Morphometric Alterations Induced by the Toxicity of Variable Sizes of Silver Nanoparticles

Silver nanoprticles (SNPs) are invested in medical, industrial and environmental applications. Little if any, is known about the morphometric alterations induced by the toxicity of SNPs. The aim of the present work is to find out the effect of variable size of SNPs on different morphometric paramete...

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Autores principales:	Almansour,Mansour, Jarrar,Qais, Battah,Abdelkader, Jarrar,Bashir
Lenguaje:	English
Publicado:	Sociedad Chilena de Anatomía 2015
Materias:	Silver nanoparticles Morphology Toxicology Liver Kidney Spleen
Acceso en línea:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200022
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spelling	oai:scielo:S0717-950220150002000222015-08-13Morphometric Alterations Induced by the Toxicity of Variable Sizes of Silver NanoparticlesAlmansour,MansourJarrar,QaisBattah,AbdelkaderJarrar,Bashir Silver nanoparticles Morphology Toxicology Liver Kidney Spleen Silver nanoprticles (SNPs) are invested in medical, industrial and environmental applications. Little if any, is known about the morphometric alterations induced by the toxicity of SNPs. The aim of the present work is to find out the effect of variable size of SNPs on different morphometric parameters. Adult healthy male mice (BAL/C) were subjected to (10 nm, 20 nm, 40 nm 60 nm and 100 nm) SNPs for 35 days. Silver NPs caused non-significant decline on the average weight, significant decline in food consumption, increase in water intake, unilateral blindness, tanning fur color and cholestasis together with a decrease in the relative ratio of the liver, kidney and spleen weight to body weight. Mice subjected to 10 nm and 20 nm were more affected than mice receiving larger nanoparticles. These findings may indicate that SNPs could induce morphometric alterations that are size related wheresmaller SNPs have more impact than the larger ones.info:eu-repo/semantics/openAccessSociedad Chilena de AnatomíaInternational Journal of Morphology v.33 n.2 20152015-06-01text/htmlhttp://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200022en10.4067/S0717-95022015000200022
institution	Scielo Chile
collection	Scielo Chile
language	English
topic	Silver nanoparticles Morphology Toxicology Liver Kidney Spleen
spellingShingle	Silver nanoparticles Morphology Toxicology Liver Kidney Spleen Almansour,Mansour Jarrar,Qais Battah,Abdelkader Jarrar,Bashir Morphometric Alterations Induced by the Toxicity of Variable Sizes of Silver Nanoparticles
description	Silver nanoprticles (SNPs) are invested in medical, industrial and environmental applications. Little if any, is known about the morphometric alterations induced by the toxicity of SNPs. The aim of the present work is to find out the effect of variable size of SNPs on different morphometric parameters. Adult healthy male mice (BAL/C) were subjected to (10 nm, 20 nm, 40 nm 60 nm and 100 nm) SNPs for 35 days. Silver NPs caused non-significant decline on the average weight, significant decline in food consumption, increase in water intake, unilateral blindness, tanning fur color and cholestasis together with a decrease in the relative ratio of the liver, kidney and spleen weight to body weight. Mice subjected to 10 nm and 20 nm were more affected than mice receiving larger nanoparticles. These findings may indicate that SNPs could induce morphometric alterations that are size related wheresmaller SNPs have more impact than the larger ones.
author	Almansour,Mansour Jarrar,Qais Battah,Abdelkader Jarrar,Bashir
author_facet	Almansour,Mansour Jarrar,Qais Battah,Abdelkader Jarrar,Bashir
author_sort	Almansour,Mansour
title	Morphometric Alterations Induced by the Toxicity of Variable Sizes of Silver Nanoparticles
title_short	Morphometric Alterations Induced by the Toxicity of Variable Sizes of Silver Nanoparticles
title_full	Morphometric Alterations Induced by the Toxicity of Variable Sizes of Silver Nanoparticles
title_fullStr	Morphometric Alterations Induced by the Toxicity of Variable Sizes of Silver Nanoparticles
title_full_unstemmed	Morphometric Alterations Induced by the Toxicity of Variable Sizes of Silver Nanoparticles
title_sort	morphometric alterations induced by the toxicity of variable sizes of silver nanoparticles
publisher	Sociedad Chilena de Anatomía
publishDate	2015
url	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022015000200022
work_keys_str_mv	AT almansourmansour morphometricalterationsinducedbythetoxicityofvariablesizesofsilvernanoparticles AT jarrarqais morphometricalterationsinducedbythetoxicityofvariablesizesofsilvernanoparticles AT battahabdelkader morphometricalterationsinducedbythetoxicityofvariablesizesofsilvernanoparticles AT jarrarbashir morphometricalterationsinducedbythetoxicityofvariablesizesofsilvernanoparticles
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Morphometric Alterations Induced by the Toxicity of Variable Sizes of Silver Nanoparticles

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