Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180
Indigofera suffruticosa is a plant generally used to treat infectious and inflammatory processes. This work aims to evaluate the histopathological changes in the liver tissue of mice with Sarcoma 180 after subchronic treatment with aqueous extract obtained by infusion and maceration of Indigofera su...
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Sociedad Chilena de Anatomía
2014
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oai:scielo:S0717-950220140004000172015-11-16Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180da Silva,Ivanise BritoLima,Izabela RangelSantana,Marllon Alex NascimentoLeite,Roberta Maria PereiraLeite,Sônia Pereira Liver I. suffruticosa Histopathology Histomorphometry Sarcoma 180 Indigofera suffruticosa is a plant generally used to treat infectious and inflammatory processes. This work aims to evaluate the histopathological changes in the liver tissue of mice with Sarcoma 180 after subchronic treatment with aqueous extract obtained by infusion and maceration of Indigofera suffruticosa leaves. Male mice were divided into four groups of six animals: G1, G2 and G3 patients with Sarcoma 180 and Sarcoma 180 G4 without sarcoma. G1 and G2 were treated with infusion mashing respectively (50 mg/kg ip); G3 and G4 controls received saline (15 ml/kg ip). The histopathological and morphometric analysis of liver tissue after subchronic treatment with aqueous extracts by infusion and maceration of the groups G1, G2 and G4 were similar and showed no degraded areas or leukocyte infiltration compared to G3, which shows a marked destruction of liver architecture. The results showed that after subchronic treatment with the aqueous extract of leaves Indigofera Suffruticosa obtained by infusion and maceration, the hepatic architecture was preserved, suggesting its use as an alternative hepatoprotective agent.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.32 n.4 20142014-12-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000400017en10.4067/S0717-95022014000400017 |
institution |
Scielo Chile |
collection |
Scielo Chile |
language |
English |
topic |
Liver I. suffruticosa Histopathology Histomorphometry Sarcoma 180 |
spellingShingle |
Liver I. suffruticosa Histopathology Histomorphometry Sarcoma 180 da Silva,Ivanise Brito Lima,Izabela Rangel Santana,Marllon Alex Nascimento Leite,Roberta Maria Pereira Leite,Sônia Pereira Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180 |
description |
Indigofera suffruticosa is a plant generally used to treat infectious and inflammatory processes. This work aims to evaluate the histopathological changes in the liver tissue of mice with Sarcoma 180 after subchronic treatment with aqueous extract obtained by infusion and maceration of Indigofera suffruticosa leaves. Male mice were divided into four groups of six animals: G1, G2 and G3 patients with Sarcoma 180 and Sarcoma 180 G4 without sarcoma. G1 and G2 were treated with infusion mashing respectively (50 mg/kg ip); G3 and G4 controls received saline (15 ml/kg ip). The histopathological and morphometric analysis of liver tissue after subchronic treatment with aqueous extracts by infusion and maceration of the groups G1, G2 and G4 were similar and showed no degraded areas or leukocyte infiltration compared to G3, which shows a marked destruction of liver architecture. The results showed that after subchronic treatment with the aqueous extract of leaves Indigofera Suffruticosa obtained by infusion and maceration, the hepatic architecture was preserved, suggesting its use as an alternative hepatoprotective agent. |
author |
da Silva,Ivanise Brito Lima,Izabela Rangel Santana,Marllon Alex Nascimento Leite,Roberta Maria Pereira Leite,Sônia Pereira |
author_facet |
da Silva,Ivanise Brito Lima,Izabela Rangel Santana,Marllon Alex Nascimento Leite,Roberta Maria Pereira Leite,Sônia Pereira |
author_sort |
da Silva,Ivanise Brito |
title |
Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180 |
title_short |
Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180 |
title_full |
Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180 |
title_fullStr |
Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180 |
title_full_unstemmed |
Indigofera suffruticosa Mill (Fabaceae): Hepatic Responses in Mice Bearing Sarcoma 180 |
title_sort |
indigofera suffruticosa mill (fabaceae): hepatic responses in mice bearing sarcoma 180 |
publisher |
Sociedad Chilena de Anatomía |
publishDate |
2014 |
url |
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022014000400017 |
work_keys_str_mv |
AT dasilvaivanisebrito indigoferasuffruticosamillfabaceaehepaticresponsesinmicebearingsarcoma180 AT limaizabelarangel indigoferasuffruticosamillfabaceaehepaticresponsesinmicebearingsarcoma180 AT santanamarllonalexnascimento indigoferasuffruticosamillfabaceaehepaticresponsesinmicebearingsarcoma180 AT leiterobertamariapereira indigoferasuffruticosamillfabaceaehepaticresponsesinmicebearingsarcoma180 AT leitesoniapereira indigoferasuffruticosamillfabaceaehepaticresponsesinmicebearingsarcoma180 |
_version_ |
1718444891060568064 |