changes between the groups (p<0.001). Blood glucose (3 times) significantly increased in experimental and control groups in comparison with sham group (p<0.001). FSH concentration significantly decreased in control group (p<0.05) and testosterone hormone decreased in experimental and control groups compared to sham group (p<0.05). Oral administration of walnut seems to prevent severe weight loss in the experimental models of diabetic rats and exerts appropriate and useful changes in blood glucose level as well as positive effects on the secretion of sex hormones.
author Ghorbani,R
Mokhtari,T
Khazaei,M
Salahshoor,M. R
Jalili,C
Bakhtiari,M
author_facet Ghorbani,R
Mokhtari,T
Khazaei,M
Salahshoor,M. R
Jalili,C
Bakhtiari,M
author_sort Ghorbani,R
title The Effect of Walnut on the Weight, Blood Glucose and Sex Hormones of Diabetic Male Rats
title_short The Effect of Walnut on the Weight, Blood Glucose and Sex Hormones of Diabetic Male Rats
title_full The Effect of Walnut on the Weight, Blood Glucose and Sex Hormones of Diabetic Male Rats
title_fullStr The Effect of Walnut on the Weight, Blood Glucose and Sex Hormones of Diabetic Male Rats
title_full_unstemmed The Effect of Walnut on the Weight, Blood Glucose and Sex Hormones of Diabetic Male Rats
title_sort effect of walnut on the weight, blood glucose and sex hormones of diabetic male rats
publisher Sociedad Chilena de Anatomía
publishDate 2014
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000300015
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