End-To-Side Loop Neurorrhaphy: Axonal Comparative Stereological Study

Accidents or diseases can affect the peripheral part of the nervous system, which raises clinical and surgical therapies, among others. In this context, the technique of end-to-side neurorrhaphy is a treatment option, yet its modification loop needs some additional efficacy studies. The purpose of t...

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Autores principales:	Boer,Nagib Pezati, Viterbo,Fausto, Faleiros,Humberto Regis, Batigalia,Fernando, Boer,Ana Luísa Ricci, Carvalho Jr,Altair Antonio
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2014
Materias:	Nerve Axon Stereology Neurorrhaphy
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000300032
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spelling	oai:scielo:S0717-950220140003000322015-11-16End-To-Side Loop Neurorrhaphy: Axonal Comparative Stereological StudyBoer,Nagib PezatiViterbo,FaustoFaleiros,Humberto RegisBatigalia,FernandoBoer,Ana Luísa RicciCarvalho Jr,Altair Antonio Nerve Axon Stereology Neurorrhaphy Accidents or diseases can affect the peripheral part of the nervous system, which raises clinical and surgical therapies, among others. In this context, the technique of end-to-side neurorrhaphy is a treatment option, yet its modification loop needs some additional efficacy studies. The purpose of this study was to compare, among rats, stereological results (axons volume density) after end-to-side neurorrhaphy and after end-to-side loop neurorrhaphy. Thirty Wistar rats were used, divided into six groups (five animals per group), consisting of two control groups (for the fibular and tibial nerves), two study groups for the fibular nerve (one with an end-to-side neurorrhaphy, and the other with an end-to-side loop neurorrhaphy) and two study groups for the tibial nerve (with an end-to-side neurorrhaphy and the other one with an end-to-side loop neurorrhaphy). After 180 days, all groups were sacrificed for axonal stereological analysis (volume density) in distal nerve stumps. There was significant maintenance of neuronal-axonal density in the distal stumps to neurorrhaphy (p<0.005) compared with the normal stumps. The end-to-side loop neurorrhaphy is a therapeutic option as suture technique after complete nerve section, in order to restore most of the axonal functional integrity.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.32 n.3 20142014-09-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000300032en10.4067/S0717-95022014000300032
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Nerve Axon Stereology Neurorrhaphy
spellingShingle	Nerve Axon Stereology Neurorrhaphy Boer,Nagib Pezati Viterbo,Fausto Faleiros,Humberto Regis Batigalia,Fernando Boer,Ana Luísa Ricci Carvalho Jr,Altair Antonio End-To-Side Loop Neurorrhaphy: Axonal Comparative Stereological Study
description	Accidents or diseases can affect the peripheral part of the nervous system, which raises clinical and surgical therapies, among others. In this context, the technique of end-to-side neurorrhaphy is a treatment option, yet its modification loop needs some additional efficacy studies. The purpose of this study was to compare, among rats, stereological results (axons volume density) after end-to-side neurorrhaphy and after end-to-side loop neurorrhaphy. Thirty Wistar rats were used, divided into six groups (five animals per group), consisting of two control groups (for the fibular and tibial nerves), two study groups for the fibular nerve (one with an end-to-side neurorrhaphy, and the other with an end-to-side loop neurorrhaphy) and two study groups for the tibial nerve (with an end-to-side neurorrhaphy and the other one with an end-to-side loop neurorrhaphy). After 180 days, all groups were sacrificed for axonal stereological analysis (volume density) in distal nerve stumps. There was significant maintenance of neuronal-axonal density in the distal stumps to neurorrhaphy (p<0.005) compared with the normal stumps. The end-to-side loop neurorrhaphy is a therapeutic option as suture technique after complete nerve section, in order to restore most of the axonal functional integrity.
author	Boer,Nagib Pezati Viterbo,Fausto Faleiros,Humberto Regis Batigalia,Fernando Boer,Ana Luísa Ricci Carvalho Jr,Altair Antonio
author_facet	Boer,Nagib Pezati Viterbo,Fausto Faleiros,Humberto Regis Batigalia,Fernando Boer,Ana Luísa Ricci Carvalho Jr,Altair Antonio
author_sort	Boer,Nagib Pezati
title	End-To-Side Loop Neurorrhaphy: Axonal Comparative Stereological Study
title_short	End-To-Side Loop Neurorrhaphy: Axonal Comparative Stereological Study
title_full	End-To-Side Loop Neurorrhaphy: Axonal Comparative Stereological Study
title_fullStr	End-To-Side Loop Neurorrhaphy: Axonal Comparative Stereological Study
title_full_unstemmed	End-To-Side Loop Neurorrhaphy: Axonal Comparative Stereological Study
title_sort	end-to-side loop neurorrhaphy: axonal comparative stereological study
publisher	Sociedad Chilena de Anatomía
publishDate	2014
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000300032
work_keys_str_mv	AT boernagibpezati endtosideloopneurorrhaphyaxonalcomparativestereologicalstudy AT viterbofausto endtosideloopneurorrhaphyaxonalcomparativestereologicalstudy AT faleiroshumbertoregis endtosideloopneurorrhaphyaxonalcomparativestereologicalstudy AT batigaliafernando endtosideloopneurorrhaphyaxonalcomparativestereologicalstudy AT boeranaluisaricci endtosideloopneurorrhaphyaxonalcomparativestereologicalstudy AT carvalhojraltairantonio endtosideloopneurorrhaphyaxonalcomparativestereologicalstudy
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End-To-Side Loop Neurorrhaphy: Axonal Comparative Stereological Study

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