Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180

Indigofera suffruticosa is a plant generally used to treat infectious and inflammatory processes. This work aims to evaluate the histopathological changes in the liver tissue of mice with Sarcoma 180 after subchronic treatment with aqueous extract obtained by infusion and maceration of Indigofera su...

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Autores principales: da Silva,Ivanise Brito, Lima,Izabela Rangel, Santana,Marllon Alex Nascimento, Leite,Roberta Maria Pereira, Leite,Sônia Pereira
Lenguaje:English
Publicado: Sociedad Chilena de Anatomía 2014
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Acceso en línea:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000400017
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spelling oai:scielo:S0717-950220140004000172015-11-16Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180da Silva,Ivanise BritoLima,Izabela RangelSantana,Marllon Alex NascimentoLeite,Roberta Maria PereiraLeite,Sônia Pereira Liver I. suffruticosa Histopathology Histomorphometry Sarcoma 180 Indigofera suffruticosa is a plant generally used to treat infectious and inflammatory processes. This work aims to evaluate the histopathological changes in the liver tissue of mice with Sarcoma 180 after subchronic treatment with aqueous extract obtained by infusion and maceration of Indigofera suffruticosa leaves. Male mice were divided into four groups of six animals: G1, G2 and G3 patients with Sarcoma 180 and Sarcoma 180 G4 without sarcoma. G1 and G2 were treated with infusion mashing respectively (50 mg/kg ip); G3 and G4 controls received saline (15 ml/kg ip). The histopathological and morphometric analysis of liver tissue after subchronic treatment with aqueous extracts by infusion and maceration of the groups G1, G2 and G4 were similar and showed no degraded areas or leukocyte infiltration compared to G3, which shows a marked destruction of liver architecture. The results showed that after subchronic treatment with the aqueous extract of leaves Indigofera Suffruticosa obtained by infusion and maceration, the hepatic architecture was preserved, suggesting its use as an alternative hepatoprotective agent.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.32 n.4 20142014-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000400017en10.4067/S0717-95022014000400017
institution Scielo Chile
collection Scielo Chile
language English
topic Liver
I. suffruticosa
Histopathology
Histomorphometry
Sarcoma 180
spellingShingle Liver
I. suffruticosa
Histopathology
Histomorphometry
Sarcoma 180
da Silva,Ivanise Brito
Lima,Izabela Rangel
Santana,Marllon Alex Nascimento
Leite,Roberta Maria Pereira
Leite,Sônia Pereira
Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180
description Indigofera suffruticosa is a plant generally used to treat infectious and inflammatory processes. This work aims to evaluate the histopathological changes in the liver tissue of mice with Sarcoma 180 after subchronic treatment with aqueous extract obtained by infusion and maceration of Indigofera suffruticosa leaves. Male mice were divided into four groups of six animals: G1, G2 and G3 patients with Sarcoma 180 and Sarcoma 180 G4 without sarcoma. G1 and G2 were treated with infusion mashing respectively (50 mg/kg ip); G3 and G4 controls received saline (15 ml/kg ip). The histopathological and morphometric analysis of liver tissue after subchronic treatment with aqueous extracts by infusion and maceration of the groups G1, G2 and G4 were similar and showed no degraded areas or leukocyte infiltration compared to G3, which shows a marked destruction of liver architecture. The results showed that after subchronic treatment with the aqueous extract of leaves Indigofera Suffruticosa obtained by infusion and maceration, the hepatic architecture was preserved, suggesting its use as an alternative hepatoprotective agent.
author da Silva,Ivanise Brito
Lima,Izabela Rangel
Santana,Marllon Alex Nascimento
Leite,Roberta Maria Pereira
Leite,Sônia Pereira
author_facet da Silva,Ivanise Brito
Lima,Izabela Rangel
Santana,Marllon Alex Nascimento
Leite,Roberta Maria Pereira
Leite,Sônia Pereira
author_sort da Silva,Ivanise Brito
title Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180
title_short Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180
title_full Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180
title_fullStr Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180
title_full_unstemmed Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180
title_sort indigofera suffruticosa mill (fabaceae): hepatic responses in mice bearing sarcoma 180
publisher Sociedad Chilena de Anatomía
publishDate 2014
url http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000400017
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AT leiterobertamariapereira indigoferasuffruticosamillfabaceaehepaticresponsesinmicebearingsarcoma180
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